Activity of Quinolone CP-115,955 Against Bacterial and Human Type II Topoisomerases Is Mediated by Different Interactions

January 23rd, 2015 by Katie J. Aldred, Heidi A. Schwanz, Gangqin Li, Benjamin H. Williamson, Sylvia A. McPherson, Charles L. Turnbough, Robert J. Kerns and Neil Osheroff

TOC Graphic

Biochemistry
DOI: 10.1021/bi501073v

Functional and Structural Characterization of an Unusual Cofactor-Independent Oxygenase

January 22nd, 2015 by Bert-Jan Baas, Harshwardhan Poddar, Edzard M. Geertsema, Henriette J. Rozeboom, Marcel P. de Vries, Hjalmar P. Permentier, Andy-Mark W.H. Thunnissen and Gerrit J. Poelarends

TOC Graphic

Biochemistry
DOI: 10.1021/bi501200j

Efficient Delivery of Long-Chain Fatty Aldehydes from the Nostoc punctiforme Acyl–Acyl Carrier Protein Reductase to Its Cognate Aldehyde-Deformylating Oxygenase

January 22nd, 2015 by Douglas M. Warui, Maria-Eirini Pandelia, Lauren J. Rajakovich, Carsten Krebs, J. Martin Bollinger and Squire J. Booker

TOC Graphic

Biochemistry
DOI: 10.1021/bi500847u

Requirements for Mutant and Wild-Type Prion Protein Misfolding In Vitro

January 22nd, 2015 by Geoffrey P. Noble, Daniel J. Walsh, Michael B. Miller, Walker S. Jackson and Surachai Supattapone

TOC Graphic

Biochemistry
DOI: 10.1021/bi501495j

MALDI-TOF MS Lipid Profiles of Cytochrome c Oxidases: Cardiolipin Is Not an Essential Component of the Paracoccus denitrificans Oxidase

January 22nd, 2015 by Rita Vitale, Roberto Angelini, Simona Lobasso, Giuseppe Capitanio, Bernd Ludwig and Angela Corcelli

TOC Graphic

Biochemistry
DOI: 10.1021/bi5008468

Biochemical Characterization of a Pseudomonas aeruginosa Phospholipase D

January 22nd, 2015 by Cierra Spencer and H. Alex Brown

TOC Graphic

Biochemistry
DOI: 10.1021/bi501291t

DNA Charge Transport within the Cell

January 21st, 2015 by Michael A. Grodick, Natalie B. Muren and Jacqueline K. Barton

TOC Graphic

Biochemistry
DOI: 10.1021/bi501520w

Structure–Activity Analysis of Human Ghrelin O-Acyltransferase Reveals Chemical Determinants of Ghrelin Selectivity and Acyl Group Recognition

January 21st, 2015 by Joseph E. Darling, Feifei Zhao, Rosemary J. Loftus, Leslie M. Patton, Richard A. Gibbs and James L. Hougland

TOC Graphic

Biochemistry
DOI: 10.1021/bi5010359

Nickel Superoxide Dismutase: Structural and Functional Roles of His1 and Its H-Bonding Network

January 21st, 2015 by Kelly C. Ryan, Abigail I. Guce, Olivia E. Johnson, Thomas C. Brunold, Diane E. Cabelli, Scott C. Garman and Michael J. Maroney

TOC Graphic

Biochemistry
DOI: 10.1021/bi501258u

Extent of Inhibition of α-Synuclein Aggregation in Vitro by SUMOylation Is Conjugation Site- and SUMO Isoform-Selective

January 21st, 2015 by Tharindumala Abeywardana and Matthew R. Pratt

TOC Graphic

Biochemistry
DOI: 10.1021/bi501512m