Recent Advances in Radical SAM Enzymology: New Structures and Mechanisms

July 15th, 2014 by Jiarui Wang, Rory P. Woldring, Gabriel D. Román-Meléndez, Alan M. McClain, Brian R. Alzua and E. Neil G. Marsh

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ACS Chemical Biology
DOI: 10.1021/cb5004674

Genetically Encoding an Electrophilic Amino Acid for Protein Stapling and Covalent Binding to Native Receptors

July 15th, 2014 by Xiao-Hua Chen, Zheng Xiang, Ying S. Hu, Vanessa K. Lacey, Hu Cang and Lei Wang

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ACS Chemical Biology
DOI: 10.1021/cb500453a
  • Posted in ACS Chemical Biology, Publications
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Molecular Basis for Small Molecule Inhibition of G Protein-Coupled Receptor Kinases

July 14th, 2014 by Kristoff T. Homan and John J. G. Tesmer

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ACS Chemical Biology
DOI: 10.1021/cb5003976

Toxicity Modulation, Resistance Enzyme Evasion, and A-Site X-ray Structure of Broad-Spectrum Antibacterial Neomycin Analogs

July 14th, 2014 by Juan Pablo Maianti, Hiroki Kanazawa, Paola Dozzo, Rowena D. Matias, Lee Ann Feeney, Eliana S. Armstrong, Darin J. Hildebrandt, Timothy R. Kane, Micah J. Gliedt, Adam A. Goldblum, Martin S. Linsell, James B. Aggen, Jiro Kondo and Stephen Hanessian

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ACS Chemical Biology
DOI: 10.1021/cb5003416
  • Posted in ACS Chemical Biology, Publications
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Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli

July 10th, 2014 by Cecilia Artola-Recolons, Mijoon Lee, Noelia Bernardo-García, Blas Blázquez, Dusan Hesek, Sergio G. Bartual, Kiran V. Mahasenan, Elena Lastochkin, Hualiang Pi, Bill Boggess, Kathrin Meindl, Isabel Usón, Jed F. Fisher, Shahriar Mobashery and Juan A.

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ACS Chemical Biology
DOI: 10.1021/cb500439c

Mia40 Is Optimized for Function in Mitochondrial Oxidative Protein Folding and Import

July 10th, 2014 by Johanna R. Koch and Franz X. Schmid

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ACS Chemical Biology
DOI: 10.1021/cb500408n

Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of Mycobacteria

July 9th, 2014 by Christopher R. Vickery, Nicolas M. Kosa, Ellen P. Casavant, Shiteng Duan, Joseph P. Noel and Michael D. Burkart

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ACS Chemical Biology
DOI: 10.1021/cb500263p
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Alterations in Energy/Redox Metabolism Induced by Mitochondrial and Environmental Toxins: A Specific Role for Glucose-6-Phosphate-Dehydrogenase and the Pentose Phosphate Pathway in Paraquat Toxicity

July 7th, 2014 by Shulei Lei, Laura Zavala-Flores, Aracely Garcia-Garcia, Renu Nandakumar, Yuting Huang, Nandakumar Madayiputhiya, Robert C. Stanton, Eric D. Dodds, Robert Powers and Rodrigo Franco

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ACS Chemical Biology
DOI: 10.1021/cb400894a
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Functional and Structural Characterization of 2-Amino-4-phenylthiazole Inhibitors of the HIV-1 Nucleocapsid Protein with Antiviral Activity

July 7th, 2014 by Mattia Mori, Alessandro Nucci, Maria Chiara Dasso Lang, Nicolas Humbert, Christian Boudier, Francois Debaene, Sarah Sanglier-Cianferani, Marjorie Catala, Patricia Schult-Dietrich, Ursula Dietrich, Carine Tisné, Yves Mely and Maurizio Botta

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ACS Chemical Biology
DOI: 10.1021/cb500316h
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Discovery of Inter-Domain StabilizersA Novel Assay System for Allosteric Akt Inhibitors

July 3rd, 2014 by Zhizhou Fang, Jeffrey R. Simard, Dennis Plenker, Hoang D. Nguyen, Trang Phan, Patrik Wolle, Stefan Baumeister and Daniel Rauh

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ACS Chemical Biology
DOI: 10.1021/cb500355c