Chemical Cross-Linking/Mass Spectrometry Maps the Amyloid β Peptide Binding Region on Both Apolipoprotein E Domains

January 21st, 2015 by Stéphanie Deroo, Florian Stengel, Azadeh Mohammadi, Nicolas Henry, Ellen Hubin, Eva-Maria Krammer, Ruedi Aebersold and Vincent Raussens

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ACS Chemical Biology
DOI: 10.1021/cb500994j
  • Posted in ACS Chemical Biology, Publications
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Modulation of Alternative Splicing with Chemical Compounds in New Therapeutics for Human Diseases

January 20th, 2015 by Kenji Ohe and Masatoshi Hagiwara

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ACS Chemical Biology
DOI: 10.1021/cb500697f
  • Posted in ACS Chemical Biology, Publications
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Saturation Mutagenesis of TsrA Ala4 Unveils a Highly Mutable Residue of Thiostrepton A

January 20th, 2015 by Feifei Zhang and Wendy L. Kelly

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ACS Chemical Biology
DOI: 10.1021/cb5007745

Ironing out Their Differences: Dissecting the Structural Determinants of a Phenylalanine Aminomutase and Ammonia Lyase

January 20th, 2015 by Matthew M. Heberling, Marcelo F. Masman, Sebastian Bartsch, Gjalt G. Wybenga, Bauke W. Dijkstra, Siewert J. Marrink and Dick B. Janssen

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ACS Chemical Biology
DOI: 10.1021/cb500794h
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Selective Inhibitor of Platelet-Activating Factor Acetylhydrolases 1b2 and 1b3 That Impairs Cancer Cell Survival

January 20th, 2015 by Jae Won Chang, Andrea M. Zuhl, Anna E. Speers, Sherry Niessen, Steven J. Brown, Melinda M. Mulvihill, Yi Chiao Fan, Timothy P. Spicer, Mark Southern, Louis Scampavia, Virneliz Fernandez-Vega, Melissa M. Dix, Michael D. Cameron, Peter S. Hodder, Hugh

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ACS Chemical Biology
DOI: 10.1021/cb500893q
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Genetically Encoding Lysine Modifications on Histone H4

January 20th, 2015 by Bryan J. Wilkins, Liljan E. Hahn, Svenja Heitmüller, Holm Frauendorf, Oliver Valerius, Gerhard H. Braus and Heinz Neumann

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ACS Chemical Biology
DOI: 10.1021/cb501011v

Manganese and Microbial Pathogenesis: Sequestration by the Mammalian Immune System and Utilization by Microorganisms

January 16th, 2015 by Megan Brunjes Brophy and Elizabeth M. Nolan

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ACS Chemical Biology
DOI: 10.1021/cb500792b
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Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling

January 15th, 2015 by Lu Wei, Yihui Shen, Fang Xu, Fanghao Hu, Jamie K. Harrington, Kimara L. Targoff and Wei Min

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ACS Chemical Biology
DOI: 10.1021/cb500787b
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Solution Structure, Aggregation Behavior, and Flexibility of Human Relaxin-2

January 15th, 2015 by Linda M. Haugaard-Kedström, Mohammed Akhter Hossain, Norelle L. Daly, Ross A. D. Bathgate, Ernst Rinderknecht, John D. Wade, David J. Craik and K. Johan Rosengren

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ACS Chemical Biology
DOI: 10.1021/cb500918v

Structure-Guided DOT1L Probe Optimization by Label-Free Ligand Displacement

January 15th, 2015 by Joanna S. Yi, Alexander J. Federation, Jun Qi, Sirano Dhe-Paganon, Michael Hadler, Xiang Xu, Roodolph St. Pierre, Anthony C. Varca, Lei Wu, Jason J. Marineau, William B. Smith, Amanda Souza, Emma J. Chory, Scott A. Armstrong and James E. Bradner

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ACS Chemical Biology
DOI: 10.1021/cb500796d