Computational Design and Experimental Characterization of Peptides Intended for pH-Dependent Membrane Insertion and Pore Formation

January 28th, 2015 by Yao Zhang, René Bartz, Gevorg Grigoryan, Michael Bryant, Jeff Aaronson, Stephen Beck, Nathalie Innocent, Lee Klein, William Procopio, Tom Tucker, Vasant Jadhav, David M. Tellers and William F. DeGrado

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ACS Chemical Biology
DOI: 10.1021/cb500759p
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Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1

January 28th, 2015 by Michael T. Perfetti, Brandi M. Baughman, Bradley M. Dickson, Yunxiang Mu, Gaofeng Cui, Pavel Mader, Aiping Dong, Jacqueline L. Norris, Scott B. Rothbart, Brian D. Strahl, Peter J. Brown, William P. Janzen, Cheryl H. Arrowsmith, Georges Mer, Kevin M.

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ACS Chemical Biology
DOI: 10.1021/cb500956g
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Genetic Targeting of a Small Fluorescent Zinc Indicator to Cell Surface for Monitoring Zinc Secretion

January 27th, 2015 by Daliang Li, Lin Liu and Wen-Hong Li

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ACS Chemical Biology
DOI: 10.1021/cb5007536
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Small Molecule Inhibitors of Disulfide Bond Formation by the Bacterial DsbA–DsbB Dual Enzyme System

January 27th, 2015 by Maria A. Halili, Prabhakar Bachu, Fredrik Lindahl, Chérine Bechara, Biswaranjan Mohanty, Robert C. Reid, Martin J. Scanlon, Carol V. Robinson, David P. Fairlie and Jennifer L. Martin

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ACS Chemical Biology
DOI: 10.1021/cb500988r
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Stereospecific Phosphorylation by the Central Mitotic Kinase Cdk1-Cyclin B

January 26th, 2015 by Felicia A. Etzkorn and Song Zhao

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ACS Chemical Biology
DOI: 10.1021/cb500815b

Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design

January 26th, 2015 by Daniel J. Slade, Pengfei Fang, Christina J. Dreyton, Ying Zhang, Jakob Furhmann, Don Rempel, Benjamin D. Bax, Scott A. Coonrod, Huw D. Lewis, Min Guo, Michael L. Gross and Paul R. Thompson

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ACS Chemical Biology
DOI: 10.1021/cb500933j
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Family of Class I Lantibiotics from Actinomycetes and Improvement of Their Antibacterial Activities

January 23rd, 2015 by Sonia I. Maffioli, Paolo Monciardini, Bruno Catacchio, Carlo Mazzetti, Daniela Münch, Cristina Brunati, Hans-Georg Sahl and Stefano Donadio

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ACS Chemical Biology
DOI: 10.1021/cb500878h
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The Elastase-PK101 Structure: Mechanism of an Ultrasensitive Activity-based Probe Revealed

January 22nd, 2015 by Bernhard C. Lechtenberg, Paulina Kasperkiewicz, Howard Robinson, Marcin Drag and Stefan J. Riedl

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ACS Chemical Biology
DOI: 10.1021/cb500909n

Critical Evaluation and Rate Constants of Chemoselective Ligation Reactions for Stoichiometric Conjugations in Water

January 22nd, 2015 by Fumito Saito, Hidetoshi Noda and Jeffrey W. Bode

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ACS Chemical Biology
DOI: 10.1021/cb5006728
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Structural and Functional Analysis of the Loading Acyltransferase from Avermectin Modular Polyketide Synthase

January 22nd, 2015 by Fen Wang, Yanjie Wang, Junjie Ji, Zhan Zhou, Jingkai Yu, Hua Zhu, Zhiguo Su, Lixin Zhang and Jianting Zheng

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ACS Chemical Biology
DOI: 10.1021/cb500873k
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