Inositol Phosphate Recycling Regulates Glycolytic and Lipid Metabolism That Drives Cancer Aggressiveness

April 28th, 2014 by Daniel I. Benjamin, Sharon M. Louie, Melinda M. Mulvihill, Rebecca A. Kohnz, Daniel S. Li, Lauryn G. Chan, Antonio Sorrentino, Sourav Bandyopadhyay, Alyssa Cozzo, Anayo Ohiri, Andrei Goga, Shu-Wing Ng and Daniel K. Nomura

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb5001907
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Inositol Phosphate Recycling Regulates Glycolytic and Lipid Metabolism That Drives Cancer Aggressiveness

Gyramides Prevent Bacterial Growth by Inhibiting DNA Gyrase and Altering Chromosome Topology

April 22nd, 2014 by Manohary Rajendram, Katherine A. Hurley, Marie H. Foss, Kelsey M. Thornton, Jared T. Moore, Jared T. Shaw and Douglas B. Weibel

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500154m

Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

April 16th, 2014 by Lisa M. Ryno, Joseph C. Genereux, Tadasuke Naito, Richard I. Morimoto, Evan T. Powers, Matthew D. Shoulders and R. Luke Wiseman

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500062n
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1

Correction to Mutasynthesis of a Potent Anticancer Sibiromycin Analogue

April 14th, 2014 by Isaac T. Yonemoto, Wei Li, Ankush Khullar, Natàlia Reixach and Barbara Gerratana

ACS Chemical Biology
DOI: 10.1021/cb5002476

An Inhibitor’s-Eye View of the ATP-Binding Site of CDKs in Different Regulatory States

April 10th, 2014 by Aude Echalier, Alison J. Hole, Graziano Lolli, Jane A. Endicott and Martin E. M. Noble

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500135f

Noncovalent Spin Labeling of Riboswitch RNAs To Obtain Long-Range Structural NMR Restraints

April 9th, 2014 by Christina Helmling, Irene Bessi, Anna Wacker, Kai A. Schnorr, Hendrik R. A. Jonker, Christian Richter, Dominic Wagner, Michael Kreibich and Harald Schwalbe

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500050t

Peptide Formation by N-Methyl Amino Acids in Translation Is Hastened by Higher pH and tRNAPro

April 9th, 2014 by Jinfan Wang, Marek Kwiatkowski, Michael Y. Pavlov, Måns Ehrenberg and Anthony C. Forster

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500036a

A Selective Phenelzine Analogue Inhibitor of Histone Demethylase LSD1

April 6th, 2014 by Polina Prusevich, Jay H. Kalin, Shonoi A. Ming, Manuela Basso, Jeffrey Givens, Xin Li, Jianfei Hu, Martin S. Taylor, Anne M. Cieniewicz, Po-Yuan Hsiao, Rong Huang, Heather Roberson, Nkosi Adejola, Lindsay B. Avery, Robert A. Casero, Sean D. Taverna,

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500018s

X-ray Structures of Human Furin in Complex with Competitive Inhibitors

April 1st, 2014 by Sven O. Dahms, Kornelia Hardes, Gero L. Becker, Torsten Steinmetzer, Hans Brandstetter and Manuel E. Than

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500087x

Nav1.1 Modulation by a Novel Triazole Compound Attenuates Epileptic Seizures in Rodents

March 31st, 2014 by John Gilchrist, Stacey Dutton, Marcelo Diaz-Bustamante, Annie McPherson, Nicolas Olivares, Jeet Kalia, Andrew Escayg and Frank Bosmans

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500108p