Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling

July 30th, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00265
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling

Structure–Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity

July 30th, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00495
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Structure–Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity

Kinetics of Ribosome-Catalyzed Polymerization Using Artificial Aminoacyl-tRNA Substrates Clarifies Inefficiencies and Improvements

July 28th, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00335
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Kinetics of Ribosome-Catalyzed Polymerization Using Artificial Aminoacyl-tRNA Substrates Clarifies Inefficiencies and Improvements

Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules

July 27th, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00483
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules

DNA Encoded Library Selections and Insights Provided by Computational Simulations

July 27th, 2015 by Alexander L. Satz

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00378

The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I

July 27th, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00480
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on The Chaperoning Activity of Amino-oxyacetic Acid on Folding-Defective Variants of Human Alanine:Glyoxylate Aminotransferase Causing Primary Hyperoxaluria Type I

A Dual Receptor and Reporter for Multi-Modal Cell Surface Engineering

July 23rd, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00137

Nucleotide Sugar Pucker Preference Mitigates Excision by HIV-1 RT

July 22nd, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00263

L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABAA Receptors

July 21st, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00479
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on L-type Calcium Channel Blockers Enhance Trafficking and Function of Epilepsy-associated α1(D219N) Subunits of GABAA Receptors

Cellular Uptake and Ultrastructural Localization Underlie the Pro-apoptotic Activity of a Hydrocarbon-stapled BIM BH3 Peptide

July 21st, 2015 by

TOC Graphic

ACS Chemical Biology
DOI: 10.1021/acschembio.5b00214
  • Posted in ACS Chemical Biology, Publications
  • Comments Off on Cellular Uptake and Ultrastructural Localization Underlie the Pro-apoptotic Activity of a Hydrocarbon-stapled BIM BH3 Peptide