Starter Unit Flexibility for Engineered Product Synthesis by the Nonreducing Polyketide Synthase PksA

March 10th, 2015 by Callie R. Huitt-Roehl, Eric A. Hill, Martina M. Adams, Anna L. Vagstad, Jesse W. Li and Craig A. Townsend

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00005
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Michael-Type Cyclizations in Lantibiotic Biosynthesis Are Reversible

March 10th, 2015 by Xiao Yang and Wilfred A. van der Donk

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ACS Chemical Biology
DOI: 10.1021/acschembio.5b00007

Chemically-Modified Peptides Targeting the PDZ Domain of GIPC as a Therapeutic Approach for Cancer

March 9th, 2015 by Chitta Ranjan Patra, Chamila N. Rupasinghe, Shamit K. Dutta, Santanu Bhattacharya, Enfeng Wang, Mark R. Spaller and Debabrata Mukhopadhyay

ACS Chemical Biology
DOI: 10.1021/cb500865a
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Molecular Engineering of Nonmetallic Biosensors for CEST MRI

March 9th, 2015 by Amnon Bar-Shir, Jeff W. M. Bulte and Assaf A. Gilad

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ACS Chemical Biology
DOI: 10.1021/cb500923v

Solvatochromic Nile Red Probes with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

March 6th, 2015 by Rémy Kreder, Kyrylo A. Pyrshev, Zeinab Darwich, Oleksandr A. Kucherak, Yves Mély and Andrey S. Klymchenko

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ACS Chemical Biology
DOI: 10.1021/cb500922m
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siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes

March 2nd, 2015 by Shigeo Matsuda, Kristofer Keiser, Jayaprakash K. Nair, Klaus Charisse, Rajar M. Manoharan, Philip Kretschmer, Chang G. Peng, Alexander V. Kel’in, Pachamuthu Kandasamy, Jennifer L.S. Willoughby, Abigail Liebow, William Querbes, Kristina Yucius, Tuyen

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ACS Chemical Biology
DOI: 10.1021/cb501028c
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N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus

February 27th, 2015 by Wenxia Fang, David A. Robinson, Olawale G. Raimi, David E. Blair, Justin R. Harrison, Deborah E. A. Lockhart, Leah S. Torrie, Gian Filippo Ruda, Paul G. Wyatt, Ian H. Gilbert and Daan M. F. van Aalten

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ACS Chemical Biology
DOI: 10.1021/cb5008647

Enantiomers of 3-Methylspermidine Selectively Modulate Deoxyhypusine Synthesis and Reveal Important Determinants for Spermidine Transport

February 27th, 2015 by Mervi T. Hyvönen, Maxim Khomutov, Marine Petit, Janne Weisell, Sergey N. Kochetkov, Leena Alhonen, Jouko Vepsäläinen, Alex R. Khomutov and Tuomo A. Keinänen

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ACS Chemical Biology
DOI: 10.1021/cb500938e
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In This Issue

February 27th, 2015 by Jason G. Underwood

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00129

Structural Basis of Substrate Specificity and Regiochemistry in the MycF/TylF Family of Sugar O-Methyltransferases.

February 26th, 2015 by Steffen M. Bernard, David L. Akey, Ashootosh Tripathi, Sung Ryeol Park, Jamie R. Konwerski, Yojiro Anzai, Shengying Li, Fumio Kato, David H. Sherman and Janet L. Smith

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ACS Chemical Biology
DOI: 10.1021/cb5009348
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