The pharmacological regulation of cellular mitophagy

January 19th, 2017 by Nikolaos D Georgakopoulos

Nature Chemical Biology 13, 136 (2017). doi:10.1038/nchembio.2287

Authors: Nikolaos D Georgakopoulos, Geoff Wells & Michelangelo Campanella

Synthetic biology: Sensing with modular receptors

January 19th, 2017 by Matthew Brenner

Nature Chemical Biology 13, 131 (2017). doi:10.1038/nchembio.2290

Authors: Matthew Brenner, Jang Hwan Cho & Wilson W Wong

Sensing and responding to diverse extracellular signals is a crucial aspect of cellular decision-making that is currently lacking in the synthetic biology toolkit. The development of modular receptor platforms allows for the rewiring of cellular input–output relationships.

Susan Lindquist (1949–2016)

January 19th, 2017 by Tricia R Serio

Nature Chemical Biology 13, 127 (2017). doi:10.1038/nchembio.2305

Author: Tricia R Serio

Susan Lindquist passed away on 27 October 2016, far too early for those who marveled at her brilliance through her many contributions to science, for all who knew her directly, and especially for her former trainees.

RNA modification: Reading Sex-lethal

January 19th, 2017 by Grant Miura

Nature Chemical Biology 13, 129 (2017). doi:10.1038/nchembio.2291

Author: Grant Miura

Nitrogenase: A fuel-producing microbe

January 19th, 2017 by Holger Dobbek

Nature Chemical Biology 13, 134 (2017). doi:10.1038/nchembio.2288

Author: Holger Dobbek

Nitrogenase has the canonical ability to reduce N2 to NH3, but under certain conditions, either in vitro or in vivo, it has the additional capability to convert CO2 to CO and CO to light hydrocarbons.

Biosynthesis: Terrifically tailored peptides

January 19th, 2017 by Caitlin Deane

Nature Chemical Biology 13, 129 (2017). doi:10.1038/nchembio.2292

Author: Caitlin Deane

Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress

January 16th, 2017 by Nathan P Westcott

Nature Chemical Biology 13, 302 (2017). doi:10.1038/nchembio.2280

Authors: Nathan P Westcott, Joseph P Fernandez, Henrik Molina & Howard C Hang

  • Posted in Nat Chem Biol, Publications
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Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis

January 16th, 2017 by Matthew J Rodrigues

Nature Chemical Biology 13, 290 (2017). doi:10.1038/nchembio.2273

Authors: Matthew J Rodrigues, Volker Windeisen, Yang Zhang, Gabriela Guédez, Stefan Weber, Marco Strohmeier, Jeremiah W Hanes, Antoine Royant, Gwyndaf Evans, Irmgard Sinning, Steven E Ealick, Tadhg P Begley & Ivo Tews

  • Posted in Nat Chem Biol, Publications
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Designed cell consortia as fragrance-programmable analog-to-digital converters

January 16th, 2017 by Marius Müller

Nature Chemical Biology 13, 309 (2017). doi:10.1038/nchembio.2281

Authors: Marius Müller, Simon Ausländer, Andrea Spinnler, David Ausländer, Julian Sikorski, Marc Folcher & Martin Fussenegger

  • Posted in Nat Chem Biol, Publications
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Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors

January 16th, 2017 by Ely B Porter

Nature Chemical Biology 13, 295 (2017). doi:10.1038/nchembio.2278

Authors: Ely B Porter, Jacob T Polaski, Makenna M Morck & Robert T Batey

  • Posted in Nat Chem Biol, Publications
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