A New Nucleoside Antibiotic Chokes Bacterial RNA Polymerase

September 8th, 2017 by Eric P. Trautman and Jason M. Crawford

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Biochemistry
DOI: 10.1021/acs.biochem.7b00680

Ionic Strength Sensing in Living Cells

September 6th, 2017 by Boqun Liu, Bert Poolman and Arnold J. Boersma

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00348

Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8

August 30th, 2017 by Nicholas J. Porter and David W. Christianson

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00330

Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel

August 28th, 2017 by Mikhail Metelev

Nature Chemical Biology 13, 1129 (2017). doi:10.1038/nchembio.2462

Authors: Mikhail Metelev, Ilya A Osterman, Dmitry Ghilarov, Nelli F Khabibullina, Alexander Yakimov, Konstantin Shabalin, Irina Utkina, Dmitry Y Travin, Ekaterina S Komarova, Marina Serebryakova, Tatyana Artamonova, Mikhail Khodorkovskii, Andrey L Konevega, Petr V Sergiev, Konstantin Severinov & Yury S Polikanov

  • Posted in Nat Chem Biol, Publications
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Oxidative cleavage of polysaccharides by monocopper enzymes depends on H2O2

August 28th, 2017 by Bastien Bissaro

Nature Chemical Biology 13, 1123 (2017). doi:10.1038/nchembio.2470

Authors: Bastien Bissaro, Åsmund K Røhr, Gerdt Müller, Piotr Chylenski, Morten Skaugen, Zarah Forsberg, Svein J Horn, Gustav Vaaje-Kolstad & Vincent G H Eijsink

  • Posted in Nat Chem Biol, Publications
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Staphylococcus aureus CidC Is a Pyruvate:Menaquinone Oxidoreductase

August 25th, 2017 by Xinyan Zhang, Kenneth W. Bayles and Sorin Luca

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Biochemistry
DOI: 10.1021/acs.biochem.7b00570

Regulatory Mechanism of Mycotoxin Tenuazonic Acid Production in Pyricularia oryzae

August 24th, 2017 by Choong-Soo Yun, Takayuki Motoyama and Hiroyuki Osada

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ACS Chemical Biology
DOI: 10.1021/acschembio.7b00353

Metals induce transient folding and activation of the twister ribozyme

August 21st, 2017 by Subrata Panja

Nature Chemical Biology 13, 1109 (2017). doi:10.1038/nchembio.2459

Authors: Subrata Panja, Boyang Hua, Diego Zegarra, Taekjip Ha & Sarah A Woodson

  • Posted in Nat Chem Biol, Publications
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Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529

August 21st, 2017 by Marie Pancera

Nature Chemical Biology 13, 1115 (2017). doi:10.1038/nchembio.2460

Authors: Marie Pancera, Yen-Ting Lai, Tatsiana Bylund, Aliaksandr Druz, Sandeep Narpala, Sijy O'Dell, Arne Schön, Robert T Bailer, Gwo-Yu Chuang, Hui Geng, Mark K Louder, Reda Rawi, Djade I Soumana, Andrés Finzi, Alon Herschhorn, Navid Madani, Joseph Sodroski, Ernesto Freire, David R Langley, John R Mascola, Adrian B McDermott & Peter D Kwong

  • Posted in Nat Chem Biol, Publications
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Controlling Bdellovibrio bacteriovorus Gene Expression and Predation Using Synthetic Riboswitches

August 18th, 2017 by Mohammed Dwidar and Yohei Yokobayashi

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ACS Synthetic Biology
DOI: 10.1021/acssynbio.7b00171