Decoding Polo-like kinase 1 signaling along the kinetochore–centromere axis

April 4th, 2016 by Robert F Lera

Nature Chemical Biology 12, 411 (2016). doi:10.1038/nchembio.2060

Authors: Robert F Lera, Gregory K Potts, Aussie Suzuki, James M Johnson, Edward D Salmon, Joshua J Coon & Mark E Burkard

  • Posted in Nat Chem Biol, Publications
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Raft-based interactions of gangliosides with a GPI-anchored receptor

April 4th, 2016 by Naoko Komura

Nature Chemical Biology 12, 402 (2016). doi:10.1038/nchembio.2059

Authors: Naoko Komura, Kenichi G N Suzuki, Hiromune Ando, Miku Konishi, Machi Koikeda, Akihiro Imamura, Rahul Chadda, Takahiro K Fujiwara, Hisae Tsuboi, Ren Sheng, Wonhwa Cho, Koichi Furukawa, Keiko Furukawa, Yoshio Yamauchi, Hideharu Ishida, Akihiro Kusumi & Makoto Kiso

Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling

March 28th, 2016 by Geoffrey A Smith

Nature Chemical Biology 12, 373 (2016). doi:10.1038/nchembio.2056

Authors: Geoffrey A Smith, Kenji Uchida, Arthur Weiss & Jack Taunton

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AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs

March 28th, 2016 by William H Parsons

Nature Chemical Biology 12, 367 (2016). doi:10.1038/nchembio.2051

Authors: William H Parsons, Matthew J Kolar, Siddhesh S Kamat, Armand B Cognetta III, Jonathan J Hulce, Enrique Saez, Barbara B Kahn, Alan Saghatelian & Benjamin F Cravatt

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Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification

March 28th, 2016 by Richard M Deans

Nature Chemical Biology 12, 361 (2016). doi:10.1038/nchembio.2050

Authors: Richard M Deans, David W Morgens, Ayşe Ökesli, Sirika Pillay, Max A Horlbeck, Martin Kampmann, Luke A Gilbert, Amy Li, Roberto Mateo, Mark Smith, Jeffrey S Glenn, Jan E Carette, Chaitan Khosla & Michael C Bassik

  • Posted in Nat Chem Biol, Publications
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Steric trapping reveals a cooperativity network in the intramembrane protease GlpG

March 21st, 2016 by Ruiqiong Guo

Nature Chemical Biology 12, 353 (2016). doi:10.1038/nchembio.2048

Authors: Ruiqiong Guo, Kristen Gaffney, Zhongyu Yang, Miyeon Kim, Suttipun Sungsuwan, Xuefei Huang, Wayne L Hubbell & Heedeok Hong

  • Posted in Nat Chem Biol, Publications
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Exploiting nongenetic cell-to-cell variation for enhanced biosynthesis

March 21st, 2016 by Yi Xiao

Nature Chemical Biology 12, 339 (2016). doi:10.1038/nchembio.2046

Authors: Yi Xiao, Christopher H Bowen, Di Liu & Fuzhong Zhang

  • Posted in Nat Chem Biol, Publications
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Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage

March 21st, 2016 by Ling Liu

Nature Chemical Biology 12, 345 (2016). doi:10.1038/nchembio.2047

Authors: Ling Liu, Supriya Shah, Jing Fan, Junyoung O Park, Kathryn E Wellen & Joshua D Rabinowitz

  • Posted in Nat Chem Biol, Publications
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Corrigendum: Frequency and amplitude control of cortical oscillations by phosphoinositide waves

March 18th, 2016 by Ding Xiong

Nature Chemical Biology 12, 304 (2016). doi:10.1038/nchembio0416-304b

Author: Ding Xiong, Shengping Xiao, Su Guo, Qingsong Lin, Fubito Nakatsu & Min Wu

  • Posted in Nat Chem Biol, Publications
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Toxin-antitoxin systems in bacterial growth arrest and persistence

March 18th, 2016 by Rebecca Page

Nature Chemical Biology 12, 208 (2016). doi:10.1038/nchembio.2044

Authors: Rebecca Page & Wolfgang Peti