Imparting Albumin-Binding Affinity to a Human Protein by Mimicking the Contact Surface of a Bacterial Binding Protein

February 26th, 2014 by Satoshi Oshiro and Shinya Honda

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ACS Chemical Biology
DOI: 10.1021/cb400946m
  • Posted in ACS Chemical Biology, Publications
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Efficient Nuclear DNA Cleavage in Human Cancer Cells by Synthetic Bleomycin Mimics

February 26th, 2014 by Qian Li, Monique G.P. van der Wijst, Hinke G. Kazemier, Marianne G. Rots and Gerard Roelfes

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ACS Chemical Biology
DOI: 10.1021/cb500057n

Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches

February 25th, 2014 by Angeles Canales, Lidia Nieto, Javier Rodríguez-Salarichs, Pedro A. Sánchez-Murcia, Claire Coderch, Alvaro Cortés-Cabrera, Ian Paterson, Teresa Carlomagno, Federico Gago, José M. Andreu, Karl-Heinz Altmann, Jesús Jiménez-Barbero and J. Fernando

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ACS Chemical Biology
DOI: 10.1021/cb400673h
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Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis

February 21st, 2014 by Adam D. Daniels, Ivan Campeotto, Marc W. van der Kamp, Amanda H. Bolt, Chi H. Trinh, Simon E. V. Phillips, Arwen R. Pearson, Adam Nelson, Adrian J. Mulholland and Alan Berry

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ACS Chemical Biology
DOI: 10.1021/cb500067z
  • Posted in ACS Chemical Biology, Publications
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Identification of a New Class of Small Molecules That Efficiently Reactivate Latent Epstein–Barr Virus

February 19th, 2014 by Nadezhda Tikhmyanova, David C. Schultz, Theresa Lee, Joseph M. Salvino and Paul M. Lieberman

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ACS Chemical Biology
DOI: 10.1021/cb4006326
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Targeting the r(CGG) Repeats That Cause FXTAS with Modularly Assembled Small Molecules and Oligonucleotides

February 19th, 2014 by Tuan Tran, Jessica L. Childs-Disney, Biao Liu, Lirui Guan, Suzanne Rzuczek and Matthew D. Disney

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ACS Chemical Biology
DOI: 10.1021/cb400875u
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Antiviral Activity of an Isatin Derivative via Induction of PERK-Nrf2-Mediated Suppression of Cap-Independent Translation

February 18th, 2014 by Huifang M. Zhang, Huanqin Dai, Paul J. Hanson, Huidong Li, Hui Guo, Xin Ye, Maged G. Hemida, Luoqiang Wang, Yaojun Tong, Ye Qiu, Selina Liu, Fengping Wang, Fuhang Song, Buchang Zhang, Jian-Guo Wang, Li-Xin Zhang and Decheng Yang

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ACS Chemical Biology
DOI: 10.1021/cb400775z
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Further Insights into the Effects of Pre-organizing the BimBH3 Helix

February 18th, 2014 by Toru Okamoto, David Segal, Kerry Zobel, Anna Fedorova, Hong Yang, Wayne J. Fairbrother, David C. S. Huang, Brian J. Smith, Kurt Deshayes and Peter E. Czabotar

ACS Chemical Biology
DOI: 10.1021/cb400638p

Protein Kinase Cδ Is a Therapeutic Target in Malignant Melanoma with NRAS Mutation

February 18th, 2014 by Asami Takashima, Brandon English, Zhihong Chen, Juxiang Cao, Rutao Cui, Robert M. Williams and Douglas V. Faller

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ACS Chemical Biology
DOI: 10.1021/cb400837t

Correction to Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

February 14th, 2014 by Hyung-Gu Kim, Li Tan, Ellen L. Weisberg, Feiyang Liu, Peter Canning, Hwan-Geun Choi, Scott Ezell, Zheng Zhao, Hong Wu, Jinhua Wang, Anna Mandinova, Alex N. Bullock, Qingsong Liu, Sam W. Lee and Nathanael S. Gray

ACS Chemical Biology
DOI: 10.1021/cb5000949