Allele-Specific Chemical Genetics: Concept, Strategies, and Applications

December 12th, 2014 by Kabirul Islam

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ACS Chemical Biology
DOI: 10.1021/cb500651d

Binding of Human Proteins to Amyloid-β Protofibrils

December 12th, 2014 by M. Mahafuzur Rahman, Henrik Zetterberg, Christofer Lendel and Torleif Härd

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ACS Chemical Biology
DOI: 10.1021/cb5008663

Single Asparagine to Arginine Mutation Allows PerR to Switch from PerR Box to Fur Box

December 11th, 2014 by Christelle Caux-Thang, Aubérie Parent, Ramakrishnan Sethu, Arhamatoulaye Maïga, Geneviève Blondin, Jean-Marc Latour and Victor Duarte

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ACS Chemical Biology
DOI: 10.1021/cb500783g

Detection of Tumor-Associated Glycopeptides by Lectins: The Peptide Context Modulates Carbohydrate Recognition

December 10th, 2014 by David Madariaga, Nuria Martínez-Sáez, Víctor J. Somovilla, Helena Coelho, Jessika Valero-González, Jorge Castro-López, Juan L. Asensio, Jesús Jiménez-Barbero, Jesús H. Busto, Alberto Avenoza, Filipa Marcelo, Ramón Hurtado-Guerrero, Francisco

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ACS Chemical Biology
DOI: 10.1021/cb500855x
  • Posted in ACS Chemical Biology, Publications
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2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1

December 9th, 2014 by João Neres, Ruben C. Hartkoorn, Laurent R. Chiarelli, Ramakrishna Gadupudi, Maria Rosalia Pasca, Giorgia Mori, Alberto Venturelli, Svetlana Savina, Vadim Makarov, Gaelle S. Kolly, Elisabetta Molteni, Claudia Binda, Neeraj Dhar, Stefania Ferrari, Pri

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ACS Chemical Biology
DOI: 10.1021/cb5007163

DFGmodel: Predicting Protein Kinase Structures in Inactive States for Structure-Based Discovery of Type-II Inhibitors

December 9th, 2014 by Peter Man-Un Ung and Avner Schlessinger

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ACS Chemical Biology
DOI: 10.1021/cb500696t
  • Posted in ACS Chemical Biology, Publications
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Protein Prenylation: Enzymes, Therapeutics, and Biotechnology Applications

December 8th, 2014 by Charuta C. Palsuledesai and Mark D. Distefano

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ACS Chemical Biology
DOI: 10.1021/cb500791f

Acetylation of Trehalose Mycolates Is Required for Efficient MmpL-Mediated Membrane Transport in Corynebacterineae

December 8th, 2014 by Yoshiki Yamaryo-Botte, Arek K. Rainczuk, David J. Lea-Smith, Rajini Brammananth, Phillip L. van der Peet, Peter Meikle, Julie E. Ralton, Thusita W. T. Rupasinghe, Spencer J. Williams, Ross L. Coppel, Paul K. Crellin and Malcolm J. McConville

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ACS Chemical Biology
DOI: 10.1021/cb5007689
  • Posted in ACS Chemical Biology, Publications
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Directed Evolution of New and Improved Enzyme Functions Using an Evolutionary Intermediate and Multidirectional Search

December 5th, 2014 by Joanne L. Porter, Priscilla L. S. Boon, Tracy P. Murray, Thomas Huber, Charles A. Collyer and David L. Ollis

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ACS Chemical Biology
DOI: 10.1021/cb500809f
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Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

December 5th, 2014 by Nan Zhao, Crystal M. Darby, Jennifer Small, Daniel A. Bachovchin, Xiuju Jiang, Kristin E. Burns-Huang, Helene Botella, Sabine Ehrt, Dale L. Boger, Erin D. Anderson, Benjamin F. Cravatt, Anna E. Speers, Virneliz Fernandez-Vega, Peter S. Hodder, Christ

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ACS Chemical Biology
DOI: 10.1021/cb500746z
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