Corrigendum: Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists

August 18th, 2015 by Xiao Hu

Nature Chemical Biology 11, 741 (2015). doi:10.1038/nchembio0915-741b

Author: Xiao Hu, Yahong Wang, Ling-Yang Hao, Xikui Liu, Chuck A Lesch, Brian M Sanchez, Jay M Wendling, Rodney W Morgan, Tom D Aicher, Laura L Carter, Peter L Toogood & Gary D Glick

  • Posted in Nat Chem Biol, Publications
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Reinvigorating natural product combinatorial biosynthesis with synthetic biology

August 18th, 2015 by Eunji Kim

Nature Chemical Biology 11, 649 (2015). doi:10.1038/nchembio.1893

Authors: Eunji Kim, Bradley S Moore & Yeo Joon Yoon

  • Posted in Nat Chem Biol, Publications
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Corrigendum: Local and macroscopic electrostatic interactions in single α-helices

August 18th, 2015 by Emily G Baker

Nature Chemical Biology 11, 741 (2015). doi:10.1038/nchembio0915-741e

Author: Emily G Baker, Gail J Bartlett, Matthew P Crump, Richard B Sessions, Noah Linden, Charl F J Faul & Derek N Woolfson

  • Posted in Nat Chem Biol, Publications
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Plant microbiota: Root recruiting

August 18th, 2015 by Mirella Bucci

Nature Chemical Biology 11, 632 (2015). doi:10.1038/nchembio.1900

Author: Mirella Bucci

Erratum: Structural basis of enzymatic benzene ring reduction

August 18th, 2015 by Tobias Weinert

Nature Chemical Biology 11, 741 (2015). doi:10.1038/nchembio0915-741d

Author: Tobias Weinert, Simona G Huwiler, Johannes W Kung, Sina Weidenweber, Petra Hellwig, Hans-Joachim Stärk, Till Biskup, Stefan Weber, Julien J H Cotelesage, Graham N George, Ulrich Ermler & Matthias Boll

Microbiome: Adapting to mucus

August 18th, 2015 by Stéphane Larochelle

Nature Chemical Biology 11, 633 (2015). doi:10.1038/nchembio.1904

Author: Stéphane Larochelle

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

August 18th, 2015 by James Palacino

Nature Chemical Biology 11, 741 (2015). doi:10.1038/nchembio0915-741a

Author: James Palacino, Susanne E Swalley, Cheng Song, Atwood K Cheung, Lei Shu, Xiaolu Zhang, Mailin Van Hoosear, Youngah Shin, Donovan N Chin, Caroline Gubser Keller, Martin Beibel, Nicole A Renaud, Thomas M Smith, Michael Salcius, Xiaoying Shi, Marc Hild, Rebecca Servais, Monish Jain, Lin Deng, Caroline Bullock, Michael McLellan, Sven Schuierer, Leo Murphy, Marcel J J Blommers, Cecile Blaustein, Frada Berenshteyn, Arnaud Lacoste, Jason R Thomas, Guglielmo Roma, Gregory A Michaud, Brian S Tseng, Jeffery A Porter, Vic E Myer, John A Tallarico, Lawrence G Hamann, Daniel Curtis, Mark C Fishman, William F Dietrich, Natalie A Dales & Rajeev Sivasankaran

  • Posted in Nat Chem Biol, Publications
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Cell cycle regulation: Redox shielding

August 18th, 2015 by Grant Miura

Nature Chemical Biology 11, 632 (2015). doi:10.1038/nchembio.1901

Author: Grant Miura

Erratum: Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs

August 18th, 2015 by Lingyin Li

Nature Chemical Biology 11, 741 (2015). doi:10.1038/nchembio0915-741c

Author: Lingyin Li, Qian Yin, Pia Kuss, Zoltan Maliga, José L Millán, Hao Wu & Timothy J Mitchison

  • Posted in Nat Chem Biol, Publications
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Carbohydrates: A phenol sandwich fights diabetes

August 18th, 2015 by Anna Bernardi

Nature Chemical Biology 11, 635 (2015). doi:10.1038/nchembio.1888

Authors: Anna Bernardi & Sara Sattin

The complex flavonoid montbretin A (MbA) is a powerful inhibitor of human pancreatic amylase (HPA) and a potential tool in the treatment of type 2 diabetes. The X-ray structure of the MbA–HPA complex now shows that a hydrophobic collapse of two phenol fragments in the structure of MbA is key to its activity.