Fungal Polyketide Synthase Product Chain-Length Control by Partnering Thiohydrolase
May 29th, 2014 by Angelica O. Zabala, Yit-Heng Chooi, Moon Seok Choi, Hsiao-Ching Lin and Yi Tang
Discovery of Selective Ligands for Telomeric RNA G-quadruplexes (TERRA) through 19F-NMR Based Fragment Screening
May 28th, 2014 by Miguel Garavís, Blanca López-Méndez, Alvaro Somoza, Julen Oyarzabal, Claudio Dalvit, Alfredo Villasante, Ramón Campos-Olivas and Carlos González
ATP-Mediated Kinome Selectivity: The Missing Link in Understanding the Contribution of Individual JAK Kinase Isoforms to Cellular Signaling
May 27th, 2014 by Atli Thorarensen, Mary Ellen Banker, Andrew Fensome, Jean-Baptiste Telliez, Brian Juba, Fabien Vincent, Robert M. Czerwinski and Agustin Casimiro-Garcia
Automated Genome Mining of Ribosomal Peptide Natural Products
May 23rd, 2014 by Hosein Mohimani, Roland D. Kersten, Wei-Ting Liu, Mingxun Wang, Samuel O. Purvine, Si Wu, Heather M. Brewer, Ljiljana Pasa-Tolic, Nuno Bandeira, Bradley S. Moore, Pavel A. Pevzner and Pieter C. Dorrestein
Engineering a Light-Regulated GABAA Receptor for Optical Control of Neural Inhibition
May 22nd, 2014 by Wan-Chen Lin, Christopher M. Davenport, Alexandre Mourot, Devaiah Vytla, Caleb M. Smith, Kathryne A. Medeiros, James J. Chambers and Richard H. Kramer
Synthetic versus Natural Receptors: Supramolecular Control of Chemical Sensing in Fish
May 22nd, 2014 by José P. Da Silva, Rajib Choudhury, Mintu Porel, Uwe Pischel, Steffen Jockusch, Peter C. Hubbard, Vaidhyanathan Ramamurthy and Adelino V. M. Canário
Optical Control of Protein Function through Unnatural Amino Acid Mutagenesis and Other Optogenetic Approaches
May 21st, 2014 by Austin S. Baker and Alexander Deiters
Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine
May 21st, 2014 by Jacqueline M. Wurst, Eric J. Drake, Jimmy R. Theriault, Ivan T. Jewett, Lynn VerPlank, Jose R. Perez, Sivaraman Dandapani, Michelle Palmer, Samuel M. Moskowitz, Stuart L. Schreiber, Benito Munoz and Andrew M. Gulick
Increasing Chemical Space Coverage by Combining Empirical and Computational Fragment Screens
May 20th, 2014 by Sarah Barelier, Oliv Eidam, Inbar Fish, Johan Hollander, Francis Figaroa, Ruta Nachane, John J. Irwin, Brian K. Shoichet and Gregg Siegal
Structure–Function Relationship of Thiazolide-Induced Apoptosis in Colorectal Tumor Cells
May 19th, 2014 by Anette Brockmann, Tobias Strittmatter, Sarah May, Kerstin Stemmer, Andreas Marx and Thomas Brunner
