Automated Genome Mining of Ribosomal Peptide Natural Products

May 23rd, 2014 by Hosein Mohimani, Roland D. Kersten, Wei-Ting Liu, Mingxun Wang, Samuel O. Purvine, Si Wu, Heather M. Brewer, Ljiljana Pasa-Tolic, Nuno Bandeira, Bradley S. Moore, Pavel A. Pevzner and Pieter C. Dorrestein

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ACS Chemical Biology
DOI: 10.1021/cb500199h

Engineering a Light-Regulated GABAA Receptor for Optical Control of Neural Inhibition

May 22nd, 2014 by Wan-Chen Lin, Christopher M. Davenport, Alexandre Mourot, Devaiah Vytla, Caleb M. Smith, Kathryne A. Medeiros, James J. Chambers and Richard H. Kramer

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ACS Chemical Biology
DOI: 10.1021/cb500167u

Synthetic versus Natural Receptors: Supramolecular Control of Chemical Sensing in Fish

May 22nd, 2014 by José P. Da Silva, Rajib Choudhury, Mintu Porel, Uwe Pischel, Steffen Jockusch, Peter C. Hubbard, Vaidhyanathan Ramamurthy and Adelino V. M. Canário

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ACS Chemical Biology
DOI: 10.1021/cb500172u

Optical Control of Protein Function through Unnatural Amino Acid Mutagenesis and Other Optogenetic Approaches

May 21st, 2014 by Austin S. Baker and Alexander Deiters

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ACS Chemical Biology
DOI: 10.1021/cb500176x
  • Posted in ACS Chemical Biology, Publications
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Identification of Inhibitors of PvdQ, an Enzyme Involved in the Synthesis of the Siderophore Pyoverdine

May 21st, 2014 by Jacqueline M. Wurst, Eric J. Drake, Jimmy R. Theriault, Ivan T. Jewett, Lynn VerPlank, Jose R. Perez, Sivaraman Dandapani, Michelle Palmer, Samuel M. Moskowitz, Stuart L. Schreiber, Benito Munoz and Andrew M. Gulick

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ACS Chemical Biology
DOI: 10.1021/cb5001586
  • Posted in ACS Chemical Biology, Publications
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Increasing Chemical Space Coverage by Combining Empirical and Computational Fragment Screens

May 20th, 2014 by Sarah Barelier, Oliv Eidam, Inbar Fish, Johan Hollander, Francis Figaroa, Ruta Nachane, John J. Irwin, Brian K. Shoichet and Gregg Siegal

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ACS Chemical Biology
DOI: 10.1021/cb5001636

Structure–Function Relationship of Thiazolide-Induced Apoptosis in Colorectal Tumor Cells

May 19th, 2014 by Anette Brockmann, Tobias Strittmatter, Sarah May, Kerstin Stemmer, Andreas Marx and Thomas Brunner

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ACS Chemical Biology
DOI: 10.1021/cb500209a

Functionalization of β-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid System

May 15th, 2014 by Andrea Chicca, Diego Caprioglio, Alberto Minassi, Vanessa Petrucci, Giovanni Appendino, Orazio Taglialatela-Scafati and Jürg Gertsch

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ACS Chemical Biology
DOI: 10.1021/cb500177c
  • Posted in ACS Chemical Biology, Publications
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A Biosensor of Src Family Kinase Conformation by Exposable Tetracysteine Useful for Cell-Based Screening

May 15th, 2014 by Sevgi Irtegun, Rebecca Wood, Kurt Lackovic, Jörg Schweiggert, Yasmin M. Ramdzan, David C. S. Huang, Terrence D. Mulhern and Danny M. Hatters

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ACS Chemical Biology
DOI: 10.1021/cb500242q
  • Posted in ACS Chemical Biology, Publications
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Role of N-Linked Glycans in the Interactions of Recombinant HCV Envelope Glycoproteins with Cellular Receptors

May 15th, 2014 by Po-Chang Chen, Po-Kai Chuang, Chein-Hung Chen, Ya-Ting Chan, Juine-Ruey Chen, Sheng-Wei Lin, Che Ma, Tsui-Ling Hsu and Chi-Huey Wong

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ACS Chemical Biology
DOI: 10.1021/cb500121c
  • Posted in ACS Chemical Biology, Publications
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