Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-β

March 6th, 2015 by Jun Kuai, Lidia Mosyak, Jon Brooks, Michael Cain, Gregory J. Carven, Shinji Ogawa, Tetsuya Ishino, May Tam, Edward R. Lavallie, Zhiyong Yang, Dirk Ponsel, Robert Rauchenberger, Robert Arch and Nick Pullen

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Biochemistry
DOI: 10.1021/bi5015425

Unlike Catalyzing Error-Free Bypass of 8-OxodGuo, DNA Polymerase λ Is Responsible for a Significant Part of Fapy·dG-Induced G → T Mutations in Human Cells

March 6th, 2015 by Paritosh Pande, Kazuhiro Haraguchi, Yu-Lin Jiang, Marc M. Greenberg and Ashis K. Basu

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Biochemistry
DOI: 10.1021/acs.biochem.5b00119

Structural Basis for Xyloglucan Specificity and α-d-Xylp(1 → 6)-d-Glcp Recognition at the −1 Subsite within the GH5 Family

March 6th, 2015 by Camila Ramos dos Santos, Rosa Lorizolla Cordeiro, Dominic W. S. Wong and Mário Tyago Murakami

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Biochemistry
DOI: 10.1021/acs.biochem.5b00011

Moving Protons and Electrons in Biomimetic Systems

March 5th, 2015 by Jeffrey J. Warren and James M. Mayer

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Biochemistry
DOI: 10.1021/acs.biochem.5b00025

Conformational Difference in Human IgG2 Disulfide Isoforms Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry

March 5th, 2015 by Aming Zhang, Jing Fang, Robert Y.-T. Chou, Pavel V. Bondarenko and Zhongqi Zhang

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Biochemistry
DOI: 10.1021/bi5015216

Effect of Loop Composition on the Stability and Folding Kinetics of RNA Hairpins with Large Loops

March 4th, 2015 by Artem V. Melnykov, Rajesh K. Nayak, Kathleen B. Hall and Alan Van Orden

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Biochemistry
DOI: 10.1021/bi5014276

Detergent-Type Membrane Fragmentation by MSI-78, MSI-367, MSI-594, and MSI-843 Antimicrobial Peptides and Inhibition by Cholesterol: A Solid-State Nuclear Magnetic Resonance Study

March 4th, 2015 by Dong-Kuk Lee, Anirban Bhunia, Samuel A. Kotler and Ayyalusamy Ramamoorthy

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Biochemistry
DOI: 10.1021/bi501418m

Overexpression in Yeast, Photocycle, and in Vitro Structural Change of an Avian Putative Magnetoreceptor Cryptochrome4

March 4th, 2015 by Hiromasa Mitsui, Toshinori Maeda, Chiaki Yamaguchi, Yusuke Tsuji, Ryuji Watari, Yoko Kubo, Keiko Okano and Toshiyuki Okano

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Biochemistry
DOI: 10.1021/bi501441u

Omecamtiv Mecarbil Modulates the Kinetic and Motile Properties of Porcine β-Cardiac Myosin

March 4th, 2015 by Yingying Liu, Howard D. White, Betty Belknap, Donald A. Winkelmann and Eva Forgacs

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Biochemistry
DOI: 10.1021/bi5015166

An Ordered Water Channel in Staphylococcus aureus FabI: Unraveling the Mechanism of Substrate Recognition and Reduction

March 3rd, 2015 by Johannes Schiebel, Andrew Chang, Benjamin Merget, Gopal R. Bommineni, Weixuan Yu, Lauren A. Spagnuolo, Michael V. Baxter, Mona Tareilus, Peter J. Tonge, Caroline Kisker and Christoph A. Sotriffer

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Biochemistry
DOI: 10.1021/bi5014358