Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1

January 6th, 2015 by Min Luo, Kent S. Gates, Michael T. Henzl and John J. Tanner

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ACS Chemical Biology
DOI: 10.1021/cb500977q

Interactions of the Natural Product (+)-Avrainvillamide with Nucleophosmin and Exportin-1 Mediate the Cellular Localization of Nucleophosmin and its AML-Associated Mutants

January 5th, 2015 by Herschel Mukherjee, Kok-Ping Chan, Vibeke Andresen, Mariah L. Hanley, Bjørn Tore Gjertsen and Andrew G. Myers

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ACS Chemical Biology
DOI: 10.1021/cb500872g
  • Posted in ACS Chemical Biology, Publications
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Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes

January 5th, 2015 by Ross W. Cheloha, Jeremy A. Sullivan, Tong Wang, Jordan M. Sand, John Sidney, Alessandro Sette, Mark E. Cook, M. Suresh and Samuel H. Gellman

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ACS Chemical Biology
DOI: 10.1021/cb500888q
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Unexpected Off-Targets and Paradoxical Pathway Activation by Kinase Inhibitors

January 2nd, 2015 by Oliver Hantschel

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ACS Chemical Biology
DOI: 10.1021/cb500886n

Computational Design of a Time-Dependent Histone Deacetylase 2 Selective Inhibitor

January 2nd, 2015 by Jingwei Zhou, Min Li, Nanhao Chen, Shenglong Wang, Hai-Bin Luo, Yingkai Zhang and Ruibo Wu

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ACS Chemical Biology
DOI: 10.1021/cb500767c

Effective GTP-Replacing FtsZ Inhibitors and Antibacterial Mechanism of Action

December 30th, 2014 by Marta Artola, Laura B. Ruiz-Avila, Albert Vergoñós, Sonia Huecas, Lidia Araujo-Bazán, Mar Martín-Fontecha, Henar Vázquez-Villa, Carlos Turrado, Erney Ramírez-Aportela, Annabelle Hoegl, Matthew Nodwell, Isabel Barasoain, Pablo Chacón, Stephan A

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ACS Chemical Biology
DOI: 10.1021/cb500974d

Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals

December 30th, 2014 by Thillai V. Sekar, Kira Foygel, Rammohan Devulapally and Ramasamy Paulmurugan

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ACS Chemical Biology
DOI: 10.1021/cb5008037
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Topology Specific Stabilization of Promoter over Telomeric G-Quadruplex DNAs by Bisbenzimidazole Carboxamide Derivatives

December 26th, 2014 by V. Dhamodharan, S. Harikrishna, Achikanath C. Bhasikuttan and P. I. Pradeepkumar

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ACS Chemical Biology
DOI: 10.1021/cb5008597
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Bacterial Histidine Kinases as Novel Antibacterial Drug Targets

December 26th, 2014 by Agnieszka E. Bem, Nadya Velikova, M. Teresa Pellicer, Peter van Baarlen, Alberto Marina and Jerry M. Wells

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ACS Chemical Biology
DOI: 10.1021/cb5007135

Classification of Chemical Chaperones Based on Their Effect on Protein Folding Landscapes

December 23rd, 2014 by Rohan Dandage, Anannya Bandyopadhyay, Gopal Gunanathan Jayaraj, Kanika Saxena, Vijit Dalal, Aritri Das and Kausik Chakraborty

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ACS Chemical Biology
DOI: 10.1021/cb500798y