Impact of Amyloid Precursor Protein Hydrophilic Transmembrane Residues on Amyloid-Beta Generation

April 23rd, 2015 by Felix Oestereich, Heiko J. Bittner, Christoph Weise, Lisa Grohmann, Lisa-Kristin Janke, Peter W. Hildebrand, Gerhard Multhaup and Lisa-Marie Munter

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Biochemistry
DOI: 10.1021/acs.biochem.5b00217

Spectroscopic Studies Reveal That the Heme Regulatory Motifs of Heme Oxygenase-2 Are Dynamically Disordered and Exhibit Redox-Dependent Interaction with Heme

April 22nd, 2015 by Ireena Bagai, Ritimukta Sarangi, Angela S. Fleischhacker, Ajay Sharma, Brian M. Hoffman, Erik R. P. Zuiderweg and Stephen W. Ragsdale

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Biochemistry
DOI: 10.1021/bi501489r

The C-Terminal Heme Regulatory Motifs of Heme Oxygenase-2 Are Redox-Regulated Heme Binding Sites

April 22nd, 2015 by Angela S. Fleischhacker, Ajay Sharma, Michelle Choi, Andrea M. Spencer, Ireena Bagai, Brian M. Hoffman and Stephen W. Ragsdale

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Biochemistry
DOI: 10.1021/acs.biochem.5b00266

Biochemical Characterization of the Roles of Glycines 24 and 27 and Threonine 179 in Tropomyosin from the Fast Skeletal Trunk Muscle of the Atlantic Salmon

April 22nd, 2015 by Korrina R. Fudge and David H. Heeley

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Biochemistry
DOI: 10.1021/acs.biochem.5b00156

Measuring Propargyl-Linked Drug Populations Inside Bacterial Cells, and Their Interaction with a Dihydrofolate Reductase Target, by Raman Microscopy

April 21st, 2015 by Hossein Heidari-Torkabadi, Tao Che, Michael N. Lombardo, Dennis L. Wright, Amy C. Anderson and Paul R. Carey

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Biochemistry
DOI: 10.1021/acs.biochem.5b00202

Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies

April 20th, 2015 by Mitesh Nagar, Brittney N. Wyatt, Martin St. Maurice and Stephen L. Bearne

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Biochemistry
DOI: 10.1021/acs.biochem.5b00221

Challenges in the Interpretation of Protein H/D Exchange Data: A Molecular Dynamics Simulation Perspective

April 20th, 2015 by Robert G. McAllister and Lars Konermann

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Biochemistry
DOI: 10.1021/acs.biochem.5b00215

Examining Reaction Specificity in PvcB, a Source of Diversity in Isonitrile-Containing Natural Products

April 20th, 2015 by Jing Zhu, Geoffrey M. Lippa, Andrew M. Gulick and Peter A. Tipton

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Biochemistry
DOI: 10.1021/acs.biochem.5b00255

Functional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors

April 17th, 2015 by Nelli Mnatsakanyan, Sita Nirupama Nishtala, Akash Pandhare, Mariana C. Fiori, Raman Goyal, Jonathan E. Pauwels, Andrew F. Navetta, Afzal Ahrorov and Michaela Jansen

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Biochemistry
DOI: 10.1021/acs.biochem.5b00203

Spectroscopic Determination of Distinct Heme Ligands in Outer-Membrane Receptors PhuR and HasR of Pseudomonas aeruginosa

April 17th, 2015 by Aaron D. Smith, Anuja R. Modi, Shengfang Sun, John H. Dawson and Angela Wilks

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Biochemistry
DOI: 10.1021/acs.biochem.5b00017