An Alternate Pathway of Arsenate Resistance in E. coli Mediated by the Glutathione S-Transferase GstB

January 7th, 2015 by Constantine Chrysostomou, Erik M. Quandt, Nicholas M. Marshall, Everett Stone and George Georgiou

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ACS Chemical Biology
DOI: 10.1021/cb500755j
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Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors

January 6th, 2015 by Michael B. Lazarus, Chris J. Novotny and Kevan M. Shokat

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ACS Chemical Biology
DOI: 10.1021/cb500835z

Quantitative Imaging of Glutathione in Live Cells Using a Reversible Reaction-Based Ratiometric Fluorescent Probe

January 6th, 2015 by Xiqian Jiang, Yong Yu, Jianwei Chen, Mingkun Zhao, Hui Chen, Xianzhou Song, Alexander J. Matzuk, Shaina L. Carroll, Xiao Tan, Antons Sizovs, Ninghui Cheng, Meng C. Wang and Jin Wang

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ACS Chemical Biology
DOI: 10.1021/cb500986w
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Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1

January 6th, 2015 by Min Luo, Kent S. Gates, Michael T. Henzl and John J. Tanner

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ACS Chemical Biology
DOI: 10.1021/cb500977q

Interactions of the Natural Product (+)-Avrainvillamide with Nucleophosmin and Exportin-1 Mediate the Cellular Localization of Nucleophosmin and its AML-Associated Mutants

January 5th, 2015 by Herschel Mukherjee, Kok-Ping Chan, Vibeke Andresen, Mariah L. Hanley, Bjørn Tore Gjertsen and Andrew G. Myers

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ACS Chemical Biology
DOI: 10.1021/cb500872g
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Consequences of Periodic α-to-β3 Residue Replacement for Immunological Recognition of Peptide Epitopes

January 5th, 2015 by Ross W. Cheloha, Jeremy A. Sullivan, Tong Wang, Jordan M. Sand, John Sidney, Alessandro Sette, Mark E. Cook, M. Suresh and Samuel H. Gellman

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ACS Chemical Biology
DOI: 10.1021/cb500888q
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Unexpected Off-Targets and Paradoxical Pathway Activation by Kinase Inhibitors

January 2nd, 2015 by Oliver Hantschel

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ACS Chemical Biology
DOI: 10.1021/cb500886n

Computational Design of a Time-Dependent Histone Deacetylase 2 Selective Inhibitor

January 2nd, 2015 by Jingwei Zhou, Min Li, Nanhao Chen, Shenglong Wang, Hai-Bin Luo, Yingkai Zhang and Ruibo Wu

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ACS Chemical Biology
DOI: 10.1021/cb500767c

Effective GTP-Replacing FtsZ Inhibitors and Antibacterial Mechanism of Action

December 30th, 2014 by Marta Artola, Laura B. Ruiz-Avila, Albert Vergoñós, Sonia Huecas, Lidia Araujo-Bazán, Mar Martín-Fontecha, Henar Vázquez-Villa, Carlos Turrado, Erney Ramírez-Aportela, Annabelle Hoegl, Matthew Nodwell, Isabel Barasoain, Pablo Chacón, Stephan A

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ACS Chemical Biology
DOI: 10.1021/cb500974d

Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals

December 30th, 2014 by Thillai V. Sekar, Kira Foygel, Rammohan Devulapally and Ramasamy Paulmurugan

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ACS Chemical Biology
DOI: 10.1021/cb5008037
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