Mutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials

November 5th, 2014 by Erika L. Flannery, Case W. McNamara, Sang Wan Kim, Tomoyo Sakata Kato, Fengwu Li, Christine H. Teng, Kerstin Gagaring, Micah J. Manary, Rachel Barboa, Stephan Meister, Kelli Kuhen, Joseph M. Vinetz, Arnab K. Chatterjee and Elizabeth A. Winzeler

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ACS Chemical Biology
DOI: 10.1021/cb500616x
  • Posted in ACS Chemical Biology, Publications
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A Genetically Encoded Alkyne Directs Palladium-Mediated Protein Labeling on Live Mammalian Cell Surface

November 5th, 2014 by Nan Li, Carlo P. Ramil, Reyna K. V. Lim and Qing Lin

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ACS Chemical Biology
DOI: 10.1021/cb500649q
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Bypassing Fluoroquinolone Resistance with Quinazolinediones: Studies of Drug–Gyrase–DNA Complexes Having Implications for Drug Design

November 4th, 2014 by Karl Drlica, Arkady Mustaev, Tyrell R. Towle, Gan Luan, Robert J. Kerns and James M. Berger

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ACS Chemical Biology
DOI: 10.1021/cb500629k
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Identification of a Small Molecule That Turns ON the Pluripotency Gene Circuitry in Human Fibroblasts

November 4th, 2014 by Ganesh N. Pandian, Shinsuke Sato, Chandran Anandhakumar, Junichi Taniguchi, Kazuhiro Takashima, Junetha Syed, Le Han, Abhijit Saha, Toshikazu Bando, Hiroki Nagase and Hiroshi Sugiyama

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ACS Chemical Biology
DOI: 10.1021/cb500724t
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Tuning the Affinity of Anion Binding Sites in Porin Channels with Negatively Charged Residues: Molecular Details for OprP

October 31st, 2014 by Niraj Modi, Iván Bárcena-Uribarri, Manjeet Bains, Roland Benz, Robert E. W. Hancock and Ulrich Kleinekathöfer

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ACS Chemical Biology
DOI: 10.1021/cb500399j
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Recoding Aminoacyl-tRNA Synthetases for Synthetic Biology by Rational Protein-RNA Engineering

October 31st, 2014 by Andrew Hadd and John J. Perona

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ACS Chemical Biology
DOI: 10.1021/cb5006596

Development of Substrate-Selective Probes for Affinity Pulldown of Histone Demethylases

October 29th, 2014 by Laura J. Marholz, Le Chang, William M. Old and Xiang Wang

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ACS Chemical Biology
DOI: 10.1021/cb5006867

Biological Matching of Chemical Reactivity: Pairing Indole Nucleophilicity with Electrophilic Isoprenoids

October 29th, 2014 by Christopher T. Walsh

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ACS Chemical Biology
DOI: 10.1021/cb500695k
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Phosphatase-Inert Glucosamine 6-Phosphate Mimics Serve as Actuators of the glmS Riboswitch

October 27th, 2014 by Xiang Fei, Thomas Holmes, Julianna Diddle, Lauren Hintz, Dan Delaney, Alex Stock, Danielle Renner, Molly McDevitt, David B. Berkowitz and Juliane K. Soukup

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ACS Chemical Biology
DOI: 10.1021/cb500458f

DFG-out Mode of Inhibition by an Irreversible Type-1 Inhibitor Capable of Overcoming Gate-Keeper Mutations in FGF Receptors

October 27th, 2014 by Zhifeng Huang, Li Tan, Huiyan Wang, Yang Liu, Steven Blais, Jingjing Deng, Thomas A. Neubert, Nathanael S. Gray, Xiaokun Li and Moosa Mohammadi

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ACS Chemical Biology
DOI: 10.1021/cb500674s
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