Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants

June 26th, 2017 by Craig A Schenck

Nature Chemical Biology 13, 1029 (2017). doi:10.1038/nchembio.2414

Authors: Craig A Schenck, Cynthia K Holland, Matthew R Schneider, Yusen Men, Soon Goo Lee, Joseph M Jez & Hiroshi A Maeda

  • Posted in Nat Chem Biol, Publications
  • Comments Off on Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants

2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 superagonist

June 26th, 2017 by Ralf Fliegert

Nature Chemical Biology 13, 1036 (2017). doi:10.1038/nchembio.2415

Authors: Ralf Fliegert, Andreas Bauche, Adriana-Michelle Wolf Pérez, Joanna M Watt, Monika D Rozewitz, Riekje Winzer, Mareike Janus, Feng Gu, Annette Rosche, Angelika Harneit, Marianne Flato, Christelle Moreau, Tanja Kirchberger, Valerie Wolters, Barry V L Potter & Andreas H Guse

  • Posted in Nat Chem Biol, Publications
  • Comments Off on 2′-Deoxyadenosine 5′-diphosphoribose is an endogenous TRPM2 superagonist

A new strategy for aromatic ring alkylation in cylindrocyclophane biosynthesis

June 26th, 2017 by Hitomi Nakamura

Nature Chemical Biology 13, 916 (2017). doi:10.1038/nchembio.2421

Authors: Hitomi Nakamura, Erica E Schultz & Emily P Balskus

  • Posted in Nat Chem Biol, Publications
  • Comments Off on A new strategy for aromatic ring alkylation in cylindrocyclophane biosynthesis

De Novo Biosynthesis of Glutarate via α-Keto Acid Carbon Chain Extension and Decarboxylation Pathway in Escherichia coli

June 23rd, 2017 by Jian Wang, Yifei Wu, Xinxiao Sun, Qipeng Yuan and Yajun Yan

TOC Graphic

ACS Synthetic Biology
DOI: 10.1021/acssynbio.7b00136
  • Posted in ACS Synthetic Biology, Publications
  • Comments Off on De Novo Biosynthesis of Glutarate via α-Keto Acid Carbon Chain Extension and Decarboxylation Pathway in Escherichia coli

Targeting the N terminus for site-selective protein modification

June 20th, 2017 by Christian B Rosen

Nature Chemical Biology 13, 697 (2017). doi:10.1038/nchembio.2416

Authors: Christian B Rosen & Matthew B Francis

Metal homeostasis: Pumping iron

June 20th, 2017 by Grant Miura

Nature Chemical Biology 13, 693 (2017). doi:10.1038/nchembio.2423

Author: Grant Miura

Antimicrobials: Targeting fungal chromatin

June 20th, 2017 by Stéphane Larochelle

Nature Chemical Biology 13, 693 (2017). doi:10.1038/nchembio.2424

Author: Stéphane Larochelle

Circadian regulation: Switching periods

June 20th, 2017 by Grant Miura

Nature Chemical Biology 13, 693 (2017). doi:10.1038/nchembio.2426

Author: Grant Miura

Synthetic biology: Playing favorites

June 20th, 2017 by Ross Cloney

Nature Chemical Biology 13, 693 (2017). doi:10.1038/nchembio.2425

Author: Ross Cloney

Peptidoglycan: Another brick in the wall

June 20th, 2017 by Anthony J Clarke

Nature Chemical Biology 13, 695 (2017). doi:10.1038/nchembio.2419

Author: Anthony J Clarke

Lipid II embodies the bricks used to build the essential bacterial cell wall component peptidoglycan. A facile new procedure for preparation of species-specific Lipid II in high yields can now be used to unlock the door to antibiotic discovery.