SAM/SAH Analogs as Versatile Tools for SAM-Dependent Methyltransferases

November 16th, 2015 by Jing Zhang and Yujun George Zheng

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00812

Structural Chemistry of Human RNA Methyltransferases

November 13th, 2015 by Matthieu Schapira

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00781

First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-Replicating M. tuberculosis

November 11th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00517
  • Posted in ACS Chemical Biology, Publications
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Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

November 11th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00895

[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction

November 10th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00513
  • Posted in ACS Chemical Biology, Publications
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Switching the Regioselectivity of a Cyclohexanone Monooxygenase toward (+)-trans-Dihydrocarvone by Rational Protein Design

November 9th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00723
  • Posted in ACS Chemical Biology, Publications
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PDZ-Reactive Peptide Activates Ephrin-B Reverse Signaling and Inhibits Neuronal Chemotaxis

November 9th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00889

Small Molecule Microarrays Enable the Identification of a Selective, Quadruplex-Binding Inhibitor of MYC Expression

November 6th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00577
  • Posted in ACS Chemical Biology, Publications
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Conversion of a Single Polypharmacological Agent into Selective Bivalent Inhibitors of Intracellular Kinase Activity

November 6th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00847
  • Posted in ACS Chemical Biology, Publications
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Self-Assembling NanoLuc Luciferase Fragments as Probes for Protein Aggregation in Living Cells

November 6th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00758