Illuminating developmental biology through photochemistry
May 17th, 2017 by Lukasz Kowalik
Nature Chemical Biology 13, 587 (2017). doi:10.1038/nchembio.2369
Authors: Lukasz Kowalik & James K Chen
Small-molecule phenotypic screening with stem cells
May 17th, 2017 by Andrei Ursu
Nature Chemical Biology 13, 560 (2017). doi:10.1038/nchembio.2383
Authors: Andrei Ursu, Hans R Schöler & Herbert Waldmann
To fully leverage the potential of human-induced pluripotent stem cells (hiPSCs), improved and standardized reprogramming methods and large-scale collections of hiPSC lines are needed, and the stem cell community must embrace chemical biology methodology for target identification and validation.
The perception of strigolactones in vascular plants
May 17th, 2017 by Shelley Lumba
Nature Chemical Biology 13, 599 (2017). doi:10.1038/nchembio.2340
Authors: Shelley Lumba, Duncan Holbrook-Smith & Peter McCourt
Infectious disease: A lethal sugar fix
May 17th, 2017 by Alison Farrell
Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2400
Author: Alison Farrell
Shaping embryonic development
May 17th, 2017 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology 13, 559 (2017). doi:10.1038/nchembio.2403
The growing intersection between chemical tools and principles and developmental biology is providing new insights into the molecular-level details of developmental processes.
Unraveling cell-to-cell signaling networks with chemical biology
May 17th, 2017 by Zev J Gartner
Nature Chemical Biology 13, 564 (2017). doi:10.1038/nchembio.2391
Authors: Zev J Gartner, Jennifer A Prescher & Luke D Lavis
Cell-to-cell signaling networks, although poorly understood, guide tissue development, regulate tissue function and may become dysregulated in disease. Chemical biologists can develop the next generation of tools to untangle these complex and dynamic networks of interacting cells.
Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain
May 17th, 2017 by Sathish Srinivasan
Nature Chemical Biology 13, 691 (2017). doi:10.1038/nchembio0617-691c
Author: Sathish Srinivasan, Jerome C Nwachukwu, Nelson E Bruno, Venkatasubramanian Dharmarajan, Devrishi Goswami, Irida Kastrati, Scott Novick, Jason Nowak, Valerie Cavett, Hai-Bing Zhou, Nittaya Boonmuen, Yuechao Zhao, Jian Min, Jonna Frasor, Benita S Katzenellenbogen, Patrick R Griffin, John A Katzenellenbogen & Kendall W Nettles
Enzymology: Radical ring resizing
May 17th, 2017 by Caitlin Deane
Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2399
Author: Caitlin Deane
Synthetic biology: Return to sender
May 17th, 2017 by Grant Miura
Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2398
Author: Grant Miura
Plant development: Get lit on steroids
May 17th, 2017 by Mirella Bucci
Nature Chemical Biology 13, 569 (2017). doi:10.1038/nchembio.2401
Author: Mirella Bucci