Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

June 17th, 2014 by Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D. Patel, John Koren, Pengrong Yan, Erica M. DaGama Gomes, Chenghua Yang, Maulik R. Patel, Liza Shrestha, Stefan O. Ochiana, Cristina Santarossa, Ronnie Maharaj, Alexander Gozman, Marc B. Cox, Hediye Er

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ACS Chemical Biology
DOI: 10.1021/cb500256u
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Plant, Animal, and Fungal Micronutrient Queuosine Is Salvaged by Members of the DUF2419 Protein Family

June 16th, 2014 by Rémi Zallot, Céline Brochier-Armanet, Kirk W. Gaston, Farhad Forouhar, Patrick A. Limbach, John F. Hunt and Valérie de Crécy-Lagard

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ACS Chemical Biology
DOI: 10.1021/cb500278k
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Nucleophilic 1,4-Additions for Natural Product Discovery

June 16th, 2014 by Courtney L. Cox, Jonathan I. Tietz, Karol Sokolowski, Joel O. Melby, James R. Doroghazi and Douglas A. Mitchell

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ACS Chemical Biology
DOI: 10.1021/cb500324n

Mechanistic Insight with HBCH2CoA as a Probe to Polyhydroxybutyrate (PHB) Synthases

June 16th, 2014 by Wei Zhang, Ruben Shrestha, Rachael M. Buckley, Jamie Jewell, Stefan H. Bossmann, JoAnne Stubbe and Ping Li

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ACS Chemical Biology
DOI: 10.1021/cb5002735

Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA

June 16th, 2014 by Kelly J. Phelps, José M. Ibarra-Soza, Kiet Tran, Andrew J. Fisher and Peter A. Beal

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ACS Chemical Biology
DOI: 10.1021/cb500270x
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Rv2466c Mediates the Activation of TP053 To Kill Replicating and Non-replicating Mycobacterium tuberculosis

June 13th, 2014 by David Albesa-Jové, Laurent R. Chiarelli, Vadim Makarov, Maria Rosalia Pasca, Saioa Urresti, Giorgia Mori, Elena Salina, Anthony Vocat, Natalia Comino, Elisabeth Mohorko, Svetlana Ryabova, Bernhard Pfieiffer, Ana Luisa de Jesus Lopes Ribeiro, Ane Rod

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ACS Chemical Biology
DOI: 10.1021/cb500149m
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Rational Design, Preparation, and Characterization of a Therapeutic Enzyme Mutant with Improved Stability and Function for Cocaine Detoxification

June 11th, 2014 by Lei Fang, K. Martin Chow, Shurong Hou, Liu Xue, Xiabin Chen, David W. Rodgers, Fang Zheng and Chang-Guo Zhan

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ACS Chemical Biology
DOI: 10.1021/cb500257s
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Sequence-Selective Molecular Recognition of the C-Terminal CaaX-Boxes of Rheb and Related Ras-Proteins by Synthetic Receptors

June 11th, 2014 by Peter M. Düppe, Thao Tran Thi Phuong, Jasmin Autzen, Miriam Schöpel, King Tuo Yip, Raphael Stoll and Jürgen Scherkenbeck

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ACS Chemical Biology
DOI: 10.1021/cb5002075
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Chemical Protein Polyubiquitination Reveals the Role of a Noncanonical Polyubiquitin Chain in DNA Damage Tolerance

June 11th, 2014 by Kun Yang, Ping Gong, Parikshit Gokhale and Zhihao Zhuang

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ACS Chemical Biology
DOI: 10.1021/cb500133k
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A Small-Molecule Targeting the MicroRNA Binding Domain of Argonaute 2 improves the Retinoic Acid Differentiation Response of the Acute Promyelocytic Leukemia Cell Line NB4

June 11th, 2014 by Silvia Masciarelli, Roberto Quaranta, Ilaria Iosue, Gianni Colotti, Fabrizio Padula, Greta Varchi, Francesco Fazi and Alberto Del Rio

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ACS Chemical Biology
DOI: 10.1021/cb500286b
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