Illuminating developmental biology through photochemistry

May 17th, 2017 by Lukasz Kowalik

Nature Chemical Biology 13, 587 (2017). doi:10.1038/nchembio.2369

Authors: Lukasz Kowalik & James K Chen

Small-molecule phenotypic screening with stem cells

May 17th, 2017 by Andrei Ursu

Nature Chemical Biology 13, 560 (2017). doi:10.1038/nchembio.2383

Authors: Andrei Ursu, Hans R Schöler & Herbert Waldmann

To fully leverage the potential of human-induced pluripotent stem cells (hiPSCs), improved and standardized reprogramming methods and large-scale collections of hiPSC lines are needed, and the stem cell community must embrace chemical biology methodology for target identification and validation.

The perception of strigolactones in vascular plants

May 17th, 2017 by Shelley Lumba

Nature Chemical Biology 13, 599 (2017). doi:10.1038/nchembio.2340

Authors: Shelley Lumba, Duncan Holbrook-Smith & Peter McCourt

Infectious disease: A lethal sugar fix

May 17th, 2017 by Alison Farrell

Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2400

Author: Alison Farrell

Shaping embryonic development

May 17th, 2017 by Nature Chemical Biology - Issue - science feeds

Nature Chemical Biology 13, 559 (2017). doi:10.1038/nchembio.2403

The growing intersection between chemical tools and principles and developmental biology is providing new insights into the molecular-level details of developmental processes.

Unraveling cell-to-cell signaling networks with chemical biology

May 17th, 2017 by Zev J Gartner

Nature Chemical Biology 13, 564 (2017). doi:10.1038/nchembio.2391

Authors: Zev J Gartner, Jennifer A Prescher & Luke D Lavis

Cell-to-cell signaling networks, although poorly understood, guide tissue development, regulate tissue function and may become dysregulated in disease. Chemical biologists can develop the next generation of tools to untangle these complex and dynamic networks of interacting cells.

Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain

May 17th, 2017 by Sathish Srinivasan

Nature Chemical Biology 13, 691 (2017). doi:10.1038/nchembio0617-691c

Author: Sathish Srinivasan, Jerome C Nwachukwu, Nelson E Bruno, Venkatasubramanian Dharmarajan, Devrishi Goswami, Irida Kastrati, Scott Novick, Jason Nowak, Valerie Cavett, Hai-Bing Zhou, Nittaya Boonmuen, Yuechao Zhao, Jian Min, Jonna Frasor, Benita S Katzenellenbogen, Patrick R Griffin, John A Katzenellenbogen & Kendall W Nettles

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Enzymology: Radical ring resizing

May 17th, 2017 by Caitlin Deane

Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2399

Author: Caitlin Deane

Synthetic biology: Return to sender

May 17th, 2017 by Grant Miura

Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2398

Author: Grant Miura

Plant development: Get lit on steroids

May 17th, 2017 by Mirella Bucci

Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2401

Author: Mirella Bucci