Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases

August 18th, 2014 by Jeremy C. Henderson, Christopher D. Fage, Joe R. Cannon, Jennifer S. Brodbelt, Adrian T. Keatinge-Clay and M. Stephen Trent

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ACS Chemical Biology
DOI: 10.1021/cb500438x
  • Posted in ACS Chemical Biology, Publications
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Platinum-RNA Modifications Following Drug Treatment in S. cerevisiae Identified by Click Chemistry and Enzymatic Mapping

August 15th, 2014 by Maire F. Osborn, Jonathan D. White, Michael M. Haley and Victoria J. DeRose

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ACS Chemical Biology
DOI: 10.1021/cb500395z
  • Posted in ACS Chemical Biology, Publications
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Ebselen Inhibits Hepatitis C Virus NS3 Helicase Binding to Nucleic Acid and Prevents Viral Replication

August 15th, 2014 by Sourav Mukherjee, Warren S. Weiner, Chad E. Schroeder, Denise S. Simpson, Alicia M. Hanson, Noreena L. Sweeney, Rachel K. Marvin, Jean Ndjomou, Rajesh Kolli, Dragan Isailovic, Frank J. Schoenen and David N. Frick

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ACS Chemical Biology
DOI: 10.1021/cb500512z
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A Double-Hotdog with a New Trick: Structure and Mechanism of the trans-Acyltransferase Polyketide Synthase Enoyl-isomerase

August 14th, 2014 by Darren C. Gay, Philip J. Spear and Adrian T. Keatinge-Clay

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ACS Chemical Biology
DOI: 10.1021/cb500459b
  • Posted in ACS Chemical Biology, Publications
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Potent Antimalarial Activity of Acriflavine In Vitro and In Vivo

August 14th, 2014 by Srikanta Dana, Dhaneswar Prusty, Devender Dhayal, Mohit Kumar Gupta, Ashraf Dar, Sobhan Sen, Pritam Mukhopadhyay, Tridibesh Adak and Suman Kumar Dhar

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ACS Chemical Biology
DOI: 10.1021/cb500476q

A Rapid SNAP-Tag Fluorogenic Probe Based on an Environment-Sensitive Fluorophore for No-Wash Live Cell Imaging

August 13th, 2014 by Tao-Kai Liu, Pei-Ying Hsieh, Yu-De Zhuang, Chi-Yang Hsia, Chi-Ling Huang, Hsiu-Ping Lai, Hung-Sheung Lin, I-Chia Chen, Hsin-Yun Hsu and Kui-Thong Tan

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ACS Chemical Biology
DOI: 10.1021/cb500502n
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Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19

August 13th, 2014 by Sherif I. Elshahawi, Theresa A. Ramelot, Jayaraman Seetharaman, Jing Chen, Shanteri Singh, Yunhuang Yang, Kari Pederson, Madan K. Kharel, Rong Xiao, Scott Lew, Ragothaman M. Yennamalli, Mitchell D. Miller, Fengbin Wang, Liang Tong, Gaetano T. Monteli

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ACS Chemical Biology
DOI: 10.1021/cb500327m
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Redesigning Human 2′-Deoxycytidine Kinase Enantioselectivity for l-Nucleoside Analogues as Reporters in Positron Emission Tomography

August 12th, 2014 by Pravin Muthu, Hannah X. Chen and Stefan Lutz

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ACS Chemical Biology
DOI: 10.1021/cb500463f
  • Posted in ACS Chemical Biology, Publications
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Toxicity of Protein Oligomers Is Rationalized by a Function Combining Size and Surface Hydrophobicity

August 11th, 2014 by Benedetta Mannini, Estefania Mulvihill, Caterina Sgromo, Roberta Cascella, Reza Khodarahmi, Matteo Ramazzotti, Christopher M. Dobson, Cristina Cecchi and Fabrizio Chiti

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ACS Chemical Biology
DOI: 10.1021/cb500505m
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An Unbiased Approach To Identify Endogenous Substrates of “Histone” Deacetylase 8

August 11th, 2014 by David E. Olson, Namrata D. Udeshi, Noah A. Wolfson, Carol Ann Pitcairn, Eric D. Sullivan, Jacob D. Jaffe, Tanya Svinkina, Ted Natoli, Xiaodong Liu, Joshiawa Paulk, Patrick McCarren, Florence F. Wagner, Doug Barker, Eleanor Howe, Fanny Lazzaro, Jennif

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ACS Chemical Biology
DOI: 10.1021/cb500492r