An Evolved Mxe GyrA Intein for Enhanced Production of Fusion Proteins

November 24th, 2014 by Carrie J. Marshall, Vanessa A. Grosskopf, Taylor J. Moehling, Benjamin J. Tillotson, Gregory J. Wiepz, Nicholas L. Abbott, Ronald T. Raines and Eric V. Shusta

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ACS Chemical Biology
DOI: 10.1021/cb500689g

Sequence-Specific Generation of 1,N6-Ethenoadenine and 3,N4-Ethenocytosine in Single-Stranded Unmodified DNA

November 24th, 2014 by David Egloff, Igor A. Oleinich and Eva Freisinger

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ACS Chemical Biology
DOI: 10.1021/cb500497p
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Sequence-Specific Generation of 1,N6-Ethenoadenine and 3,N4-Ethenocytosine in Single-Stranded Unmodified DNA

Fluorogen-Activating Proteins Provide Tunable Labeling Densities for Tracking FcεRI Independent of IgE

November 24th, 2014 by Samantha L. Schwartz, Qi Yan, Cheryl A. Telmer, Keith A. Lidke, Marcel P. Bruchez and Diane S. Lidke

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ACS Chemical Biology
DOI: 10.1021/cb5005146
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Fluorogen-Activating Proteins Provide Tunable Labeling Densities for Tracking FcεRI Independent of IgE

Understanding Dengue Virus Capsid Protein Disordered N-Terminus and pep14-23-Based Inhibition

November 20th, 2014 by André F. Faustino, Gabriela M. Guerra, Roland G. Huber, Axel Hollmann, Marco M. Domingues, Glauce M. Barbosa, Francisco J. Enguita, Peter J. Bond, Miguel A. R. B. Castanho, Andrea T. Da Poian, Fabio C. L. Almeida, Nuno C. Santos and Ivo C. Martins

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ACS Chemical Biology
DOI: 10.1021/cb500640t

Drugging Sphingosine Kinases

November 19th, 2014 by Webster L. Santos and Kevin R. Lynch

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ACS Chemical Biology
DOI: 10.1021/cb5008426

Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes

November 19th, 2014 by Sarah A. Scott, Cierra T. Spencer, Matthew C. O’Reilly, Kyle A. Brown, Robert R. Lavieri, Chul-Hee Cho, Dai-Il Jung, Richard C. Larock, H. Alex Brown and Craig W. Lindsley

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ACS Chemical Biology
DOI: 10.1021/cb500828m
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Discovery of Desketoraloxifene Analogues as Inhibitors of Mammalian, Pseudomonas aeruginosa, and NAPE Phospholipase D Enzymes

Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate

November 18th, 2014 by Jing Fan, Xin Teng, Ling Liu, Katherine R. Mattaini, Ryan E. Looper, Matthew G. Vander Heiden and Joshua D. Rabinowitz

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ACS Chemical Biology
DOI: 10.1021/cb500683c

Structural Details of Light Activation of the LOV2-based Photoswitch PA-Rac1

November 17th, 2014 by Andreas Winkler, Thomas R. M. Barends, Anikó Udvarhelyi, Daniel Lenherr-Frey, Lukas Lomb, Andreas Menzel and Ilme Schlichting

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ACS Chemical Biology
DOI: 10.1021/cb500744m

Revealing Structural Changes of Prion Protein during Conversion from α-Helical Monomer to β-Oligomers by Means of ESR and Nanochannel Encapsulation

November 14th, 2014 by Che Yang, Wei-Lin Lo, Yun-Hsuan Kuo, Jason C. Sang, Chung-Yu Lee, Yun-Wei Chiang and Rita P.-Y. Chen

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ACS Chemical Biology
DOI: 10.1021/cb500765e
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Revealing Structural Changes of Prion Protein during Conversion from α-Helical Monomer to β-Oligomers by Means of ESR and Nanochannel Encapsulation

Sulfhydryl-Specific Probe for Monitoring Protein Redox Sensitivity

November 14th, 2014 by Jae-Jin Lee, Sura Ha, Hee-Jung Kim, Hyun Joo Ha, Hee-Yoon Lee and Kong-Joo Lee

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ACS Chemical Biology
DOI: 10.1021/cb500839j