Probing Chromatin-modifying Enzymes with Chemical Tools

February 4th, 2016 by Wolfgang Fischle and Dirk Schwarzer

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b01023

Protein Arginine Methylation and Citrullination in Epigenetic Regulation

December 31st, 2015 by Jakob Fuhrmann and Paul R. Thompson

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00942

Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage

December 29th, 2015 by Na An, Aaron M. Fleming and Cynthia J. Burrows

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00844
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Boronic Acid for the Traceless Delivery of Proteins into Cells

December 15th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00966

Mitochondria-Targeted Approach: Remarkably Enhanced Cellular Bioactivities of TPP2a as Selective Inhibitor and Probe toward TrxR

December 14th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00708
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Three Residues Make an Evolutionary Switch for Folding and RNA-Destabilizing Activity in the TTP Family of Proteins

December 14th, 2015 by Laura M. Deveau and Francesca Massi

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00639
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Azacyclic FTY720 Analogues That Limit Nutrient Transporter Expression but Lack S1P Receptor Activity and Negative Chronotropic Effects Offer a Novel and Effective Strategy to Kill Cancer Cells in Vivo

December 14th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00761
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Thiostrepton Variants Containing a Contracted Quinaldic Acid Macrocycle Result from Mutagenesis of the Second Residue

December 14th, 2015 by Feifei Zhang, Chaoxuan Li and Wendy L. Kelly

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00731
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NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

December 10th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00753
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Barrel-shaped ClpP Proteases Display Attenuated Cleavage Specificities

December 9th, 2015 by

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00757