Further Insights into the Effects of Pre-organizing the BimBH3 Helix

February 18th, 2014 by Toru Okamoto, David Segal, Kerry Zobel, Anna Fedorova, Hong Yang, Wayne J. Fairbrother, David C. S. Huang, Brian J. Smith, Kurt Deshayes and Peter E. Czabotar

ACS Chemical Biology
DOI: 10.1021/cb400638p

Protein Kinase Cδ Is a Therapeutic Target in Malignant Melanoma with NRAS Mutation

February 18th, 2014 by Asami Takashima, Brandon English, Zhihong Chen, Juxiang Cao, Rutao Cui, Robert M. Williams and Douglas V. Faller

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ACS Chemical Biology
DOI: 10.1021/cb400837t

Correction to Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

February 14th, 2014 by Hyung-Gu Kim, Li Tan, Ellen L. Weisberg, Feiyang Liu, Peter Canning, Hwan-Geun Choi, Scott Ezell, Zheng Zhao, Hong Wu, Jinhua Wang, Anna Mandinova, Alex N. Bullock, Qingsong Liu, Sam W. Lee and Nathanael S. Gray

ACS Chemical Biology
DOI: 10.1021/cb5000949

Potent and Selective Small-Molecule Inhibitors of cIAP1/2 Proteins Reveal That the Binding of Smac Mimetics to XIAP BIR3 Is Not Required for Their Effective Induction of Cell Death in Tumor Cells

February 12th, 2014 by Haiying Sun, Jianfeng Lu, Liu Liu, Chao-Yie Yang and Shaomeng Wang

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ACS Chemical Biology
DOI: 10.1021/cb400889a
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Cruentaren A Binds F1F0 ATP Synthase To Modulate the Hsp90 Protein Folding Machinery

February 12th, 2014 by Jessica A. Hall, Bhaskar Reddy Kusuma, Gary E. L. Brandt and Brian S. J. Blagg

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ACS Chemical Biology
DOI: 10.1021/cb400906e

De Novo Design of Self-Assembling Foldamers That Inhibit Heparin–Protein Interactions

February 11th, 2014 by Geronda L. Montalvo, Yao Zhang, Trevor M. Young, Michael J. Costanzo, Katie B. Freeman, Jun Wang, Dylan J. Clements, Emma Magavern, Robert W. Kavash, Richard W. Scott, Dahui Liu and William F. DeGrado

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ACS Chemical Biology
DOI: 10.1021/cb500026x

Heparinoids Activate a Protease, Secreted by Mucosa and Tumors, via Tethering Supplemented by Allostery

February 10th, 2014 by Yan G. Fulcher, Raghavendar Reddy Sanganna Gari, Nathan C. Frey, Fuming Zhang, Robert J. Linhardt, Gavin M. King and Steven R. Van Doren

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ACS Chemical Biology
DOI: 10.1021/cb400898t
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Novel Inhibitors of Human DOPA Decarboxylase Extracted from Euonymus glabra Roxb.

February 10th, 2014 by Jie Ren, Yuanyuan Zhang, Huizi Jin, Jing Yu, Yueyang Zhou, Fang Wu and Weidong Zhang

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ACS Chemical Biology
DOI: 10.1021/cb500009r

Epitope Recognition of Antibodies against a Yersinia pestis Lipopolysaccharide Trisaccharide Component

February 6th, 2014 by Felix Broecker, Jonas Aretz, You Yang, Jonas Hanske, Xiaoqiang Guo, Anika Reinhardt, Annette Wahlbrink, Christoph Rademacher, Chakkumkal Anish and Peter H. Seeberger

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ACS Chemical Biology
DOI: 10.1021/cb400925k
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Unsaturated Macrocyclic Dihydroxamic Acid Siderophores Produced by Shewanella putrefaciens Using Precursor-Directed Biosynthesis

February 5th, 2014 by Cho Z. Soe and Rachel Codd

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ACS Chemical Biology
DOI: 10.1021/cb400901j
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