Insights into the Biosynthesis of 12-Membered Resorcylic Acid Lactones from Heterologous Production in Saccharomyces cerevisiae

March 6th, 2014 by Yuquan Xu, Tong Zhou, Patricia Espinosa-Artiles, Ying Tang, Jixun Zhan and István Molnár

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ACS Chemical Biology
DOI: 10.1021/cb500043g
  • Posted in ACS Chemical Biology, Publications
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Selective Ligand Behaviors Provide New Insights into Agonist Activation of Nicotinic Acetylcholine Receptors

March 5th, 2014 by Christopher B. Marotta, Iva Rreza, Henry A. Lester and Dennis A. Dougherty

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ACS Chemical Biology
DOI: 10.1021/cb400937d
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A Key n→π* Interaction in N-Acyl Homoserine Lactones

February 26th, 2014 by Robert W. Newberry and Ronald T. Raines

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ACS Chemical Biology
DOI: 10.1021/cb500022u

Imparting Albumin-Binding Affinity to a Human Protein by Mimicking the Contact Surface of a Bacterial Binding Protein

February 26th, 2014 by Satoshi Oshiro and Shinya Honda

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ACS Chemical Biology
DOI: 10.1021/cb400946m
  • Posted in ACS Chemical Biology, Publications
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Efficient Nuclear DNA Cleavage in Human Cancer Cells by Synthetic Bleomycin Mimics

February 26th, 2014 by Qian Li, Monique G.P. van der Wijst, Hinke G. Kazemier, Marianne G. Rots and Gerard Roelfes

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ACS Chemical Biology
DOI: 10.1021/cb500057n

Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches

February 25th, 2014 by Angeles Canales, Lidia Nieto, Javier Rodríguez-Salarichs, Pedro A. Sánchez-Murcia, Claire Coderch, Alvaro Cortés-Cabrera, Ian Paterson, Teresa Carlomagno, Federico Gago, José M. Andreu, Karl-Heinz Altmann, Jesús Jiménez-Barbero and J. Fernando

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ACS Chemical Biology
DOI: 10.1021/cb400673h
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Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, QM/MM Simulation, and Mutagenesis

February 21st, 2014 by Adam D. Daniels, Ivan Campeotto, Marc W. van der Kamp, Amanda H. Bolt, Chi H. Trinh, Simon E. V. Phillips, Arwen R. Pearson, Adam Nelson, Adrian J. Mulholland and Alan Berry

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ACS Chemical Biology
DOI: 10.1021/cb500067z
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Identification of a New Class of Small Molecules That Efficiently Reactivate Latent Epstein–Barr Virus

February 19th, 2014 by Nadezhda Tikhmyanova, David C. Schultz, Theresa Lee, Joseph M. Salvino and Paul M. Lieberman

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ACS Chemical Biology
DOI: 10.1021/cb4006326
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Targeting the r(CGG) Repeats That Cause FXTAS with Modularly Assembled Small Molecules and Oligonucleotides

February 19th, 2014 by Tuan Tran, Jessica L. Childs-Disney, Biao Liu, Lirui Guan, Suzanne Rzuczek and Matthew D. Disney

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ACS Chemical Biology
DOI: 10.1021/cb400875u
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Antiviral Activity of an Isatin Derivative via Induction of PERK-Nrf2-Mediated Suppression of Cap-Independent Translation

February 18th, 2014 by Huifang M. Zhang, Huanqin Dai, Paul J. Hanson, Huidong Li, Hui Guo, Xin Ye, Maged G. Hemida, Luoqiang Wang, Yaojun Tong, Ye Qiu, Selina Liu, Fengping Wang, Fuhang Song, Buchang Zhang, Jian-Guo Wang, Li-Xin Zhang and Decheng Yang

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ACS Chemical Biology
DOI: 10.1021/cb400775z
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