Erratum: A Vibrio cholerae autoinducer–receptor pair that controls biofilm formation

September 19th, 2017 by Kai Papenfort

Nature Chemical Biology 13, 1137 (2017). doi:10.1038/nchembio1017-1137b

Author: Kai Papenfort, Justin E Silpe, Kelsey R Schramma, Jian-Ping Cong, Mohammad R Seyedsayamdost & Bonnie L Bassler

  • Posted in Nat Chem Biol, Publications
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Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel

August 28th, 2017 by Mikhail Metelev

Nature Chemical Biology 13, 1129 (2017). doi:10.1038/nchembio.2462

Authors: Mikhail Metelev, Ilya A Osterman, Dmitry Ghilarov, Nelli F Khabibullina, Alexander Yakimov, Konstantin Shabalin, Irina Utkina, Dmitry Y Travin, Ekaterina S Komarova, Marina Serebryakova, Tatyana Artamonova, Mikhail Khodorkovskii, Andrey L Konevega, Petr V Sergiev, Konstantin Severinov & Yury S Polikanov

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Oxidative cleavage of polysaccharides by monocopper enzymes depends on H2O2

August 28th, 2017 by Bastien Bissaro

Nature Chemical Biology 13, 1123 (2017). doi:10.1038/nchembio.2470

Authors: Bastien Bissaro, Åsmund K Røhr, Gerdt Müller, Piotr Chylenski, Morten Skaugen, Zarah Forsberg, Svein J Horn, Gustav Vaaje-Kolstad & Vincent G H Eijsink

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Metals induce transient folding and activation of the twister ribozyme

August 21st, 2017 by Subrata Panja

Nature Chemical Biology 13, 1109 (2017). doi:10.1038/nchembio.2459

Authors: Subrata Panja, Boyang Hua, Diego Zegarra, Taekjip Ha & Sarah A Woodson

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Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529

August 21st, 2017 by Marie Pancera

Nature Chemical Biology 13, 1115 (2017). doi:10.1038/nchembio.2460

Authors: Marie Pancera, Yen-Ting Lai, Tatsiana Bylund, Aliaksandr Druz, Sandeep Narpala, Sijy O'Dell, Arne Schön, Robert T Bailer, Gwo-Yu Chuang, Hui Geng, Mark K Louder, Reda Rawi, Djade I Soumana, Andrés Finzi, Alon Herschhorn, Navid Madani, Joseph Sodroski, Ernesto Freire, David R Langley, John R Mascola, Adrian B McDermott & Peter D Kwong

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Protein design: I like to fold it, fold it

August 18th, 2017 by Caitlin Deane

Nature Chemical Biology 13, 923 (2017). doi:10.1038/nchembio.2467

Author: Caitlin Deane

Neurobiology: Lighting up neurons

August 18th, 2017 by Grant Miura

Nature Chemical Biology 13, 923 (2017). doi:10.1038/nchembio.2469

Author: Grant Miura

Bacterial immunity: A virtuous CRISPR cycle

August 18th, 2017 by Terry L. Sheppard

Nature Chemical Biology 13, 923 (2017). doi:10.1038/nchembio.2468

Author: Terry L. Sheppard

Drug development: Locking down metabolism

August 18th, 2017 by William R Bishai

Nature Chemical Biology 13, 925 (2017). doi:10.1038/nchembio.2452

Author: William R Bishai

An allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase—an enzyme that is nonessential for in vitro growth—has potent antimicrobial activity, revealing a potentially expanded target list for antimicrobials and greater chemical space for new inhibitors.

A kinetic view of GPCR allostery and biased agonism

August 18th, 2017 by J Robert Lane

Nature Chemical Biology 13, 929 (2017). doi:10.1038/nchembio.2431

Authors: J Robert Lane, Lauren T May, Robert G Parton, Patrick M Sexton & Arthur Christopoulos