Potent and Selective Small-Molecule Inhibitors of cIAP1/2 Proteins Reveal That the Binding of Smac Mimetics to XIAP BIR3 Is Not Required for Their Effective Induction of Cell Death in Tumor Cells

February 12th, 2014 by Haiying Sun, Jianfeng Lu, Liu Liu, Chao-Yie Yang and Shaomeng Wang

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ACS Chemical Biology
DOI: 10.1021/cb400889a
  • Posted in ACS Chemical Biology, Publications
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Cruentaren A Binds F1F0 ATP Synthase To Modulate the Hsp90 Protein Folding Machinery

February 12th, 2014 by Jessica A. Hall, Bhaskar Reddy Kusuma, Gary E. L. Brandt and Brian S. J. Blagg

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ACS Chemical Biology
DOI: 10.1021/cb400906e

De Novo Design of Self-Assembling Foldamers That Inhibit Heparin–Protein Interactions

February 11th, 2014 by Geronda L. Montalvo, Yao Zhang, Trevor M. Young, Michael J. Costanzo, Katie B. Freeman, Jun Wang, Dylan J. Clements, Emma Magavern, Robert W. Kavash, Richard W. Scott, Dahui Liu and William F. DeGrado

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ACS Chemical Biology
DOI: 10.1021/cb500026x

Heparinoids Activate a Protease, Secreted by Mucosa and Tumors, via Tethering Supplemented by Allostery

February 10th, 2014 by Yan G. Fulcher, Raghavendar Reddy Sanganna Gari, Nathan C. Frey, Fuming Zhang, Robert J. Linhardt, Gavin M. King and Steven R. Van Doren

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ACS Chemical Biology
DOI: 10.1021/cb400898t
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Novel Inhibitors of Human DOPA Decarboxylase Extracted from Euonymus glabra Roxb.

February 10th, 2014 by Jie Ren, Yuanyuan Zhang, Huizi Jin, Jing Yu, Yueyang Zhou, Fang Wu and Weidong Zhang

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ACS Chemical Biology
DOI: 10.1021/cb500009r

Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component

February 6th, 2014 by Felix Broecker, Jonas Aretz, You Yang, Jonas Hanske, Xiaoqiang Guo, Anika Reinhardt, Annette Wahlbrink, Christoph Rademacher, Chakkumkal Anish and Peter H. Seeberger

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ACS Chemical Biology
DOI: 10.1021/cb400925k
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Unsaturated Macrocyclic Dihydroxamic Acid Siderophores Produced by Shewanella putrefaciens Using Precursor-Directed Biosynthesis

February 5th, 2014 by Cho Z. Soe and Rachel Codd

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ACS Chemical Biology
DOI: 10.1021/cb400901j
  • Posted in ACS Chemical Biology, Publications
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Characterization of Intracellular Regions in the Human Serotonin Transporter for Phosphorylation Sites

February 3rd, 2014 by Lena Sørensen, Kristian Strømgaard and Anders S. Kristensen

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ACS Chemical Biology
DOI: 10.1021/cb4007198
  • Posted in ACS Chemical Biology, Publications
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Finding the Right (Bioorthogonal) Chemistry

January 30th, 2014 by David M. Patterson, Lidia A. Nazarova and Jennifer A. Prescher

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ACS Chemical Biology
DOI: 10.1021/cb400828a

Structure Determinants for the Substrate Specificity of Acyl-CoA Δ9 Desaturases from a Marine Copepod

January 29th, 2014 by Dauenpen Meesapyodsuk and Xiao Qiu

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ACS Chemical Biology
DOI: 10.1021/cb400675d
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