Understanding the Molecular Mechanisms of the CRISPR Toolbox Using Single Molecule Approaches
February 9th, 2018 by Digvijay Singh and Taekjip Ha
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00905
Development of Activity-Based Chemical Probes for Human Sirtuins
February 8th, 2018 by Elysian Graham, Stacia Rymarchyk, Marci Wood and Yana Cen
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00754
Toward a Microparticle-Based System for Pooled Assays of Small Molecules in Cellular Contexts
February 8th, 2018 by Carrie E. Yozwiak, Tal Hirschhorn and Brent R. Stockwell
ACS Chemical Biology
DOI: 10.1021/acschembio.8b00043
Identifying Novel Enhancer Elements with CRISPR-Based Screens
January 10th, 2018 by Jason C. Klein, Wei Chen, Molly Gasperini and Jay Shendure
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00778
Next-Generation DNA-Functionalized Quantum Dots as Biological Sensors
January 4th, 2018 by Ganglin Wang, Zhi Li and Nan Ma
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00887
Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017Utility and Limitations
December 26th, 2017 by Jonathan B. Baell and J. Willem M. Nissink
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00903
Fluorescent Probes of DNA Repair
November 30th, 2017 by David L. Wilson and Eric T. Kool
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00919
Incorporation of β-Amino Acids Enhances the Antifungal Activity and Selectivity of the Helical Antimicrobial Peptide Aurein 1.2
November 30th, 2017 by Myung-Ryul Lee, Namrata Raman, Samuel H. Gellman, David M. Lynn and Sean P. Palecek
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00843
Repair of a Site-Specific DNA Cleavage: Old-School Lessons for Cas9-Mediated Gene Editing
November 14th, 2017 by Danielle N. Gallagher and James E. Haber
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00760
Large Scale Mutational and Kinetic Analysis of a Self-Hydrolyzing Deoxyribozyme
November 3rd, 2017 by V. Dhamodharan, Shungo Kobori and Yohei Yokobayashi
ACS Chemical Biology
DOI: 10.1021/acschembio.7b00621