Structural Insight into MtmC, a Bifunctional Ketoreductase-Methyltransferase Involved in the Assembly of the Mithramycin Trisaccharide Chain

April 7th, 2015 by Jhong-Min Chen, Caixia Hou, Guojun Wang, Oleg V. Tsodikov and Jürgen Rohr

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Biochemistry
DOI: 10.1021/bi501462g

Plk1 Phosphorylation of IRS2 Prevents Premature Mitotic Exit via AKT Inactivation

April 6th, 2015 by Long Chen, Zhiguo Li, Nihal Ahmad and Xiaoqi Liu

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Biochemistry
DOI: 10.1021/acs.biochem.5b00016

Understanding Thermosensitive Transient Receptor Potential Channels as Versatile Polymodal Cellular Sensors

April 3rd, 2015 by Jacob K. Hilton, Parthasarathi Rath, Cole V. M. Helsell, Oliver Beckstein and Wade D. Van Horn

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Biochemistry
DOI: 10.1021/acs.biochem.5b00071

Active Site and Remote Contributions to Catalysis in Methylthioadenosine Nucleosidases

April 2nd, 2015 by Keisha Thomas, Scott A. Cameron, Steven C. Almo, Emmanuel S. Burgos, Shivali A. Gulab and Vern L. Schramm

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Biochemistry
DOI: 10.1021/bi501487w

Electrostatic Occlusion and Quaternary Structural Ion Pairing Are Key Determinants of Cu(I)-Mediated Allostery in the Copper-Sensing Operon Repressor (CsoR)

April 2nd, 2015 by Feng-Ming James Chang, Julia E. Martin and David P. Giedroc

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Biochemistry
DOI: 10.1021/acs.biochem.5b00154

Correction to Mechanism and Functional Implications of the Heme-Induced Binding Promiscuity of IgE

April 2nd, 2015 by Maya Hadzhieva, Tchavdar L. Vassilev, Lubka T. Roumenina, Jagadeesh Bayry, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes and Jordan D. Dimitrov

Biochemistry
DOI: 10.1021/acs.biochem.5b00323

Molecular Dynamics Studies of Modular Polyketide Synthase Ketoreductase Stereospecificity

April 2nd, 2015 by Mauro L. Mugnai, Yue Shi, Adrian T. Keatinge-Clay and Ron Elber

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Biochemistry
DOI: 10.1021/bi501401g

Apolipoprotein AI Deficiency Inhibits Serum Opacity Factor Activity against Plasma High Density Lipoprotein via a Stabilization Mechanism

April 2nd, 2015 by Corina Rosales, Niket Patel, Baiba K. Gillard, Dedipya Yelamanchili, Yaliu Yang, Harry S. Courtney, Raul D. Santos, Antonio M. Gotto and Henry J. Pownall

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Biochemistry
DOI: 10.1021/bi501486z

Conversion of Aminodeoxychorismate Synthase into Anthranilate Synthase with Janus Mutations: Mechanism of Pyruvate Elimination Catalyzed by Chorismate Enzymes

April 2nd, 2015 by Justin E. Culbertson, Dong hee Chung, Kristin T. Ziebart, Eduardo Espiritu and Michael D. Toney

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Biochemistry
DOI: 10.1021/acs.biochem.5b00013

Enzymatic Oxidation of Methane

April 1st, 2015 by Sarah Sirajuddin and Amy C. Rosenzweig

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Biochemistry
DOI: 10.1021/acs.biochem.5b00198