Identification and Characterization of an Allosteric Inhibitory Site on Dihydropteroate Synthase

March 27th, 2014 by Dalia I. Hammoudeh, Mihir Daté, Mi-Kyung Yun, Weixing Zhang, Vincent A. Boyd, Ariele Viacava Follis, Elizabeth Griffith, Richard E. Lee, Donald Bashford and Stephen W. White

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ACS Chemical Biology
DOI: 10.1021/cb500038g

Expanded Cellular Amino Acid Pools Containing Phosphoserine, Phosphothreonine, and Phosphotyrosine

March 27th, 2014 by Justin B. Steinfeld, Hans R. Aerni, Svetlana Rogulina, Yuchen Liu and Jesse Rinehart

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ACS Chemical Biology
DOI: 10.1021/cb5000532
  • Posted in ACS Chemical Biology, Publications
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Synthetic RNA Recognition Motifs That Selectively Recognize HIV-1 Trans-Activation Response Element Hairpin RNA

March 25th, 2014 by Brett D. Blakeley and Brian R. McNaughton

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ACS Chemical Biology
DOI: 10.1021/cb500138h
  • Posted in ACS Chemical Biology, Publications
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Mito-DCA: A Mitochondria Targeted Molecular Scaffold for Efficacious Delivery of Metabolic Modulator Dichloroacetate

March 25th, 2014 by Rakesh K. Pathak, Sean Marrache, Donald A. Harn and Shanta Dhar

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ACS Chemical Biology
DOI: 10.1021/cb400944y
  • Posted in ACS Chemical Biology, Publications
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Optical Control of the Ca2+ Concentration in a Live Specimen with a Genetically Encoded Ca2+-Releasing Molecular Tool

March 24th, 2014 by Noritaka Fukuda, Tomoki Matsuda and Takeharu Nagai

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ACS Chemical Biology
DOI: 10.1021/cb400849n
  • Posted in ACS Chemical Biology, Publications
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A Small Molecule Compound Targeting STAT3 DNA-Binding Domain Inhibits Cancer Cell Proliferation, Migration, and Invasion

March 24th, 2014 by Wei Huang, Zizheng Dong, Fang Wang, Hui Peng, Jing-Yuan Liu and Jian-Ting Zhang

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ACS Chemical Biology
DOI: 10.1021/cb500071v
  • Posted in ACS Chemical Biology, Publications
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Bright Building Blocks for Chemical Biology

March 20th, 2014 by Luke D. Lavis and Ronald T. Raines

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ACS Chemical Biology
DOI: 10.1021/cb500078u

Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

March 17th, 2014 by Tony Velkov, Kade D. Roberts, Roger L. Nation, Jiping Wang, Philip E. Thompson and Jian Li

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ACS Chemical Biology
DOI: 10.1021/cb500080r
  • Posted in ACS Chemical Biology, Publications
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Discovery of a Potent, Covalent BTK Inhibitor for B-Cell Lymphoma

March 17th, 2014 by Hong Wu, Wenchao Wang, Feiyang Liu, Ellen E. Weisberg, Bei Tian, Yongfei Chen, Binhua Li, Aoli Wang, Beilei Wang, Zheng Zhao, Douglas W. McMillin, Chen Hu, Hong Li, Jinhua Wang, Yanke Liang, Sara J. Buhrlage, Junting Liang, Jing Liu, Guang Yang, Jenn

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ACS Chemical Biology
DOI: 10.1021/cb4008524

Genetic Incorporation of Histidine Derivatives Using an Engineered Pyrrolysyl-tRNA Synthetase

March 17th, 2014 by Han Xiao, Francis B. Peters, Peng-Yu Yang, Sean Reed, Johnathan R. Chittuluru and Peter G. Schultz

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ACS Chemical Biology
DOI: 10.1021/cb500032c