Ironing out Their Differences: Dissecting the Structural Determinants of a Phenylalanine Aminomutase and Ammonia Lyase

January 20th, 2015 by Matthew M. Heberling, Marcelo F. Masman, Sebastian Bartsch, Gjalt G. Wybenga, Bauke W. Dijkstra, Siewert J. Marrink and Dick B. Janssen

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500794h
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Ironing out Their Differences: Dissecting the Structural Determinants of a Phenylalanine Aminomutase and Ammonia Lyase

Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival

January 20th, 2015 by Jae Won Chang, Andrea M. Zuhl, Anna E. Speers, Sherry Niessen, Steven J. Brown, Melinda M. Mulvihill, Yi Chiao Fan, Timothy P. Spicer, Mark Southern, Louis Scampavia, Virneliz Fernandez-Vega, Melissa M. Dix, Michael D. Cameron, Peter S. Hodder, Hugh

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500893q
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival

Genetically Encoding Lysine Modifications on Histone H4

January 20th, 2015 by Bryan J. Wilkins, Liljan E. Hahn, Svenja Heitmüller, Holm Frauendorf, Oliver Valerius, Gerhard H. Braus and Heinz Neumann

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb501011v

Manganese and Microbial Pathogenesis: Sequestration by the Mammalian Immune System and Utilization by Microorganisms

January 16th, 2015 by Megan Brunjes Brophy and Elizabeth M. Nolan

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500792b
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Manganese and Microbial Pathogenesis: Sequestration by the Mammalian Immune System and Utilization by Microorganisms

Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling

January 15th, 2015 by Lu Wei, Yihui Shen, Fang Xu, Fanghao Hu, Jamie K. Harrington, Kimara L. Targoff and Wei Min

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500787b
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling

Solution Structure, Aggregation Behavior, and Flexibility of Human Relaxin-2

January 15th, 2015 by Linda M. Haugaard-Kedström, Mohammed Akhter Hossain, Norelle L. Daly, Ross A. D. Bathgate, Ernst Rinderknecht, John D. Wade, David J. Craik and K. Johan Rosengren

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500918v

Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement

January 15th, 2015 by Joanna S. Yi, Alexander J. Federation, Jun Qi, Sirano Dhe-Paganon, Michael Hadler, Xiang Xu, Roodolph St. Pierre, Anthony C. Varca, Lei Wu, Jason J. Marineau, William B. Smith, Amanda Souza, Emma J. Chory, Scott A. Armstrong and James E. Bradner

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500796d

Structural Basis for Regulation of RNA-Binding Proteins by Phosphorylation

January 14th, 2015 by Roopa Thapar

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500860x

Determination of the Formylglycinamide Ribonucleotide Amidotransferase Ammonia Pathway by Combining 3D-RISM Theory with Experiment

January 14th, 2015 by Ajay S. Tanwar, Daniel J. Sindhikara, Fumio Hirata and Ruchi Anand

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb501015r
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Determination of the Formylglycinamide Ribonucleotide Amidotransferase Ammonia Pathway by Combining 3D-RISM Theory with Experiment

HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells

January 8th, 2015 by Jonathan Iaconelli, Joanne H. Huang, Shaunna S. Berkovitch, Shrikanta Chattopadhyay, Ralph Mazitschek, Stuart L. Schreiber, Stephen J. Haggarty and Rakesh Karmacharya

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/cb500838r
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells