Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor

July 11th, 2016 by Alem W Kahsai

Nature Chemical Biology 12, 709 (2016). doi:10.1038/nchembio.2126

Authors: Alem W Kahsai, James W Wisler, Jungmin Lee, Seungkirl Ahn, Thomas J Cahill III, S Moses Dennison, Dean P Staus, Alex R B Thomsen, Kara M Anasti, Biswaranjan Pani, Laura M Wingler, Hemant Desai, Kristin M Bompiani, Ryan T Strachan, Xiaoxia Qin, S Munir Alam, Bruce A Sullenger & Robert J Lefkowitz

  • Posted in Nat Chem Biol, Publications
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Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage

July 11th, 2016 by Aiming Ren

Nature Chemical Biology 12, 702 (2016). doi:10.1038/nchembio.2125

Authors: Aiming Ren, Nikola Vušurović, Jennifer Gebetsberger, Pu Gao, Michael Juen, Christoph Kreutz, Ronald Micura & Dinshaw J Patel

  • Posted in Nat Chem Biol, Publications
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Tbx16 regulates hox gene activation in mesodermal progenitor cells

July 4th, 2016 by Alexander Y Payumo

Nature Chemical Biology 12, 694 (2016). doi:10.1038/nchembio.2124

Authors: Alexander Y Payumo, Lindsey E McQuade, Whitney J Walker, Sayumi Yamazoe & James K Chen

ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity

July 4th, 2016 by Baoen Chen

Nature Chemical Biology 12, 686 (2016). doi:10.1038/nchembio.2119

Authors: Baoen Chen, Baohui Zheng, Michael DeRan, Gopala K Jarugumilli, Jianjun Fu, Yang S Brooks & Xu Wu

Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition

July 4th, 2016 by Anja F Hohmann

Nature Chemical Biology 12, 672 (2016). doi:10.1038/nchembio.2115

Authors: Anja F Hohmann, Laetitia J Martin, Jessica L Minder, Jae-Seok Roe, Junwei Shi, Steffen Steurer, Gerd Bader, Darryl McConnell, Mark Pearson, Thomas Gerstberger, Teresa Gottschamel, Diane Thompson, Yutaka Suzuki, Manfred Koegl & Christopher R Vakoc

  • Posted in Nat Chem Biol, Publications
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A reactivity-based probe of the intracellular labile ferrous iron pool

July 4th, 2016 by Benjamin Spangler

Nature Chemical Biology 12, 680 (2016). doi:10.1038/nchembio.2116

Authors: Benjamin Spangler, Charles W Morgan, Shaun D Fontaine, Mark N Vander Wal, Christopher J Chang, James A Wells & Adam R Renslo

  • Posted in Nat Chem Biol, Publications
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Identification of Cyanobacteriochromes Detecting Far-Red Light

July 2nd, 2016 by Nathan C. Rockwell, Shelley S. Martin and J. Clark Lagarias

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Biochemistry
DOI: 10.1021/acs.biochem.6b00299

Benchmarking of TALE- and CRISPR/dCas9-Based Transcriptional Regulators in Mammalian Cells for the Construction of Synthetic Genetic Circuits

June 28th, 2016 by Tina Lebar and Roman Jerala

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ACS Synthetic Biology
DOI: 10.1021/acssynbio.5b00259
  • Posted in ACS Synthetic Biology, Publications
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Loss of protein association causes cardiolipin degradation in Barth syndrome

June 27th, 2016 by Yang Xu

Nature Chemical Biology 12, 641 (2016). doi:10.1038/nchembio.2113

Authors: Yang Xu, Colin K L Phoon, Bob Berno, Kenneth D'Souza, Esthelle Hoedt, Guoan Zhang, Thomas A Neubert, Richard M Epand, Mindong Ren & Michael Schlame

  • Posted in Nat Chem Biol, Publications
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Precursors of tRNAs are stabilized by methylguanosine cap structures

June 27th, 2016 by Takayuki Ohira

Nature Chemical Biology 12, 648 (2016). doi:10.1038/nchembio.2117

Authors: Takayuki Ohira & Tsutomu Suzuki