Susan Lindquist (1949–2016)

January 19th, 2017 by Tricia R Serio

Nature Chemical Biology 13, 127 (2017). doi:10.1038/nchembio.2305

Author: Tricia R Serio

Susan Lindquist passed away on 27 October 2016, far too early for those who marveled at her brilliance through her many contributions to science, for all who knew her directly, and especially for her former trainees.

RNA modification: Reading Sex-lethal

January 19th, 2017 by Grant Miura

Nature Chemical Biology 13, 129 (2017). doi:10.1038/nchembio.2291

Author: Grant Miura

Nitrogenase: A fuel-producing microbe

January 19th, 2017 by Holger Dobbek

Nature Chemical Biology 13, 134 (2017). doi:10.1038/nchembio.2288

Author: Holger Dobbek

Nitrogenase has the canonical ability to reduce N2 to NH3, but under certain conditions, either in vitro or in vivo, it has the additional capability to convert CO2 to CO and CO to light hydrocarbons.

Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors

January 16th, 2017 by Ely B Porter

Nature Chemical Biology 13, 295 (2017). doi:10.1038/nchembio.2278

Authors: Ely B Porter, Jacob T Polaski, Makenna M Morck & Robert T Batey

  • Posted in Nat Chem Biol, Publications
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Chemical proteomics reveals ADP-ribosylation of small GTPases during oxidative stress

January 16th, 2017 by Nathan P Westcott

Nature Chemical Biology 13, 302 (2017). doi:10.1038/nchembio.2280

Authors: Nathan P Westcott, Joseph P Fernandez, Henrik Molina & Howard C Hang

  • Posted in Nat Chem Biol, Publications
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Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis

January 16th, 2017 by Matthew J Rodrigues

Nature Chemical Biology 13, 290 (2017). doi:10.1038/nchembio.2273

Authors: Matthew J Rodrigues, Volker Windeisen, Yang Zhang, Gabriela Guédez, Stefan Weber, Marco Strohmeier, Jeremiah W Hanes, Antoine Royant, Gwyndaf Evans, Irmgard Sinning, Steven E Ealick, Tadhg P Begley & Ivo Tews

  • Posted in Nat Chem Biol, Publications
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Designed cell consortia as fragrance-programmable analog-to-digital converters

January 16th, 2017 by Marius Müller

Nature Chemical Biology 13, 309 (2017). doi:10.1038/nchembio.2281

Authors: Marius Müller, Simon Ausländer, Andrea Spinnler, David Ausländer, Julian Sikorski, Marc Folcher & Martin Fussenegger

  • Posted in Nat Chem Biol, Publications
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Structural and functional insights into asymmetric enzymatic dehydration of alkenols

January 9th, 2017 by Bettina M Nestl

Nature Chemical Biology 13, 275 (2017). doi:10.1038/nchembio.2271

Authors: Bettina M Nestl, Christopher Geinitz, Stephanie Popa, Sari Rizek, Robert J Haselbeck, Rosary Stephen, Michael A Noble, Max-Philipp Fischer, Erik C Ralph, Hoi Ting Hau, Henry Man, Muhiadin Omar, Johan P Turkenburg, Stephen van Dien, Stephanie J Culler, Gideon Grogan & Bernhard Hauer

  • Posted in Nat Chem Biol, Publications
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Biomimetic spinning of artificial spider silk from a chimeric minispidroin

January 9th, 2017 by Marlene Andersson

Nature Chemical Biology 13, 262 (2017). doi:10.1038/nchembio.2269

Authors: Marlene Andersson, Qiupin Jia, Ana Abella, Xiau-Yeen Lee, Michael Landreh, Pasi Purhonen, Hans Hebert, Maria Tenje, Carol V Robinson, Qing Meng, Gustavo R Plaza, Jan Johansson & Anna Rising

Herein we present a chimeric recombinant spider silk protein (spidroin) whose aqueous solubility equals that of native spider silk dope and a spinning device that is based solely on aqueous buffers, shear forces and lowered pH. The process recapitulates the complex molecular mechanisms that dictate native spider silk spinning and is highly efficient; spidroin from one liter of bacterial shake-flask culture is enough to spin a kilometer of the hitherto toughest as-spun artificial spider silk fiber.

  • Posted in Nat Chem Biol, Publications
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Visualizing the secondary and tertiary architectural domains of lncRNA RepA

January 9th, 2017 by Fei Liu

Nature Chemical Biology 13, 282 (2017). doi:10.1038/nchembio.2272

Authors: Fei Liu, Srinivas Somarowthu & Anna Marie Pyle

  • Posted in Nat Chem Biol, Publications
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