Detection of Tumor-Associated Glycopeptides by Lectins: The Peptide Context Modulates Carbohydrate Recognition

December 10th, 2014 by David Madariaga, Nuria Martínez-Sáez, Víctor J. Somovilla, Helena Coelho, Jessika Valero-González, Jorge Castro-López, Juan L. Asensio, Jesús Jiménez-Barbero, Jesús H. Busto, Alberto Avenoza, Filipa Marcelo, Ramón Hurtado-Guerrero, Francisco

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ACS Chemical Biology
DOI: 10.1021/cb500855x
  • Posted in ACS Chemical Biology, Publications
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2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1

December 9th, 2014 by João Neres, Ruben C. Hartkoorn, Laurent R. Chiarelli, Ramakrishna Gadupudi, Maria Rosalia Pasca, Giorgia Mori, Alberto Venturelli, Svetlana Savina, Vadim Makarov, Gaelle S. Kolly, Elisabetta Molteni, Claudia Binda, Neeraj Dhar, Stefania Ferrari, Pri

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ACS Chemical Biology
DOI: 10.1021/cb5007163

DFGmodel: Predicting Protein Kinase Structures in Inactive States for Structure-Based Discovery of Type-II Inhibitors

December 9th, 2014 by Peter Man-Un Ung and Avner Schlessinger

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ACS Chemical Biology
DOI: 10.1021/cb500696t
  • Posted in ACS Chemical Biology, Publications
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Protein Prenylation: Enzymes, Therapeutics, and Biotechnology Applications

December 8th, 2014 by Charuta C. Palsuledesai and Mark D. Distefano

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ACS Chemical Biology
DOI: 10.1021/cb500791f

Acetylation of Trehalose Mycolates Is Required for Efficient MmpL-Mediated Membrane Transport in Corynebacterineae

December 8th, 2014 by Yoshiki Yamaryo-Botte, Arek K. Rainczuk, David J. Lea-Smith, Rajini Brammananth, Phillip L. van der Peet, Peter Meikle, Julie E. Ralton, Thusita W. T. Rupasinghe, Spencer J. Williams, Ross L. Coppel, Paul K. Crellin and Malcolm J. McConville

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ACS Chemical Biology
DOI: 10.1021/cb5007689
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Directed Evolution of New and Improved Enzyme Functions Using an Evolutionary Intermediate and Multidirectional Search

December 5th, 2014 by Joanne L. Porter, Priscilla L. S. Boon, Tracy P. Murray, Thomas Huber, Charles A. Collyer and David L. Ollis

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ACS Chemical Biology
DOI: 10.1021/cb500809f
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Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

December 5th, 2014 by Nan Zhao, Crystal M. Darby, Jennifer Small, Daniel A. Bachovchin, Xiuju Jiang, Kristin E. Burns-Huang, Helene Botella, Sabine Ehrt, Dale L. Boger, Erin D. Anderson, Benjamin F. Cravatt, Anna E. Speers, Virneliz Fernandez-Vega, Peter S. Hodder, Christ

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ACS Chemical Biology
DOI: 10.1021/cb500746z
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Interfacing Chemical Biology and Drug Discovery: Report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2–4, 2014, Rouen, France

December 5th, 2014 by Janos Sapi, Frédéric Schmidt, Luc Van Hijfte and Pascal George

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ACS Chemical Biology
DOI: 10.1021/cb5009469
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Identifying Modulators of CXC Receptors 3 and 4 with Tailored Selectivity Using Multi-Target Docking

December 5th, 2014 by Denis Schmidt, Viachaslau Bernat, Regine Brox, Nuska Tschammer and Peter Kolb

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ACS Chemical Biology
DOI: 10.1021/cb500577j
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Probing Interactions between Lysine Residues in Histone Tails and Nucleosomal DNA via Product and Kinetic Analysis

December 5th, 2014 by Liwei Weng, Chuanzheng Zhou and Marc M. Greenberg

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ACS Chemical Biology
DOI: 10.1021/cb500737y
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