Regulation of Wnt Signaling Target Gene Expression by the Histone Methyltransferase DOT1L

November 10th, 2014 by Garrett S. Gibbons, Scott R. Owens, Eric R. Fearon and Zaneta Nikolovska-Coleska

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ACS Chemical Biology
DOI: 10.1021/cb500668u

Peptide-Based, Two-Fluorophore, Ratiometric Probe for Quantifying Mobile Zinc in Biological Solutions

November 10th, 2014 by Daniel Y. Zhang, Maria Azrad, Wendy Demark-Wahnefried, Christopher J. Frederickson, Stephen J. Lippard and Robert J. Radford

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ACS Chemical Biology
DOI: 10.1021/cb500617c
  • Posted in ACS Chemical Biology, Publications
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One-Step Enzymatic Modification of the Cell Surface Redirects Cellular Cytotoxicity and Parasite Tropism

November 10th, 2014 by Lee Kim Swee, Sebastian Lourido, George W. Bell, Jessica R. Ingram and Hidde L. Ploegh

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ACS Chemical Biology
DOI: 10.1021/cb500462t
  • Posted in ACS Chemical Biology, Publications
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Multicolor Monitoring of the Proteasome’s Catalytic Signature

November 7th, 2014 by Melanie A. Priestman, Qunzhao Wang, Finith E. Jernigan, Ruma Chowdhury, Marion Schmidt and David S. Lawrence

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ACS Chemical Biology
DOI: 10.1021/cb5007322

Changing the Selectivity of p300 by Acetyl-CoA Modulation of Histone Acetylation

November 6th, 2014 by Ryan A. Henry, Yin-Ming Kuo, Vikram Bhattacharjee, Timothy J. Yen and Andrew J. Andrews

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ACS Chemical Biology
DOI: 10.1021/cb500726b

Distant Polypharmacology among MLP Chemical Probes

November 6th, 2014 by Albert A. Antolín and Jordi Mestres

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ACS Chemical Biology
DOI: 10.1021/cb500393m

Unified and Isomer-Specific NMR Metabolomics Database for the Accurate Analysis of 13C–1H HSQC Spectra

November 5th, 2014 by Kerem Bingol, Da-Wei Li, Lei Bruschweiler-Li, Oscar A. Cabrera, Timothy Megraw, Fengli Zhang and Rafael Brüschweiler

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ACS Chemical Biology
DOI: 10.1021/cb5006382
  • Posted in ACS Chemical Biology, Publications
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Chemical Genetics Screening Reveals KIAA1363 as a Cytokine-Lowering Target

November 5th, 2014 by Devon M. Hunerdosse, Patrick J. Morris, David K. Miyamoto, Karl J. Fisher, Leslie A. Bateman, Jonathan R. Ghazaleh, Sharon Zhong and Daniel K. Nomura

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ACS Chemical Biology
DOI: 10.1021/cb500717g

Polyketide Intermediate Mimics as Probes for Revealing Cryptic Stereochemistry of Ketoreductase Domains

November 5th, 2014 by Yang Li, William D. Fiers, Steffen M. Bernard, Janet L. Smith, Courtney C. Aldrich and Robert A. Fecik

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ACS Chemical Biology
DOI: 10.1021/cb5006883
  • Posted in ACS Chemical Biology, Publications
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Analysis of Phosphorylation-Dependent Protein–Protein Interactions of Histone H3

November 5th, 2014 by Rebecca Klingberg, Jan Oliver Jost, Michael Schümann, Kathy Ann Gelato, Wolfgang Fischle, Eberhard Krause and Dirk Schwarzer

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ACS Chemical Biology
DOI: 10.1021/cb500563n