Signal transduction: Lowered exchange rates

March 18th, 2016 by Grant Miura

Nature Chemical Biology 12, 201 (2016). doi:10.1038/nchembio.2054

Author: Grant Miura

Transcription: 7SK’s enhanced roles

March 18th, 2016 by Terry L. Sheppard

Nature Chemical Biology 12, 201 (2016). doi:10.1038/nchembio.2053

Author: Terry L. Sheppard

Drug discovery: One without the other

March 18th, 2016 by Mirella Bucci

Nature Chemical Biology 12, 201 (2016). doi:10.1038/nchembio.2055

Author: Mirella Bucci

Role of Electrostatic Interactions in Binding of Peptides and Intrinsically Disordered Proteins to Their Folded Targets: 2. The Model of Encounter Complex Involving the Double Mutant of the c-Crk N-SH3 Domain and Peptide Sos

March 14th, 2016 by Tairan Yuwen, Yi Xue and Nikolai R. Skrynnikov

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Biochemistry
DOI: 10.1021/acs.biochem.5b01283

Light-controlled modulation of gene expression by chemical optoepigenetic probes

March 14th, 2016 by Surya A Reis

Nature Chemical Biology 12, 317 (2016). doi:10.1038/nchembio.2042

Authors: Surya A Reis, Balaram Ghosh, J Adam Hendricks, D Miklos Szantai-Kis, Lisa Törk, Kenneth N Ross, Justin Lamb, Willis Read-Button, Baixue Zheng, Hongtao Wang, Christopher Salthouse, Stephen J Haggarty & Ralph Mazitschek

  • Posted in Nat Chem Biol, Publications
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Optoepigenetics: An acetylation photoswitch

March 14th, 2016 by Andreas S Madsen

Nature Chemical Biology 12, 306 (2016). doi:10.1038/nchembio.2049

Authors: Andreas S Madsen & Christian A Olsen

Histone 3 lysine 9 acetylation (H3K9ac) levels were modulated by photoresponsive histone deacetylase (HDAC) inhibitors to perturb the transcription of genes involved in cell cycle regulation and mitochondrial function.

Methyl-esterified 3-hydroxybutyrate oligomers protect bacteria from hydroxyl radicals

March 14th, 2016 by Janne J Koskimäki

Nature Chemical Biology 12, 332 (2016). doi:10.1038/nchembio.2043

Authors: Janne J Koskimäki, Marena Kajula, Juho Hokkanen, Emmi-Leena Ihantola, Jong H Kim, Heidi Hautajärvi, Elina Hankala, Marko Suokas, Johanna Pohjanen, Olga Podolich, Natalia Kozyrovska, Ari Turpeinen, Mirva Pääkkönen, Sampo Mattila, Bruce C Campbell & Anna Maria Pirttilä

  • Posted in Nat Chem Biol, Publications
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[NiFe]-Hydrogenase Maturation

March 13th, 2016 by Michael J. Lacasse and Deborah B. Zamble

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Biochemistry
DOI: 10.1021/acs.biochem.5b01328

Efficient Analysis of Systems Biology Markup Language Models of Cellular Populations Using Arrays

March 8th, 2016 by Leandro Watanabe and Chris J. Myers

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ACS Synthetic Biology
DOI: 10.1021/acssynbio.5b00242

Survival of Phenotypic Information during Cellular Growth Transitions

March 7th, 2016 by J. Christian J. Ray

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ACS Synthetic Biology
DOI: 10.1021/acssynbio.5b00229