Cholesterol-Induced Lipophobic Interaction between Transmembrane Helices Using Ensemble and Single-Molecule Fluorescence Resonance Energy Transfer

February 6th, 2015 by Yoshiaki Yano, Kotaro Kondo, Ryota Kitani, Arisa Yamamoto and Katsumi Matsuzaki

TOC Graphic

Biochemistry
DOI: 10.1021/bi501528e

Interpretation of pH–Activity Profiles for Acid–Base Catalysis from Molecular Simulations

February 6th, 2015 by Thakshila Dissanayake, Jason M. Swails, Michael E. Harris, Adrian E. Roitberg and Darrin M. York

TOC Graphic

Biochemistry
DOI: 10.1021/bi5012833

Quantitative Biophysical Characterization of Intrinsically Disordered Proteins

February 6th, 2015 by Eric B. Gibbs and Scott A. Showalter

TOC Graphic

Biochemistry
DOI: 10.1021/bi501460a

Thermodynamic Mapping of Effector Protein Interfaces with RalA and RalB

February 5th, 2015 by Louise J. Campbell, Maria Peppa, Michael D. Crabtree, Arooj Shafiq, Nicholas F. McGough, Helen R. Mott and Darerca Owen

TOC Graphic

Biochemistry
DOI: 10.1021/bi501530u

A New General Model for Predicting Melting Thermodynamics of Complementary and Mismatched B-Form Duplexes Containing Locked Nucleic Acids: Application to Probe Design for Digital PCR Detection of Somatic Mutations

February 5th, 2015 by Curtis Hughesman, Kareem Fakhfakh, Roza Bidshahri, H. Louise Lund and Charles Haynes

TOC Graphic

Biochemistry
DOI: 10.1021/bi500905b

Ligand Recognition Specificity of Leukocyte Integrin αMβ2 (Mac-1, CD11b/CD18) and Its Functional Consequences

February 5th, 2015 by Nataly P. Podolnikova, Andriy V. Podolnikov, Thomas A. Haas, Valeryi K. Lishko and Tatiana P. Ugarova

TOC Graphic

Biochemistry
DOI: 10.1021/bi5013782

Disorder-To-Order Transition of MAGI-1 PDZ1 C-Terminal Extension upon Peptide Binding: Thermodynamic and Dynamic Insights

February 3rd, 2015 by Juan Ramírez, Raphaël Recht, Sebastian Charbonnier, Eric Ennifar, R. Andrew Atkinson, Gilles Travé, Yves Nominé and Bruno Kieffer

TOC Graphic

Biochemistry
DOI: 10.1021/bi500845j

Why Does Asn71 Deamidate Faster Than Asn15 in the Enzyme Triosephosphate Isomerase? Answers from Microsecond Molecular Dynamics Simulation and QM/MM Free Energy Calculations

February 3rd, 2015 by Ilke Ugur, Antoine Marion, Viktorya Aviyente and Gerald Monard

TOC Graphic

Biochemistry
DOI: 10.1021/bi5008047

Effect of Interior Loop Length on the Thermal Stability and pKa of i-Motif DNA

February 3rd, 2015 by Samantha M. Reilly, Rhianna K. Morgan, Tracy A. Brooks and Randy M. Wadkins

TOC Graphic

Biochemistry
DOI: 10.1021/bi5014722

Charge and Charge-Pair Mutations Alter the Rate of Assembly and Structural Properties of Apolipoprotein C-II Amyloid Fibrils

February 2nd, 2015 by Yu Mao, Chai Lean Teoh, Shuo Yang, Courtney O. Zlatic, Zachary K. Rosenes, Paul R. Gooley, Geoffrey J. Howlett and Michael D. W. Griffin

TOC Graphic

Biochemistry
DOI: 10.1021/bi5014535