Rapid Synthesis, RNA Binding, and Antibacterial Screening of a Peptidic-Aminosugar (PA) Library

February 23rd, 2015 by Liuwei Jiang, Derrick Watkins, Yi Jin, Changjun Gong, Ada King, Arren Z. Washington, Keith D. Green, Sylvie Garneau-Tsodikova, Adegboyega K. Oyelere and Dev P. Arya

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ACS Chemical Biology
DOI: 10.1021/cb5010367

HIV Protease Inhibitors Block Streptolysin S Production

February 20th, 2015 by Tucker Maxson, Caitlin D. Deane, Evelyn M. Molloy, Courtney L. Cox, Andrew L. Markley, Shaun W. Lee and Douglas A. Mitchell

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ACS Chemical Biology
DOI: 10.1021/cb500843r

Mechanism of Scrapie Prion Precipitation with Phosphotungstate Anions

February 19th, 2015 by Dana J. Levine, Jan Stöhr, Lillian E. Falese, Julian Ollesch, Holger Wille, Stanley B. Prusiner and Jeffrey R. Long

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ACS Chemical Biology
DOI: 10.1021/cb5006239

Indole-based Cyanine as a Nuclear RNA-Selective Two-Photon Fluorescent Probe for Live Cell Imaging

February 19th, 2015 by Lei Guo, Miu Shan Chan, Di Xu, Dick Yan Tam, Frédéric Bolze, Pik Kwan Lo and Man Shing Wong

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ACS Chemical Biology
DOI: 10.1021/cb500927r
  • Posted in ACS Chemical Biology, Publications
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Human Phospholipase D Activity Transiently Regulates Pyrimidine Biosynthesis in Malignant Gliomas

February 17th, 2015 by Thomas P. Mathews, Salisha Hill, Kristie L. Rose, Pavlina T. Ivanova, Craig W. Lindsley and H. Alex Brown

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ACS Chemical Biology
DOI: 10.1021/cb500772c
  • Posted in ACS Chemical Biology, Publications
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Swapped-Domain Constructs of the Glycoprotein-41 Ectodomain Are Potent Inhibitors of HIV Infection

February 17th, 2015 by Shidong Chu, Hardeep Kaur, Ariana Nemati, Joseph D. Walsh, Vivian Partida, Shao-Qing Zhang and Miriam Gochin

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ACS Chemical Biology
DOI: 10.1021/cb501021j
  • Posted in ACS Chemical Biology, Publications
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Rapid, Specific, No-wash, Far-red Fluorogen Activation in Subcellular Compartments by Targeted Fluorogen Activating Proteins

February 16th, 2015 by Cheryl A. Telmer, Richa Verma, Haibing Teng, Susan Andreko, Leann Law and Marcel P. Bruchez

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ACS Chemical Biology
DOI: 10.1021/cb500957k
  • Posted in ACS Chemical Biology, Publications
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Biophysical and Biological Characterization of Hairpin and Molecular Beacon RNase H Active Antisense Oligonucleotides

February 13th, 2015 by Michael E. Østergaard, George Thomas, Erich Koller, Amber L. Southwell, Michael R. Hayden and Punit P. Seth

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ACS Chemical Biology
DOI: 10.1021/cb500880f
  • Posted in ACS Chemical Biology, Publications
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Insights into Methyltransferase Specificity and Bioactivity of Derivatives of the Antibiotic Plantazolicin

February 11th, 2015 by Yue Hao, Patricia M. Blair, Abhishek Sharma, Douglas A. Mitchell and Satish K. Nair

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ACS Chemical Biology
DOI: 10.1021/cb501042a
  • Posted in ACS Chemical Biology, Publications
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Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines

February 9th, 2015 by Da Duan, Allison K. Doak, Lyudmila Nedyalkova and Brian K. Shoichet

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ACS Chemical Biology
DOI: 10.1021/cb5009487