RNA Mango Aptamer-Fluorophore: A Bright, High-Affinity Complex for RNA Labeling and Tracking

August 21st, 2014 by Elena V. Dolgosheina, Sunny C. Y. Jeng, Shanker Shyam S. Panchapakesan, Razvan Cojocaru, Patrick S. K. Chen, Peter D. Wilson, Nancy Hawkins, Paul A. Wiggins and Peter J. Unrau

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ACS Chemical Biology
DOI: 10.1021/cb500499x

Resurfaced Shape Complementary Proteins That Selectively Bind the Oncoprotein Gankyrin

August 21st, 2014 by Alex M. Chapman and Brian R. McNaughton

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ACS Chemical Biology
DOI: 10.1021/cb5003834

Discovery of a Highly Selective Caspase-3 Substrate for Imaging Live Cells

August 20th, 2014 by Chris J. Vickers, Gonzalo E. González-Páez and Dennis W. Wolan

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ACS Chemical Biology
DOI: 10.1021/cb500586p

Competition Studies Confirm Two Major Barriers That Can Preclude the Spread of Resistance to Quorum-Sensing Inhibitors in Bacteria

August 19th, 2014 by Joseph P. Gerdt and Helen E. Blackwell

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ACS Chemical Biology
DOI: 10.1021/cb5004288
  • Posted in ACS Chemical Biology, Publications
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Asymmetrical Distribution of Choline Phospholipids Revealed by Click Chemistry and Freeze-Fracture Electron Microscopy

August 19th, 2014 by Shohei Iyoshi, Jinglei Cheng, Tsuyako Tatematsu, Sho Takatori, Masayasu Taki, Yukio Yamamoto, Adrian Salic and Toyoshi Fujimoto

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ACS Chemical Biology
DOI: 10.1021/cb500558n
  • Posted in ACS Chemical Biology, Publications
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Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases

August 18th, 2014 by Jeremy C. Henderson, Christopher D. Fage, Joe R. Cannon, Jennifer S. Brodbelt, Adrian T. Keatinge-Clay and M. Stephen Trent

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ACS Chemical Biology
DOI: 10.1021/cb500438x
  • Posted in ACS Chemical Biology, Publications
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Platinum-RNA Modifications Following Drug Treatment in S. cerevisiae Identified by Click Chemistry and Enzymatic Mapping

August 15th, 2014 by Maire F. Osborn, Jonathan D. White, Michael M. Haley and Victoria J. DeRose

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ACS Chemical Biology
DOI: 10.1021/cb500395z
  • Posted in ACS Chemical Biology, Publications
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Ebselen Inhibits Hepatitis C Virus NS3 Helicase Binding to Nucleic Acid and Prevents Viral Replication

August 15th, 2014 by Sourav Mukherjee, Warren S. Weiner, Chad E. Schroeder, Denise S. Simpson, Alicia M. Hanson, Noreena L. Sweeney, Rachel K. Marvin, Jean Ndjomou, Rajesh Kolli, Dragan Isailovic, Frank J. Schoenen and David N. Frick

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ACS Chemical Biology
DOI: 10.1021/cb500512z
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A Double-Hotdog with a New Trick: Structure and Mechanism of the trans-Acyltransferase Polyketide Synthase Enoyl-isomerase

August 14th, 2014 by Darren C. Gay, Philip J. Spear and Adrian T. Keatinge-Clay

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ACS Chemical Biology
DOI: 10.1021/cb500459b
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Potent Antimalarial Activity of Acriflavine In Vitro and In Vivo

August 14th, 2014 by Srikanta Dana, Dhaneswar Prusty, Devender Dhayal, Mohit Kumar Gupta, Ashraf Dar, Sobhan Sen, Pritam Mukhopadhyay, Tridibesh Adak and Suman Kumar Dhar

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ACS Chemical Biology
DOI: 10.1021/cb500476q