Changing the Selectivity of p300 by Acetyl-CoA Modulation of Histone Acetylation

November 6th, 2014 by Ryan A. Henry, Yin-Ming Kuo, Vikram Bhattacharjee, Timothy J. Yen and Andrew J. Andrews

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ACS Chemical Biology
DOI: 10.1021/cb500726b

Distant Polypharmacology among MLP Chemical Probes

November 6th, 2014 by Albert A. Antolín and Jordi Mestres

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ACS Chemical Biology
DOI: 10.1021/cb500393m

Unified and Isomer-Specific NMR Metabolomics Database for the Accurate Analysis of 13C–1H HSQC Spectra

November 5th, 2014 by Kerem Bingol, Da-Wei Li, Lei Bruschweiler-Li, Oscar A. Cabrera, Timothy Megraw, Fengli Zhang and Rafael Brüschweiler

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ACS Chemical Biology
DOI: 10.1021/cb5006382
  • Posted in ACS Chemical Biology, Publications
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Chemical Genetics Screening Reveals KIAA1363 as a Cytokine-Lowering Target

November 5th, 2014 by Devon M. Hunerdosse, Patrick J. Morris, David K. Miyamoto, Karl J. Fisher, Leslie A. Bateman, Jonathan R. Ghazaleh, Sharon Zhong and Daniel K. Nomura

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ACS Chemical Biology
DOI: 10.1021/cb500717g

Polyketide Intermediate Mimics as Probes for Revealing Cryptic Stereochemistry of Ketoreductase Domains

November 5th, 2014 by Yang Li, William D. Fiers, Steffen M. Bernard, Janet L. Smith, Courtney C. Aldrich and Robert A. Fecik

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ACS Chemical Biology
DOI: 10.1021/cb5006883
  • Posted in ACS Chemical Biology, Publications
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Analysis of Phosphorylation-Dependent Protein–Protein Interactions of Histone H3

November 5th, 2014 by Rebecca Klingberg, Jan Oliver Jost, Michael Schümann, Kathy Ann Gelato, Wolfgang Fischle, Eberhard Krause and Dirk Schwarzer

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ACS Chemical Biology
DOI: 10.1021/cb500563n

Mutations in the P-Type Cation-Transporter ATPase 4, PfATP4, Mediate Resistance to Both Aminopyrazole and Spiroindolone Antimalarials

November 5th, 2014 by Erika L. Flannery, Case W. McNamara, Sang Wan Kim, Tomoyo Sakata Kato, Fengwu Li, Christine H. Teng, Kerstin Gagaring, Micah J. Manary, Rachel Barboa, Stephan Meister, Kelli Kuhen, Joseph M. Vinetz, Arnab K. Chatterjee and Elizabeth A. Winzeler

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ACS Chemical Biology
DOI: 10.1021/cb500616x
  • Posted in ACS Chemical Biology, Publications
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A Genetically Encoded Alkyne Directs Palladium-Mediated Protein Labeling on Live Mammalian Cell Surface

November 5th, 2014 by Nan Li, Carlo P. Ramil, Reyna K. V. Lim and Qing Lin

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ACS Chemical Biology
DOI: 10.1021/cb500649q
  • Posted in ACS Chemical Biology, Publications
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Bypassing Fluoroquinolone Resistance with Quinazolinediones: Studies of Drug–Gyrase–DNA Complexes Having Implications for Drug Design

November 4th, 2014 by Karl Drlica, Arkady Mustaev, Tyrell R. Towle, Gan Luan, Robert J. Kerns and James M. Berger

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ACS Chemical Biology
DOI: 10.1021/cb500629k
  • Posted in ACS Chemical Biology, Publications
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Identification of a Small Molecule That Turns ON the Pluripotency Gene Circuitry in Human Fibroblasts

November 4th, 2014 by Ganesh N. Pandian, Shinsuke Sato, Chandran Anandhakumar, Junichi Taniguchi, Kazuhiro Takashima, Junetha Syed, Le Han, Abhijit Saha, Toshikazu Bando, Hiroki Nagase and Hiroshi Sugiyama

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ACS Chemical Biology
DOI: 10.1021/cb500724t
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