Recent Progress in Design of Protein-Based Fluorescent Biosensors and Their Cellular Applications

October 23rd, 2014 by Tomonori Tamura and Itaru Hamachi

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500661v
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Recent Progress in Design of Protein-Based Fluorescent Biosensors and Their Cellular Applications

Clickable Analogue of Cerulenin as Chemical Probe to Explore Protein Palmitoylation

October 23rd, 2014 by Baohui Zheng, Shunying Zhu and Xu Wu

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500758s

Lipid-Dependent Bimodal MCL1 Membrane Activity

October 22nd, 2014 by Olatz Landeta, Juan GarciaValero, Hector Flores-Romero, Itsasne Bustillo-Zabalbeitia, Ane Landajuela, Miguel Garcia-Porras, Oihana Terrones and Gorka Basañez

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500592e

MitoBlue: A Nontoxic and Photostable Blue-Emitting Dye That Selectively Labels Functional Mitochondria

October 21st, 2014 by Mateo I. Sánchez, José Martínez-Costas, José L. Mascareñas and M. Eugenio Vázquez

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500552f
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on MitoBlue: A Nontoxic and Photostable Blue-Emitting Dye That Selectively Labels Functional Mitochondria

Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis

October 21st, 2014 by Brahm J. Yachnin, Michelle B. McEvoy, Roderick J. D. MacCuish, Krista L. Morley, Peter C. K. Lau and Albert M. Berghuis

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500442e
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Lactone-Bound Structures of Cyclohexanone Monooxygenase Provide Insight into the Stereochemistry of Catalysis

Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates

October 20th, 2014 by Whitney C. Duim, Yan Jiang, Koning Shen, Judith Frydman and W. E. Moerner

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500335w
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates

Exploring a 2-Naphthoic Acid Template for the Structure-Based Design of P2Y14 Receptor Antagonist Molecular Probes

October 20th, 2014 by Evgeny Kiselev, Matthew O. Barrett, Vsevolod Katritch, Silvia Paoletta, Clarissa D. Weitzer, Kyle A. Brown, Eva Hammes, Andrew L. Yin, Qiang Zhao, Raymond C. Stevens, T. Kendall Harden and Kenneth A. Jacobson

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500614p
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Exploring a 2-Naphthoic Acid Template for the Structure-Based Design of P2Y14 Receptor Antagonist Molecular Probes

Chemoproteomics Demonstrates Target Engagement and Exquisite Selectivity of the Clinical Phosphodiesterase 10A Inhibitor MP-10 in Its Native Environment

October 19th, 2014 by Jan-Philip Schülke, Laura A. McAllister, Kieran F. Geoghegan, Vinod Parikh, Thomas A. Chappie, Patrick R. Verhoest, Christopher J. Schmidt, Douglas S. Johnson and Nicholas J. Brandon

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500671j
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Chemoproteomics Demonstrates Target Engagement and Exquisite Selectivity of the Clinical Phosphodiesterase 10A Inhibitor MP-10 in Its Native Environment

Evolved Sequence Contexts for Highly Efficient Amber Suppression with Noncanonical Amino Acids

October 16th, 2014 by Moritz Pott, Moritz Johannes Schmidt and Daniel Summerer

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb5006273

Identification of Small Molecules That Protect Pancreatic β Cells against Endoplasmic Reticulum Stress-Induced Cell Death

October 16th, 2014 by Kim Tran, Yu Li, Hongliang Duan, Daleep Arora, Hui-Ying Lim and Weidong Wang

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500740d
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Identification of Small Molecules That Protect Pancreatic β Cells against Endoplasmic Reticulum Stress-Induced Cell Death