4-Methylproline Guided Natural Product Discovery: Co-Occurrence of 4-Hydroxy- and 4-Methylprolines in Nostoweipeptins and Nostopeptolides

September 25th, 2014 by Liwei Liu, Jouni Jokela, Lars Herfindal, Matti Wahlsten, Jari Sinkkonen, Perttu Permi, David P Fewer, Stein Ove Døskeland and Kaarina Sivonen

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ACS Chemical Biology
DOI: 10.1021/cb500436p
  • Posted in ACS Chemical Biology, Publications
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The Renaissance of Ras

September 23rd, 2014 by Lech-Gustav Milroy and Christian Ottmann

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ACS Chemical Biology
DOI: 10.1021/cb500555h

Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome

September 22nd, 2014 by Arren Z. Washington, Derek B. Benicewicz, Joshua C. Canzoneri, Crystal E. Fagan, Sandra C. Mwakwari, Tatsuya Maehigashi, Christine M. Dunham and Adegboyega K. Oyelere

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ACS Chemical Biology
DOI: 10.1021/cb5003224
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A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis

September 22nd, 2014 by Meng Yang, Kip E. Guja, Suzanne T. Thomas, Miguel Garcia-Diaz and Nicole S. Sampson

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ACS Chemical Biology
DOI: 10.1021/cb500232h
  • Posted in ACS Chemical Biology, Publications
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Toward Peptide Nucleic Acid (PNA) Directed Peptide Translation Using Ester Based Aminoacyl Transfer

September 18th, 2014 by Abhishek Singhal, Valentina Bagnacani, Roberto Corradini and Peter E. Nielsen

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ACS Chemical Biology
DOI: 10.1021/cb5005349
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Rapid Transfer of Transmembrane Proteins for Single Molecule Dimerization Assays in Polymer-Supported Membranes

September 16th, 2014 by Friedrich Roder, Stephan Wilmes, Christian P. Richter and Jacob Piehler

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ACS Chemical Biology
DOI: 10.1021/cb5005806
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Identification of Small Molecule Modulators of Gene Transcription with Anticancer Activity

September 16th, 2014 by Tram Anh Tran, Jennifer Wichterman-Kouznetsova, Diana Varghese, Ruili Huang, Wenwei Huang, Matthias Becker, Christopher P. Austin, James Inglese, Ronald L. Johnson and Elisabeth D. Martinez

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ACS Chemical Biology
DOI: 10.1021/cb500532x

Genome Editing-Enabled HTS Assays Expand Drug Target Pathways for Charcot–Marie–Tooth Disease

September 16th, 2014 by James Inglese, Patricia Dranchak, John J. Moran, Sung-Wook Jang, Rajini Srinivasan, Yolanda Santiago, Lei Zhang, Rajarshi Guha, Natalia Martinez, Ryan MacArthur, Gregory J. Cost and John Svaren

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ACS Chemical Biology
DOI: 10.1021/cb5005492
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Novel Imidazoline Antimicrobial Scaffold That Inhibits DNA Replication with Activity against Mycobacteria and Drug Resistant Gram-Positive Cocci

September 15th, 2014 by Kendra K. Harris, Allison Fay, Han-Guang Yan, Pratima Kunwar, Nicholas D. Socci, Narender Pottabathini, Ramakrishna R. Juventhala, Hakim Djaballah and Michael S. Glickman

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ACS Chemical Biology
DOI: 10.1021/cb500573z
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Insights into Substrate and Metal Binding from the Crystal Structure of Cyanobacterial Aldehyde Deformylating Oxygenase with Substrate Bound

September 15th, 2014 by Benjamin C. Buer, Bishwajit Paul, Debasis Das, Jeanne A. Stuckey and E. Neil G. Marsh

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ACS Chemical Biology
DOI: 10.1021/cb500343j
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