Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli

July 10th, 2014 by Cecilia Artola-Recolons, Mijoon Lee, Noelia Bernardo-García, Blas Blázquez, Dusan Hesek, Sergio G. Bartual, Kiran V. Mahasenan, Elena Lastochkin, Hualiang Pi, Bill Boggess, Kathrin Meindl, Isabel Usón, Jed F. Fisher, Shahriar Mobashery and Juan A.

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ACS Chemical Biology
DOI: 10.1021/cb500439c

Mia40 Is Optimized for Function in Mitochondrial Oxidative Protein Folding and Import

July 10th, 2014 by Johanna R. Koch and Franz X. Schmid

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ACS Chemical Biology
DOI: 10.1021/cb500408n

Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of Mycobacteria

July 9th, 2014 by Christopher R. Vickery, Nicolas M. Kosa, Ellen P. Casavant, Shiteng Duan, Joseph P. Noel and Michael D. Burkart

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ACS Chemical Biology
DOI: 10.1021/cb500263p
  • Posted in ACS Chemical Biology, Publications
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Alterations in Energy/Redox Metabolism Induced by Mitochondrial and Environmental Toxins: A Specific Role for Glucose-6-Phosphate-Dehydrogenase and the Pentose Phosphate Pathway in Paraquat Toxicity

July 7th, 2014 by Shulei Lei, Laura Zavala-Flores, Aracely Garcia-Garcia, Renu Nandakumar, Yuting Huang, Nandakumar Madayiputhiya, Robert C. Stanton, Eric D. Dodds, Robert Powers and Rodrigo Franco

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ACS Chemical Biology
DOI: 10.1021/cb400894a
  • Posted in ACS Chemical Biology, Publications
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Functional and Structural Characterization of 2-Amino-4-phenylthiazole Inhibitors of the HIV-1 Nucleocapsid Protein with Antiviral Activity

July 7th, 2014 by Mattia Mori, Alessandro Nucci, Maria Chiara Dasso Lang, Nicolas Humbert, Christian Boudier, Francois Debaene, Sarah Sanglier-Cianferani, Marjorie Catala, Patricia Schult-Dietrich, Ursula Dietrich, Carine Tisné, Yves Mely and Maurizio Botta

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ACS Chemical Biology
DOI: 10.1021/cb500316h
  • Posted in ACS Chemical Biology, Publications
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Discovery of Inter-Domain StabilizersA Novel Assay System for Allosteric Akt Inhibitors

July 3rd, 2014 by Zhizhou Fang, Jeffrey R. Simard, Dennis Plenker, Hoang D. Nguyen, Trang Phan, Patrik Wolle, Stefan Baumeister and Daniel Rauh

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ACS Chemical Biology
DOI: 10.1021/cb500355c

Manipulating Unconventional CH-Based Hydrogen Bonding in a Methyltransferase via Noncanonical Amino Acid Mutagenesis

July 3rd, 2014 by Scott Horowitz, Upendra Adhikari, Lynnette M. A. Dirk, Paul A. Del Rizzo, Ryan A. Mehl, Robert L. Houtz, Hashim M. Al-Hashimi, Steve Scheiner and Raymond C. Trievel

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ACS Chemical Biology
DOI: 10.1021/cb5001185
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Structures of Kibdelomycin Bound to Staphylococcus aureus GyrB and ParE Showed a Novel U-Shaped Binding Mode

July 2nd, 2014 by Jun Lu, Sangita Patel, Nandini Sharma, Stephen M. Soisson, Ryuta Kishii, Masaya Takei, Yasumichi Fukuda, Kevin J. Lumb and Sheo B. Singh

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ACS Chemical Biology
DOI: 10.1021/cb5001197
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Divergent Modulation of Src-Family Kinase Regulatory Interactions with ATP-Competitive Inhibitors

July 2nd, 2014 by Stephen E. Leonard, A. C. Register, Ratika Krishnamurty, Gabriel J. Brighty and Dustin J. Maly

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ACS Chemical Biology
DOI: 10.1021/cb500371g
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Relative Positioning of Classical Benzodiazepines to the γ2-Subunit of GABAA Receptors

June 30th, 2014 by Simon J. Middendorp, Evelyn Hurni, Matthias Schönberger, Marco Stein, Michael Pangerl, Dirk Trauner and Erwin Sigel

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ACS Chemical Biology
DOI: 10.1021/cb500186a