Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

June 13th, 2014 by David Albesa-Jové, Laurent R. Chiarelli, Vadim Makarov, Maria Rosalia Pasca, Saioa Urresti, Giorgia Mori, Elena Salina, Anthony Vocat, Natalia Comino, Elisabeth Mohorko, Svetlana Ryabova, Bernhard Pfieiffer, Ana Luisa de Jesus Lopes Ribeiro, Ane Rod

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ACS Chemical Biology
DOI: 10.1021/cb500149m
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Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification

June 11th, 2014 by Lei Fang, K. Martin Chow, Shurong Hou, Liu Xue, Xiabin Chen, David W. Rodgers, Fang Zheng and Chang-Guo Zhan

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ACS Chemical Biology
DOI: 10.1021/cb500257s
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Sequence-Selective Molecular Recognition of the C-Terminal CaaX-Boxes of Rheb and Related Ras-Proteins by Synthetic Receptors

June 11th, 2014 by Peter M. Düppe, Thao Tran Thi Phuong, Jasmin Autzen, Miriam Schöpel, King Tuo Yip, Raphael Stoll and Jürgen Scherkenbeck

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ACS Chemical Biology
DOI: 10.1021/cb5002075
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Chemical Protein Polyubiquitination Reveals the Role of a Noncanonical Polyubiquitin Chain in DNA Damage Tolerance

June 11th, 2014 by Kun Yang, Ping Gong, Parikshit Gokhale and Zhihao Zhuang

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ACS Chemical Biology
DOI: 10.1021/cb500133k
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A Small-Molecule Targeting the MicroRNA Binding Domain of Argonaute 2 improves the Retinoic Acid Differentiation Response of the Acute Promyelocytic Leukemia Cell Line NB4

June 11th, 2014 by Silvia Masciarelli, Roberto Quaranta, Ilaria Iosue, Gianni Colotti, Fabrizio Padula, Greta Varchi, Francesco Fazi and Alberto Del Rio

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ACS Chemical Biology
DOI: 10.1021/cb500286b
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Fluorescent RNA Labeling Using Self-Alkylating Ribozymes

June 11th, 2014 by Ashwani K. Sharma, Joshua J. Plant, Alexandra E. Rangel, Kirsten N. Meek, April J. Anamisis, Julie Hollien and Jennifer M. Heemstra

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ACS Chemical Biology
DOI: 10.1021/cb5002119

Identification of a First Enzymatic Activator of a 17β-Hydroxysteroid Dehydrogenase

June 9th, 2014 by Alexandre Trottier, René Maltais and Donald Poirier

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ACS Chemical Biology
DOI: 10.1021/cb500109e

Blurring the Lines between Ribosomal and Nonribosomal Peptide Scaffolds

June 9th, 2014 by Christopher T. Walsh

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ACS Chemical Biology
DOI: 10.1021/cb5003587

Anatomy of β-Strands at Protein–Protein Interfaces

June 9th, 2014 by Andrew M. Watkins and Paramjit S. Arora

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ACS Chemical Biology
DOI: 10.1021/cb500241y

Chemoproteomics Reveals Time-Dependent Binding of Histone Deacetylase Inhibitors to Endogenous Repressor Complexes

June 6th, 2014 by Isabelle Becher, Antje Dittmann, Mikhail M. Savitski, Carsten Hopf, Gerard Drewes and Marcus Bantscheff

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ACS Chemical Biology
DOI: 10.1021/cb500235n
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