Barrel-shaped ClpP Proteases Display Attenuated Cleavage Specificities

December 9th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00757

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

December 8th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00839
  • Posted in ACS Chemical Biology, Publications
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In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish

December 8th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00751
  • Posted in ACS Chemical Biology, Publications
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Small Molecule Targeting of a MicroRNA Associated with Hepatocellular Carcinoma

December 7th, 2015 by Jessica L. Childs-Disney and Matthew D. Disney

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00615

Reading between the Lines: “ADD”-ing Histone and DNA Methylation Marks toward a New Epigenetic “Sum”

December 7th, 2015 by Kyung-Min Noh, C. David Allis and Haitao Li

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00830
  • Posted in ACS Chemical Biology, Publications
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An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection

December 7th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00640
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Rational Design of a Dephosphorylation-Resistant Reporter Enables Single-Cell Measurement of Tyrosine Kinase Activity

December 4th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00667
  • Posted in ACS Chemical Biology, Publications
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Dynamic Docking of Conformationally Constrained Macrocycles: Methods and Applications

December 4th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00663

Copper and Zinc Ions Specifically Promote Nonamyloid Aggregation of the Highly Stable Human γ-D Crystallin

December 3rd, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00919
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Interrogating Endogenous Protein Phosphatase Activity with Rationally Designed Chemosensors

December 3rd, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00506