Protein Plasticity and Peptide Editing in the MHC I Antigen Processing Pathway

February 22nd, 2018 by Tim Elliott and Andy van Hateren

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Biochemistry
DOI: 10.1021/acs.biochem.7b01307

Orthogonal Information Encoding in Living Cells with High Error-Tolerance, Safety, and Fidelity

February 21st, 2018 by Lifu Song and An-Ping Zeng

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ACS Synthetic Biology
DOI: 10.1021/acssynbio.7b00382

More Than a Light Switch: Engineering Unconventional Fluorescent Configurations for Biological Sensing

February 20th, 2018 by William J. Peveler and W. Russ Algar

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b01022
  • Posted in ACS Chemical Biology, Publications
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Oxidative demethylation of algal carbohydrates by cytochrome P450 monooxygenases

February 19th, 2018 by Lukas Reisky

Oxidative demethylation of algal carbohydrates by cytochrome P450 monooxygenases

Oxidative demethylation of algal carbohydrates by cytochrome P450 monooxygenases, Published online: 19 February 2018; doi:10.1038/s41589-018-0005-8

The discovery of cytochrome P450 monooxygenases that catalyze oxidative demethylation of 6-O-methyl-d-galactose reveals a new activity of cytochrome P450 enzymes and their role in polysaccharide biomass degradation in marine bacteria.
  • Posted in Nat Chem Biol, Publications
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Viruses: Capsids under pressure

February 14th, 2018 by Mirella Bucci

Viruses: Capsids under pressure

Viruses: Capsids under pressure, Published online: 14 February 2018; doi:10.1038/nchembio.2578

Viruses: Capsids under pressure

How many human proteoforms are there?

February 14th, 2018 by Ruedi Aebersold

How many human proteoforms are there?

How many human proteoforms are there?, Published online: 14 February 2018; doi:10.1038/nchembio.2576

How many human proteoforms are there?

Insights into the biogenesis, function, and regulation of ADP-ribosylation

February 14th, 2018 by Michael S Cohen

Insights into the biogenesis, function, and regulation of ADP-ribosylation

Insights into the biogenesis, function, and regulation of ADP-ribosylation, Published online: 14 February 2018; doi:10.1038/nchembio.2568

Insights into the biogenesis, function, and regulation of ADP-ribosylation
  • Posted in Nat Chem Biol, Publications
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RNA structure: A LASER-focused view into cells

February 14th, 2018 by Philip C Bevilacqua

RNA structure: A LASER-focused view into cells

RNA structure: A LASER-focused view into cells, Published online: 14 February 2018; doi:10.1038/nchembio.2570

RNA structure is irrevocably linked to function. A new method, termed 'LASER', utilizes a light-activated chemical probe to query RNA tertiary structure and illuminate RNA–protein interactions in the living cell.

The ABCs of PTMs

February 14th, 2018 by Karl W Barber

The ABCs of PTMs

The ABCs of PTMs, Published online: 14 February 2018; doi:10.1038/nchembio.2572

Post-translational modifications (PTMs) are ubiquitous in all forms of life and often modulate critical protein functions. Recent chemical and biological advances have finally enabled scientists to precisely modify proteins at physiologically relevant positions, ushering in a new era of protein studies.

Ubiquitination: Trashing the CIA

February 14th, 2018 by Grant Miura

Ubiquitination: Trashing the CIA

Ubiquitination: Trashing the CIA, Published online: 14 February 2018; doi:10.1038/nchembio.2580

Ubiquitination: Trashing the CIA