Interfacing Chemical Biology and Drug Discovery: Report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2–4, 2014, Rouen, France

December 5th, 2014 by Janos Sapi, Frédéric Schmidt, Luc Van Hijfte and Pascal George

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ACS Chemical Biology
DOI: 10.1021/cb5009469
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Identifying Modulators of CXC Receptors 3 and 4 with Tailored Selectivity Using Multi-Target Docking

December 5th, 2014 by Denis Schmidt, Viachaslau Bernat, Regine Brox, Nuska Tschammer and Peter Kolb

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ACS Chemical Biology
DOI: 10.1021/cb500577j
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Probing Interactions between Lysine Residues in Histone Tails and Nucleosomal DNA via Product and Kinetic Analysis

December 5th, 2014 by Liwei Weng, Chuanzheng Zhou and Marc M. Greenberg

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ACS Chemical Biology
DOI: 10.1021/cb500737y
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Pseudoaeruginosins, Nonribosomal Peptides in Nodularia spumigena

December 5th, 2014 by Liwei Liu, Adnan Budnjo, Jouni Jokela, Bengt Erik Haug, David P. Fewer, Matti Wahlsten, Leo Rouhiainen, Perttu Permi, Torgils Fossen and Kaarina Sivonen

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ACS Chemical Biology
DOI: 10.1021/cb5004306

Natural Combinatorial Biosynthesis Involving Two Clusters for the Synthesis of Three Pyrrolamides in Streptomyces netropsis

December 4th, 2014 by Audrey Vingadassalon, Florence Lorieux, Maud Juguet, Géraldine Le Goff, Claude Gerbaud, Jean-Luc Pernodet and Sylvie Lautru

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ACS Chemical Biology
DOI: 10.1021/cb500652n
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Molecular Basis of Selective Inhibition and Slow Reversibility of Avibactam against Class D Carbapenemases: A Structure-Guided Study of OXA-24 and OXA-48

December 4th, 2014 by Sushmita D. Lahiri, Stefano Mangani, Haris Jahić, Manuela Benvenuti, Thomas F. Durand-Reville, Filomena De Luca, David E. Ehmann, Gian Maria Rossolini, Richard A Alm and Jean-Denis Docquier

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ACS Chemical Biology
DOI: 10.1021/cb500703p
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Hsp90 C-Terminal Inhibitors Exhibit Antimigratory Activity by Disrupting the Hsp90α/Aha1 Complex in PC3-MM2 Cells

December 3rd, 2014 by Suman Ghosh, Heather E. Shinogle, Gaurav Garg, George A. Vielhauer, Jeffrey M. Holzbeierlein, Rick T. Dobrowsky and Brian S. J. Blagg

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ACS Chemical Biology
DOI: 10.1021/cb5008713
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Inhibition of CDC25B Phosphatase Through Disruption of Protein–Protein Interaction

December 1st, 2014 by George Lund, Sergii Dudkin, Dmitry Borkin, Wendi Ni, Jolanta Grembecka and Tomasz Cierpicki

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ACS Chemical Biology
DOI: 10.1021/cb500883h

Anticancer/Antiviral Agent Akt Inhibitor-IV Massively Accumulates in Mitochondria and Potently Disrupts Cellular Bioenergetics

December 1st, 2014 by J. Matthew Meinig and Blake R. Peterson

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ACS Chemical Biology
DOI: 10.1021/cb500856c
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Synthesis and Biological Evaluation of Optimized Inhibitors of the Mitotic Kinesin Kif18A

November 26th, 2014 by Joachim Braun, Martin M. Möckel, Tobias Strittmatter, Andreas Marx, Ulrich Groth and Thomas U. Mayer

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ACS Chemical Biology
DOI: 10.1021/cb500789h