Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation
November 13th, 2017 by Brittney A Beyer
Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation
Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation, Published online: 13 November 2017; doi:10.1038/nchembio.2517
NatureArticleSnippet(type=short-summary, markup=Mass-spectrometry-based metabolomics analysis of oligodendrocyte differentiation led to the identification of an endogenous metabolite, taurine, that enhanced the process of drug-induced OPC differentiation.
Purinyl-cobamide is a native prosthetic group of reductive dehalogenases
November 6th, 2017 by Jun Yan
Purinyl-cobamide is a native prosthetic group of reductive dehalogenases
Purinyl-cobamide is a native prosthetic group of reductive dehalogenases, Published online: 06 November 2017; doi:10.1038/nchembio.2512
NatureArticleSnippet(type=short-summary, markup=In organohalide-respiring bacteria, reductive dehalogenases cleave carbon–halogen bonds using cobamide prosthetic groups.
Ultrasensitive optical imaging with lanthanide lumiphores
November 6th, 2017 by Ukrae Cho
Ultrasensitive optical imaging with lanthanide lumiphores
Ultrasensitive optical imaging with lanthanide lumiphores, Published online: 06 November 2017; doi:10.1038/nchembio.2513
NatureArticleSnippet(type=short-summary, markup=Ultrasensitive imaging of lanthanide chelates is achieved by integrating transreflected illumination, luminescence resonance energy transfer, and time-resolved microscopy.
Biosynthesis of an Opine Metallophore by Pseudomonas aeruginosa
November 3rd, 2017 by Jeffrey S. McFarlane and Audrey L. Lamb
Large Scale Mutational and Kinetic Analysis of a Self-Hydrolyzing Deoxyribozyme
November 3rd, 2017 by V. Dhamodharan, Shungo Kobori and Yohei Yokobayashi
Synthetic beta cells for fusion-mediated dynamic insulin secretion
October 30th, 2017 by Zhaowei Chen
Synthetic beta cells for fusion-mediated dynamic insulin secretion
Synthetic beta cells for fusion-mediated dynamic insulin secretion, Published online: 30 October 2017; doi:10.1038/nchembio.2511
NatureArticleSnippet(type=short-summary, markup=Synthetic beta cells were fabricated through 'vesicles-in-vesicle' liposomal superstructures equipped with glucose-sensing and membrane-fusion machinery, thus enabling sensing of graded glucose levels and secretion of insulin via fusion processes.
PatB1 is an <i>O</i>-acetyltransferase that decorates secondary cell wall polysaccharides
October 30th, 2017 by David Sychantha
PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides
PatB1 is an <i>O</i>-acetyltransferase that decorates secondary cell wall polysaccharides, Published online: 30 October 2017; doi:10.1038/nchembio.2509
NatureArticleSnippet(type=short-summary, markup=A chemically synthesized analog of
Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer
October 30th, 2017 by Yi Qu
Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer
Small molecule promotes β-catenin citrullination and inhibits Wnt signaling in cancer, Published online: 30 October 2017; doi:10.1038/nchembio.2510
NatureArticleSnippet(type=short-summary, markup=The small molecule nitazoxanide (NTZ) was identified as a Wnt inhibitor by promoting protein citrullination of β-catenin through increased cytosolic calcium and PAD2 protein stabilization. β-catenin citrullination results in proteasomal degradation.
The Conformational Change in Elongation Factor Tu Involves Separation of Its Domains
October 27th, 2017 by Jonathan Lai, Zhaleh Ghaemi and Zaida Luthey-Schulten
Correction to Probing the Binding Mechanism of Mnk Inhibitors by Docking and Molecular Dynamics Simulations
October 27th, 2017 by Srinivasaraghavan Kannan, Anders Poulsen, Hai Yan Yang, Melvyn Ho, Shi Hua Ang, Tan Sum Wai Eldwin, Duraiswamy Athisayamani Jeyaraj, Lohitha Rao Chennamaneni, Boping Liu, Jeffrey Hill, Chandra S. Verma and Kassoum Nacro