Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase

December 12th, 2016 by Ruchi Jain Dey

Nature Chemical Biology 13, 210 (2017). doi:10.1038/nchembio.2254

Authors: Ruchi Jain Dey, Bappaditya Dey, Yue Zheng, Laurene S Cheung, Jie Zhou, David Sayre, Pankaj Kumar, Haidan Guo, Gyanu Lamichhane, Herman O Sintim & William R Bishai

  • Posted in Nat Chem Biol, Publications
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Single-molecule analysis reveals multi-state folding of a guanine riboswitch

December 12th, 2016 by Vishnu Chandra

Nature Chemical Biology 13, 194 (2017). doi:10.1038/nchembio.2252

Authors: Vishnu Chandra, Zain Hannan, Huizhong Xu & Maumita Mandal

  • Posted in Nat Chem Biol, Publications
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Rewiring human cellular input–output using modular extracellular sensors

December 12th, 2016 by Kelly A Schwarz

Nature Chemical Biology 13, 202 (2017). doi:10.1038/nchembio.2253

Authors: Kelly A Schwarz, Nichole M Daringer, Taylor B Dolberg & Joshua N Leonard

  • Posted in Nat Chem Biol, Publications
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Precise small-molecule recognition of a toxic CUG RNA repeat expansion

December 12th, 2016 by Suzanne G Rzuczek

Nature Chemical Biology 13, 188 (2017). doi:10.1038/nchembio.2251

Authors: Suzanne G Rzuczek, Lesley A Colgan, Yoshio Nakai, Michael D Cameron, Denis Furling, Ryohei Yasuda & Matthew D Disney

  • Posted in Nat Chem Biol, Publications
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A Comparison between the Photoactivation Kinetics of Human and Bovine Rhodopsins

December 9th, 2016 by Chie Funatogawa, Istvan Szundi and David S. Kliger

TOC Graphic

Biochemistry
DOI: 10.1021/acs.biochem.6b00953

Sequential and Coupled Proton and Electron Transfer Events in the S2 → S3 Transition of Photosynthetic Water Oxidation Revealed by Time-Resolved X-ray Absorption Spectroscopy

December 5th, 2016 by Ivelina Zaharieva, Holger Dau and Michael Haumann

TOC Graphic

Biochemistry
DOI: 10.1021/acs.biochem.6b01078

Mechanisms of Protein Translocation on DNA Are Differentially Responsive to Water Activity

December 5th, 2016 by Brigitte S. Naughton and Norbert O. Reich

TOC Graphic

Biochemistry
DOI: 10.1021/acs.biochem.6b00872

Genome-wide chemical mapping of O-GlcNAcylated proteins in Drosophila melanogaster

December 5th, 2016 by Ta-Wei Liu

Nature Chemical Biology 13, 161 (2017). doi:10.1038/nchembio.2247

Authors: Ta-Wei Liu, Mike Myschyshyn, Donald A Sinclair, Samy Cecioni, Kevin Beja, Barry M Honda, Ryan D Morin & David J Vocadlo

  • Posted in Nat Chem Biol, Publications
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Mutations along a TET2 active site scaffold stall oxidation at 5-hydroxymethylcytosine

December 5th, 2016 by Monica Yun Liu

Nature Chemical Biology 13, 181 (2017). doi:10.1038/nchembio.2250

Authors: Monica Yun Liu, Hedieh Torabifard, Daniel J Crawford, Jamie E DeNizio, Xing-Jun Cao, Benjamin A Garcia, G Andrés Cisneros & Rahul M Kohli

  • Posted in Nat Chem Biol, Publications
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Quantitating drug-target engagement in single cells in vitro and in vivo

December 5th, 2016 by J Matthew Dubach

Nature Chemical Biology 13, 168 (2017). doi:10.1038/nchembio.2248

Authors: J Matthew Dubach, Eunha Kim, Katherine Yang, Michael Cuccarese, Randy J Giedt, Labros G Meimetis, Claudio Vinegoni & Ralph Weissleder

  • Posted in Nat Chem Biol, Publications
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