Conformational Stability and Catalytic Activity of PTEN Variants Linked to Cancers and Autism Spectrum Disorders

February 13th, 2015 by Sean B. Johnston and Ronald T. Raines

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Biochemistry
DOI: 10.1021/acs.biochem.5b00028

Design of Allosterically Regulated Protein Catalysts

February 12th, 2015 by Olga V. Makhlynets, Elizabeth A. Raymond and Ivan V. Korendovych

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Biochemistry
DOI: 10.1021/bi5015248

Distinguishing the Interactions in the Fructose 1,6-Bisphosphate Binding Site of Human Liver Pyruvate Kinase That Contribute to Allostery

February 12th, 2015 by Arjun Ishwar, Qingling Tang and Aron W. Fenton

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Biochemistry
DOI: 10.1021/bi501426w

Hydrophobic Blocks Facilitate Lipid Compatibility and Translocon Recognition of Transmembrane Protein Sequences

February 12th, 2015 by Tracy A. Stone, Nina Schiller, Gunnar von Heijne and Charles M. Deber

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Biochemistry
DOI: 10.1021/bi5014886

Interplay between Inhibitory Ferric and Stimulatory Curcumin Regulates Phosphorylation-Dependent Human Cystic Fibrosis Transmembrane Conductance Regulator and ΔF508 Activity

February 11th, 2015 by Guangyu Wang

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Biochemistry
DOI: 10.1021/bi501318h

Mode of Binding of the Cyclic Agonist Peptide TC14012 to CXCR7: Identification of Receptor and Compound Determinants

February 11th, 2015 by Nicolas Montpas, Jérôme Cabana, Geneviève St-Onge, Stéphanie Gravel, Geneviève Morin, Tomoko Kuroyanagi, Pierre Lavigne, Nobutaka Fujii, Shinya Oishi and Nikolaus Heveker

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Biochemistry
DOI: 10.1021/bi501526s

Hybrid [FeFe]-Hydrogenases with Modified Active Sites Show Remarkable Residual Enzymatic Activity

February 11th, 2015 by Judith F. Siebel, Agnieszka Adamska-Venkatesh, Katharina Weber, Sigrun Rumpel, Edward Reijerse and Wolfgang Lubitz

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Biochemistry
DOI: 10.1021/bi501391d

Why Ser and Not Thr Brokers Catalysis in the Trypsin Fold

February 11th, 2015 by Leslie A. Pelc, Zhiwei Chen, David W. Gohara, Austin D. Vogt, Nicola Pozzi and Enrico Di Cera

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Biochemistry
DOI: 10.1021/acs.biochem.5b00014

Phosphorylated and Unphosphorylated Serine 13 of CDC37 Stabilize Distinct Interactions between Its Client and HSP90 Binding Domains

February 11th, 2015 by Wenjun Liu and Ralf Landgraf

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Biochemistry
DOI: 10.1021/bi501129g

Self-Assembly of Aqueous Bilirubin Ditaurate, a Natural Conjugated Bile Pigment, to Contraposing Enantiomeric Dimers and M(−) and P(+) Tetramers and Their Selective Hydrophilic Disaggregation by Monomers and Micelles of Bile Salts

February 11th, 2015 by Michael W. Neubrand, Martin C. Carey and Thomas M. Laue

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Biochemistry
DOI: 10.1021/bi501251v