Novel Imidazoline Antimicrobial Scaffold That Inhibits DNA Replication with Activity against Mycobacteria and Drug Resistant Gram-Positive Cocci

September 15th, 2014 by Kendra K. Harris, Allison Fay, Han-Guang Yan, Pratima Kunwar, Nicholas D. Socci, Narender Pottabathini, Ramakrishna R. Juventhala, Hakim Djaballah and Michael S. Glickman

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ACS Chemical Biology
DOI: 10.1021/cb500573z
  • Posted in ACS Chemical Biology, Publications
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Insights into Substrate and Metal Binding from the Crystal Structure of Cyanobacterial Aldehyde Deformylating Oxygenase with Substrate Bound

September 15th, 2014 by Benjamin C. Buer, Bishwajit Paul, Debasis Das, Jeanne A. Stuckey and E. Neil G. Marsh

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ACS Chemical Biology
DOI: 10.1021/cb500343j
  • Posted in ACS Chemical Biology, Publications
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An Aptamer to the MAP Kinase Insert Region

September 10th, 2014 by Sabine Lennarz, Elena Heider, Michael Blind and Günter Mayer

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ACS Chemical Biology
DOI: 10.1021/cb5005756

Aldehyde Recognition and Discrimination by Mammalian Odorant Receptors via Functional Group-Specific Hydration Chemistry

September 10th, 2014 by Yadi Li, Zita Peterlin, Jianghai Ho, Tali Yarnitzky, Min Ting Liu, Merav Fichman, Masha Y. Niv, Hiroaki Matsunami, Stuart Firestein and Kevin Ryan

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ACS Chemical Biology
DOI: 10.1021/cb400290u
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pHLIP-FIRE, a Cell Insertion-Triggered Fluorescent Probe for Imaging Tumors Demonstrates Targeted Cargo Delivery In Vivo

September 10th, 2014 by Alexander G. Karabadzhak, Ming An, Lan Yao, Rachel Langenbacher, Anna Moshnikova, Ramona-Cosmina Adochite, Oleg A. Andreev, Yana K. Reshetnyak and Donald M. Engelman

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ACS Chemical Biology
DOI: 10.1021/cb500388m
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Modulation of Gephyrin-Glycine Receptor Affinity by Multivalency

September 10th, 2014 by Hans Michael Maric, Vikram Babu Kasaragod and Hermann Schindelin

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ACS Chemical Biology
DOI: 10.1021/cb500303a

General Platform for Systematic Quantitative Evaluation of Small-Molecule Permeability in Bacteria

September 8th, 2014 by Tony D. Davis, Christopher J. Gerry and Derek S. Tan

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ACS Chemical Biology
DOI: 10.1021/cb5003015
  • Posted in ACS Chemical Biology, Publications
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Small-Molecule Inhibitors of SETD8 with Cellular Activity

September 3rd, 2014 by Gil Blum, Glorymar Ibáñez, Xiangjun Rao, David Shum, Constantin Radu, Hakim Djaballah, Judd C. Rice and Minkui Luo

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ACS Chemical Biology
DOI: 10.1021/cb500515r

Characterization of Two Distinct Modes of Drug Binding to Human Intestinal Fatty Acid Binding Protein

September 2nd, 2014 by Rahul Patil, Aisha Laguerre, Jerome Wielens, Stephen J. Headey, Martin L. Williams, Maria L. R. Hughes, Biswaranjan Mohanty, Christopher J. H. Porter and Martin J. Scanlon

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ACS Chemical Biology
DOI: 10.1021/cb5005178
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Loop Electrostatics Modulates the Intersubunit Interactions in Ferritin

August 29th, 2014 by Caterina Bernacchioni, Veronica Ghini, Cecilia Pozzi, Flavio Di Pisa, Elizabeth C. Theil and Paola Turano

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ACS Chemical Biology
DOI: 10.1021/cb500431r