Structure of N-Formimino-l-glutamate Iminohydrolase from Pseudomonas aeruginosa

January 16th, 2015 by Alexander A. Fedorov, Ricardo Martí-Arbona, Venkatesh V. Nemmara, Daniel Hitchcock, Elena V. Fedorov, Steven C. Almo and Frank M. Raushel

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Biochemistry
DOI: 10.1021/bi501299y

Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes

January 16th, 2015 by Matthew W. Vetting, Nawar Al-Obaidi, Suwen Zhao, Brian San Francisco, Jungwook Kim, Daniel J. Wichelecki, Jason T. Bouvier, Jose O. Solbiati, Hoan Vu, Xinshuai Zhang, Dmitry A. Rodionov, James D. Love, Brandan S. Hillerich, Ronald D. Seidel, Ronald J

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Biochemistry
DOI: 10.1021/bi501388y

Exploring the Mechanisms of the Reductase Activity of Neuroglobin by Site-Directed Mutagenesis of the Heme Distal Pocket

January 16th, 2015 by Jesús Tejero, Courtney E. Sparacino-Watkins, Venkata Ragireddy, Sheila Frizzell and Mark T. Gladwin

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Biochemistry
DOI: 10.1021/bi501196k

Kinetic and Thermodynamic Analyses of Spontaneous Exchange between High-Density Lipoprotein-Bound and Lipid-Free Apolipoprotein A-I

January 16th, 2015 by Daisuke Handa, Hitoshi Kimura, Tatsuya Oka, Yuki Takechi, Keiichiro Okuhira, Michael C. Phillips and Hiroyuki Saito

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Biochemistry
DOI: 10.1021/bi501345j

Effects of Protein Structure on Iron–Polypeptide Vibrational Dynamic Coupling in Cytochrome c

January 16th, 2015 by Mary Grace I. Galinato, Sarah E. J. Bowman, Jesse G. Kleingardner, Sherri Martin, Jiyong Zhao, Wolfgang Sturhahn, Alp, Kara L. Bren and Nicolai Lehnert

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Biochemistry
DOI: 10.1021/bi501430z

Concurrent Cooperativity and Substrate Inhibition in the Epoxidation of Carbamazepine by Cytochrome P450 3A4 Active Site Mutants Inspired by Molecular Dynamics Simulations

January 15th, 2015 by Christian S. Müller, Tim Knehans, Dmitri R. Davydov, Patricia L. Bounds, Ursula von Mandach, James R. Halpert, Amedeo Caflisch and Willem H. Koppenol

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Biochemistry
DOI: 10.1021/bi5011656

Dynamic Architecture of the Purinosome Involved in Human De Novo Purine Biosynthesis

January 15th, 2015 by Minjoung Kyoung, Sarah J. Russell, Casey L. Kohnhorst, Nopondo N. Esemoto and Songon An

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Biochemistry
DOI: 10.1021/bi501480d

New Role for the Ankyrin Repeat Revealed by a Study of the N-Formyltransferase from Providencia alcalifaciens

January 15th, 2015 by Colin R. Woodford, James B. Thoden and Hazel M. Holden

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Biochemistry
DOI: 10.1021/bi501539a

Mutational Analysis of the Ability of Resveratrol To Inhibit Amyloid Formation by Islet Amyloid Polypeptide: Critical Evaluation of the Importance of Aromatic–Inhibitor and Histidine–Inhibitor Interactions

January 15th, 2015 by Ling-Hsien Tu, Lydia M. Young, Amy G. Wong, Alison E. Ashcroft, Sheena E. Radford and Daniel P. Raleigh

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Biochemistry
DOI: 10.1021/bi501016r

Phenotypic Regulation of the Sphingosine 1-Phosphate Receptor Miles Apart by G Protein-Coupled Receptor Kinase 2

January 15th, 2015 by Martina Burczyk, Martin D. Burkhalter, Tamara Blätte, Sabrina Matysik, Marc G. Caron, Lawrence S. Barak and Melanie Philipp

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Biochemistry
DOI: 10.1021/bi501061h