A Small Molecule Compound Targeting STAT3 DNA-Binding Domain Inhibits Cancer Cell Proliferation, Migration, and Invasion

March 24th, 2014 by Wei Huang, Zizheng Dong, Fang Wang, Hui Peng, Jing-Yuan Liu and Jian-Ting Zhang

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ACS Chemical Biology
DOI: 10.1021/cb500071v
  • Posted in ACS Chemical Biology, Publications
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Bright Building Blocks for Chemical Biology

March 20th, 2014 by Luke D. Lavis and Ronald T. Raines

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ACS Chemical Biology
DOI: 10.1021/cb500078u

Teaching ‘Old’ Polymyxins New Tricks: New-Generation Lipopeptides Targeting Gram-Negative ‘Superbugs’

March 17th, 2014 by Tony Velkov, Kade D. Roberts, Roger L. Nation, Jiping Wang, Philip E. Thompson and Jian Li

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ACS Chemical Biology
DOI: 10.1021/cb500080r
  • Posted in ACS Chemical Biology, Publications
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Discovery of a Potent, Covalent BTK Inhibitor for B-Cell Lymphoma

March 17th, 2014 by Hong Wu, Wenchao Wang, Feiyang Liu, Ellen E. Weisberg, Bei Tian, Yongfei Chen, Binhua Li, Aoli Wang, Beilei Wang, Zheng Zhao, Douglas W. McMillin, Chen Hu, Hong Li, Jinhua Wang, Yanke Liang, Sara J. Buhrlage, Junting Liang, Jing Liu, Guang Yang, Jenn

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ACS Chemical Biology
DOI: 10.1021/cb4008524

Genetic Incorporation of Histidine Derivatives Using an Engineered Pyrrolysyl-tRNA Synthetase

March 17th, 2014 by Han Xiao, Francis B. Peters, Peng-Yu Yang, Sean Reed, Johnathan R. Chittuluru and Peter G. Schultz

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ACS Chemical Biology
DOI: 10.1021/cb500032c

Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity

March 13th, 2014 by Catherine A. McLellan, Luke Whitesell, Oliver D. King, Alex K. Lancaster, Ralph Mazitschek and Susan Lindquist

ACS Chemical Biology
DOI: 10.1021/cb5000339
  • Posted in ACS Chemical Biology, Publications
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Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors

March 13th, 2014 by Stuart W. J. Ember, Jin-Yi Zhu, Sanne H. Olesen, Mathew P. Martin, Andreas Becker, Norbert Berndt, Gunda I. Georg and Ernst Schönbrunn

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ACS Chemical Biology
DOI: 10.1021/cb500072z
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Molecular Determinants of a Regulatory Prolyl Isomerization in the Signal Adapter Protein c-CrkII

March 10th, 2014 by Philipp A. M. Schmidpeter and Franz X. Schmid

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ACS Chemical Biology
DOI: 10.1021/cb500001n
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A Structural and Energetic Model for the Slow-Onset Inhibition of the Mycobacterium tuberculosis Enoyl-ACP Reductase InhA

March 10th, 2014 by Huei-Jiun Li, Cheng-Tsung Lai, Pan Pan, Weixuan Yu, Nina Liu, Gopal R. Bommineni, Miguel Garcia-Diaz, Carlos Simmerling and Peter J. Tonge

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ACS Chemical Biology
DOI: 10.1021/cb400896g
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Organophosphorus Flame Retardants Inhibit Specific Liver Carboxylesterases and Cause Serum Hypertriglyceridemia

March 10th, 2014 by Patrick J. Morris, Daniel Medina-Cleghorn, Ann Heslin, Sarah M. King, Joseph Orr, Melinda M. Mulvihill, Ronald M. Krauss and Daniel K. Nomura

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ACS Chemical Biology
DOI: 10.1021/cb500014r
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