De Novo Design of Self-Assembling Foldamers That Inhibit Heparin–Protein Interactions

February 11th, 2014 by Geronda L. Montalvo, Yao Zhang, Trevor M. Young, Michael J. Costanzo, Katie B. Freeman, Jun Wang, Dylan J. Clements, Emma Magavern, Robert W. Kavash, Richard W. Scott, Dahui Liu and William F. DeGrado

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500026x

Heparinoids Activate a Protease, Secreted by Mucosa and Tumors, via Tethering Supplemented by Allostery

February 10th, 2014 by Yan G. Fulcher, Raghavendar Reddy Sanganna Gari, Nathan C. Frey, Fuming Zhang, Robert J. Linhardt, Gavin M. King and Steven R. Van Doren

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400898t
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Heparinoids Activate a Protease, Secreted by Mucosa and Tumors, via Tethering Supplemented by Allostery

Novel Inhibitors of Human DOPA Decarboxylase Extracted from Euonymus glabra Roxb.

February 10th, 2014 by Jie Ren, Yuanyuan Zhang, Huizi Jin, Jing Yu, Yueyang Zhou, Fang Wu and Weidong Zhang

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500009r

Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component

February 6th, 2014 by Felix Broecker, Jonas Aretz, You Yang, Jonas Hanske, Xiaoqiang Guo, Anika Reinhardt, Annette Wahlbrink, Christoph Rademacher, Chakkumkal Anish and Peter H. Seeberger

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400925k
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component

Unsaturated Macrocyclic Dihydroxamic Acid Siderophores Produced by Shewanella putrefaciens Using Precursor-Directed Biosynthesis

February 5th, 2014 by Cho Z. Soe and Rachel Codd

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400901j
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Unsaturated Macrocyclic Dihydroxamic Acid Siderophores Produced by Shewanella putrefaciens Using Precursor-Directed Biosynthesis

Characterization of Intracellular Regions in the Human Serotonin Transporter for Phosphorylation Sites

February 3rd, 2014 by Lena Sørensen, Kristian Strømgaard and Anders S. Kristensen

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb4007198
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Characterization of Intracellular Regions in the Human Serotonin Transporter for Phosphorylation Sites

Finding the Right (Bioorthogonal) Chemistry

January 30th, 2014 by David M. Patterson, Lidia A. Nazarova and Jennifer A. Prescher

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400828a

Structure Determinants for the Substrate Specificity of Acyl-CoA Δ9 Desaturases from a Marine Copepod

January 29th, 2014 by Dauenpen Meesapyodsuk and Xiao Qiu

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400675d
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Structure Determinants for the Substrate Specificity of Acyl-CoA Δ9 Desaturases from a Marine Copepod

A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red

January 29th, 2014 by Efthymia Prifti, Luc Reymond, Miwa Umebayashi, Ruud Hovius, Howard Riezman and Kai Johnsson

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400819c
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red

A FluoPol-ABPP PAD2 High-Throughput Screen Identifies the First Calcium Site Inhibitor Targeting the PADs

January 27th, 2014 by Daniel M. Lewallen, Kevin L. Bicker, Franck Madoux, Peter Chase, Lynne Anguish, Scott Coonrod, Peter Hodder and Paul R. Thompson

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400841k
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on A FluoPol-ABPP PAD2 High-Throughput Screen Identifies the First Calcium Site Inhibitor Targeting the PADs