Real-time intravital imaging of pH variation associated with osteoclast activity

June 6th, 2016 by Hiroki Maeda

Nature Chemical Biology 12, 579 (2016). doi:10.1038/nchembio.2096

Authors: Hiroki Maeda, Toshiyuki Kowada, Junichi Kikuta, Masayuki Furuya, Mai Shirazaki, Shin Mizukami, Masaru Ishii & Kazuya Kikuchi

  • Posted in Nat Chem Biol, Publications
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Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes

May 30th, 2016 by Simon Wisnovsky

Nature Chemical Biology 12, 567 (2016). doi:10.1038/nchembio.2102

Authors: Simon Wisnovsky, Sae Rin Jean & Shana O Kelley

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Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds

May 30th, 2016 by Giancarlo Bruni

Nature Chemical Biology 12, 559 (2016). doi:10.1038/nchembio.2097

Authors: Giancarlo Bruni, Andrew J Rennekamp, Andrea Velenich, Matthew McCarroll, Leo Gendelev, Ethan Fertsch, Jack Taylor, Parth Lakhani, Dennis Lensen, Tama Evron, Paul J Lorello, Xi-Ping Huang, Sabine Kolczewski, Galen Carey, Barbara J Caldarone, Eric Prinssen, Bryan L Roth, Michael J Keiser, Randall T Peterson & David Kokel

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σ1 receptor ligands control a switch between passive and active threat responses

May 30th, 2016 by Andrew J Rennekamp

Nature Chemical Biology 12, 552 (2016). doi:10.1038/nchembio.2089

Authors: Andrew J Rennekamp, Xi-Ping Huang, You Wang, Samir Patel, Paul J Lorello, Lindsay Cade, Andrew P W Gonzales, Jing-Ruey Joanna Yeh, Barbara J Caldarone, Bryan L Roth, David Kokel & Randall T Peterson

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NSUN3 methylase initiates 5-formylcytidine biogenesis in human mitochondrial tRNAMet

May 23rd, 2016 by Saori Nakano

Nature Chemical Biology 12, 546 (2016). doi:10.1038/nchembio.2099

Authors: Saori Nakano, Takeo Suzuki, Layla Kawarada, Hiroyoshi Iwata, Kana Asano & Tsutomu Suzuki

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An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

May 23rd, 2016 by Maia Vinogradova

Nature Chemical Biology 12, 531 (2016). doi:10.1038/nchembio.2085

Authors: Maia Vinogradova, Victor S Gehling, Amy Gustafson, Shilpi Arora, Charles A Tindell, Catherine Wilson, Kaylyn E Williamson, Gulfem D Guler, Pranoti Gangurde, Wanda Manieri, Jennifer Busby, E Megan Flynn, Fei Lan, Hyo-jin Kim, Shobu Odate, Andrea G Cochran, Yichin Liu, Matthew Wongchenko, Yibin Yang, Tommy K Cheung, Tobias M Maile, Ted Lau, Michael Costa, Ganapati V Hegde, Erica Jackson, Robert Pitti, David Arnott, Christopher Bailey, Steve Bellon, Richard T Cummings, Brian K Albrecht, Jean-Christophe Harmange, James R Kiefer, Patrick Trojer & Marie Classon

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Structural analysis of human KDM5B guides histone demethylase inhibitor development

May 23rd, 2016 by Catrine Johansson

Nature Chemical Biology 12, 539 (2016). doi:10.1038/nchembio.2087

Authors: Catrine Johansson, Srikannathasan Velupillai, Anthony Tumber, Aleksandra Szykowska, Edward S Hookway, Radoslaw P Nowak, Claire Strain-Damerell, Carina Gileadi, Martin Philpott, Nicola Burgess-Brown, Na Wu, Jola Kopec, Andrea Nuzzi, Holger Steuber, Ursula Egner, Volker Badock, Shonagh Munro, Nicholas B LaThangue, Sue Westaway, Jack Brown, Nick Athanasou, Rab Prinjha, Paul E Brennan & Udo Oppermann

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Host–microbe interactions: Inflammation sop-up

May 18th, 2016 by Mirella Bucci

Nature Chemical Biology 12, 387 (2016). doi:10.1038/nchembio.2095

Author: Mirella Bucci

Genomics: A Tribe for RNA

May 18th, 2016 by Grant Miura

Nature Chemical Biology 12, 387 (2016). doi:10.1038/nchembio.2092

Author: Grant Miura

Protein evolution: Polymerase’s new language

May 18th, 2016 by Caitlin Deane

Nature Chemical Biology 12, 387 (2016). doi:10.1038/nchembio.2094

Author: Caitlin Deane