A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red

January 29th, 2014 by Efthymia Prifti, Luc Reymond, Miwa Umebayashi, Ruud Hovius, Howard Riezman and Kai Johnsson

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400819c
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on A Fluorogenic Probe for SNAP-Tagged Plasma Membrane Proteins Based on the Solvatochromic Molecule Nile Red

A FluoPol-ABPP PAD2 High-Throughput Screen Identifies the First Calcium Site Inhibitor Targeting the PADs

January 27th, 2014 by Daniel M. Lewallen, Kevin L. Bicker, Franck Madoux, Peter Chase, Lynne Anguish, Scott Coonrod, Peter Hodder and Paul R. Thompson

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400841k
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on A FluoPol-ABPP PAD2 High-Throughput Screen Identifies the First Calcium Site Inhibitor Targeting the PADs

Genetic Incorporation of Seven ortho-Substituted Phenylalanine Derivatives

January 26th, 2014 by Jeffery M. Tharp, Yane-Shih Wang, Yan-Jiun Lee, Yanyan Yang and Wenshe R. Liu

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400917a

Role of tRNA Orthogonality in an Expanded Genetic Code

January 23rd, 2014 by Tsotne Javahishvili, Anthony Manibusan, Shaila Srinagesh, Darin Lee, Semsi Ensari, Mark Shimazu and Peter G. Schultz

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb4005172

Molecular Vehicles for Mitochondrial Chemical Biology and Drug Delivery

January 23rd, 2014 by Sae Rin Jean, David V. Tulumello, Simon P. Wisnovsky, Eric K. Lei, Mark P. Pereira and Shana O. Kelley

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400821p

Proteomic Profiling of Nitrosative Stress: Protein S-Oxidation Accompanies S-Nitrosylation

January 21st, 2014 by Yue-Ting Wang, Sujeewa C. Piyankarage, David L. Williams and Gregory R. J. Thatcher

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400547u

Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides

January 21st, 2014 by Yuxiao Wang, Tienhuei G. Ho, Daniela Bertinetti, Matthias Neddermann, Eugen Franz, Gary C. H. Mo, Lewis P. Schendowich, Avinash Sukhu, Raybun C. Spelts, Jin Zhang, Friedrich W. Herberg and Eileen J. Kennedy

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400900r

Actin Controls the Vesicular Fraction of Dopamine Released During Extended Kiss and Run Exocytosis

January 20th, 2014 by Raphaël Trouillon and Andrew G. Ewing

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400665f
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Actin Controls the Vesicular Fraction of Dopamine Released During Extended Kiss and Run Exocytosis

NMR Structure of the S-Linked Glycopeptide Sublancin 168

January 17th, 2014 by Chantal V. Garcia De Gonzalo, Lingyang Zhu, Trent J. Oman and Wilfred A. van der Donk

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb4008106

Discovery of Highly Potent p53-MDM2 Antagonists and Structural Basis for Anti-Acute Myeloid Leukemia Activities

January 17th, 2014 by Yijun Huang, Siglinde Wolf, Barbara Beck, Lisa-Maria Köhler, Kareem Khoury, Grzegorz M. Popowicz, Sayed K Goda, Marion Subklewe, Aleksandra Twarda, Tad A. Holak and Alexander Dömling

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb400728e
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Discovery of Highly Potent p53-MDM2 Antagonists and Structural Basis for Anti-Acute Myeloid Leukemia Activities